Adlung Lab on Mythryl: “Interesting mechanistic study in Nature Metabolism showing that…”

Interesting mechanistic study in Nature Metabolism showing that macrophages in brown adipose tissue release itaconate to suppress succinate uptake and in turn thermogenesis in brown adipocytes: www.nature.com/artic... 🧪

nature.comMacrophage-derived itaconate is a negative regulator of adipose tissue thermogenesisNature Metabolism - Tang et al. reveal that macrophage-derived itaconate acts as a paracrine inhibitor of adipose tissue thermogenesis by blocking succinate uptake into brown adipose tissue.

26/8/26, 1:25 pm0 reposts2 likes

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