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3️⃣ Childhood vaccine uptake in the UK remains relatively high, but confidence is declining and coverage has slipped enough to contribute to outbreaks of preventable diseases such as measles. Misinformation plays a causal role in this erosion of uptake. 3/10

4️⃣ We review historical and recent cases—from the Wakefield MMR hoax to HPV campaigns in Japan and Ireland—showing how concentrated misinformation can drive sharp drops in coverage and thousands of preventable cancer cases and deaths. 4/10

5️⃣ The evidence base includes systematic reviews and experiments demonstrating that exposure to vaccine misinformation reduces intentions to vaccinate and is linked to real-world uptake patterns, including via social media amplification. 5/10