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Online now!✨Martinez, Morandini et al identify a role for cGAS in chromatin organization: cGAS knockout mice show compromised heterochromatin organization, LINE1 depression, inflammation, and shortened lifespan
nature.comcGAS-deficient mice display premature aging associated with derepression of LINE1 elements and inflammation - Nature AgingDemonstrating a role for cyclic GMP–AMP synthase (cGAS) in chromatin organization, Martinez, Morandini and colleagues report that cGAS-knockout mice exhibit compromised heterochromatin organization, L...
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