Emmanuel Amzallag, Eran Hornstein and colleagues show that the E3 #ubiquitin ligase MKRN2 maintains granulostasis by preventing the accumulation of misfolding-prone DRiPs into #StressGranules. -> link.springer.com/article/10.1...
link.springer.comThe E3 ligase MKRN2 prevents DRiP accumulation in stress granules and maintains granulostasis - EMBO ReportsStress granules (SGs) are transient cytoplasmic biomolecular condensates that play a role in the cellular response to proteotoxic stress. It has been previously shown that ubiquitination regulates SG ...
1 repost1 like