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(1) a linked food database of more than 400 food items that includes nutrition and genomic information with multiple fallback strategies (partial assemblies, higher ranks)

(2) a high specificity identification and quantification pipeline that reliably identifies metagenomic reads coming from food items even when those make up less than 0.001% of the total DNA

One new things we added since the preprint is validation with two controlled feeding studies. In both, MEDI was able to detect the dietary intervention . There was also good agreement with some micro- and macronutrients when creating a standardized portion out of the detected food items.