How does DNA remain confined to dying cells despite its fragmentation? @mfdspicer.bsky.social @rcollepardo.bsky.social @gerlichlab.bsky.social et al show histone deacetylation compacts apoptotic chromatin, preventing it from entering apoptotic extracellular vesicles link.springer.com/article/10.1...
link.springer.comElectrostatic control of chromatin compaction safeguards against apoptotic DNA release - The EMBO JournalApoptosis involves extensive intracellular reorganisation to facilitate the clearance of dying cells. A key step in this process is the destruction of the genome through fragmentation by caspase-activ...
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