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JAMA
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🧵 Presented at #LIVES2026: In mechanically ventilated adults with #AcuteHypoxemicRespiratoryFailure, an inhaled sedation strategy using isoflurane with intravenous adjuncts as needed did not reduce hospital mortality vs intravenous sedation. ja.ma/3VGMLKg

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JAMA
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💬 Editorial: In adults with #AcuteRespiratoryFailure receiving #MechanicalVentilation, inhaled sedation with isoflurane did not improve hospital mortality, intensive care unit–free days, or ventilator-free days compared with usual intravenous sedation. ja.ma/47fouNV

JAMA
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💬 Editor's Note: In mechanically ventilated adults with #AcuteHypoxemicRespiratoryFailure, an inhaled sedation strategy using isoflurane with intravenous adjuncts as needed did not reduce hospital mortality compared with intravenous sedation alone. ja.ma/4yOnZ9z

JAMA
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📊 Research Summary: In #CriticalCare, #InhaledSedation with isoflurane was associated with fewer delirium- and coma-free days and more adjunctive therapies for hypoxemia vs intravenous sedation. ja.ma/4s5cgkw