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1) 🇪🇺 Good news! The European Union has awarded € 7.5 million for a big ME/CFS consortium that will study biological mechanisms in hundreds of patients. This is a major milestone for ME/CFS research in Europe.

2) The project is called DISCOVER-ME. It's led by Eva Untersmayr at the Medical University of Vienna and includes more than 20 partners across Europe. The European ME Alliance (EMEA) is involved as patient representatives. The grant runs for 4 years, until 2030.

3) The project will investigate biomarkers across (epi)genetic, immune, metabolic, neuroendocrine, and vascular domains. It will phenotype 2,000 patients and perform multi-omics profiling on more than 900 samples from five different European biobanks.

4) It's unclear what specific tests and analyses they will do, but the large sample size will certainly help to identify smaller effects and subgroups of patients. The project also mentions "AI-assisted stratification" and "in silico testing of therapeutic hypotheses"

6) This project was funded under the 2025 Horizon Europe call "Tackling high-burden for patients and under-researched medical conditions," but earlier this year there was also one on post-infectious conditions, where hopefully more ME/CFS and Long Covid projects will be funded.