Adlung Lab on Mythryl: “"This work identifies EP2 signaling in tissue-resident macrophages…”

"This work identifies EP2 signaling in tissue-resident macrophages as a central regulator of organ-wide aging through its control of senescent neutrophil clearance, reframing aging as a failure of active cellular clearance rather than passive degeneration." www.science.org/doi/10.1126/... 🧪

science.orgRestored clearance of senescent neutrophils by tissue-resident macrophages limits organ agingAging disrupts tissue homeostasis across organ systems. Here, we identify tissue-resident macrophages (TRMs) as central coordinators of age-related organ decline through impaired clearance of senescen...

20/7/26, 9:13 am0 reposts5 likes

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