Adlung Lab on Mythryl: “Crazy mechanism: Spiga et al. show how the toxin BFT reprograms…”

Crazy mechanism: Spiga et al. show how the toxin BFT reprograms colonocytes to fermentation, raising lactate and oxygen so anaerobic Bacteroides fragilis can grow oxidatively in the inflamed gut. Broad Institute @cp-cell.bsky.social doi.org/10.1016/j.ce... 🧪

doi.orgAn anaerobic pathogen rewires host metabolism to fuel oxidative growth in the inflamed gutTo colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How anaerobic p…

21/5/26, 12:08 pm0 reposts3 likes

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