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Jeff Spence
@jeffspence.github.io

@roshnipatel.bsky.social and I wrote about using biobanks to learn about evolution, and how those findings shape interpretations of association studies. We focused on estimating evolutionary constraint and relating relating selection on variants to selection on traits and include open questions.

arXiv q-bio.PE Populations and Evolution@qbiope-bot.bsky.social

Jeffrey P. Spence, Roshni A. Patel: Insights into human evolution from large genetic biobanks https://arxiv.org/abs/2609.12297 https://arxiv.org/pdf/2609.12297 https://arxiv.org/html/2609.12297

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Jeff Spence
@jeffspence.github.io

Just to prevent disappointment among people really interested in very meta stuff, we focus on *relating selection on variants to selection on traits* not on _relating_ relating selection on variants to selection on traits.