@maggieutgaard.bsky.social, @myosincity.bsky.social, @pwoakes.bsky.social et al. show that #septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the #nucleus. rupress.org/jcb/article/... #Cytoskeleton #Mechanobiology
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See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
rupress.orgSeptins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stressMayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
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