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Why do association studies prioritize trait-specific variants??? A quick thread about the importance of thinking about all traits at once 👇 1/6 (🧪🧬)

On top of these, every ‘trait’ is arbitrarily defined (to some extent). So is ‘trait-specific’…

For a single locus, I agree! I even have a mug, courtesy of @roshnipatel.bsky.social, that says "TRAITS AREN'T REAL". Across loci I'm less convinced -- regardless of how one defines traits, one can talk about whether a given locus is more or less trait-specific than another.