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@natmethods.nature.com

Paired-Damage-seq is an in situ labeling-by-repair strategy for joint profiling of oxidative and ssDNA damage alongside gene expression, in single cells. www.nature.com/articles/s41...

28/3/25, 5:14 pm5 reposts9 likes

Nature Methods

@natmethods.nature.com

28 Mar 2025

And for a quick summary, read the Research Briefing here: www.nature.com/articles/s41...

nature.comSimultaneous single-cell DNA damage profiling and RNA sequencing by Paired-Damage-seq - Nature MethodsWe developed Paired-Damage-seq to profile oxidative DNA damage and single-stranded DNA damage jointly with gene-expression analysis in single cells. By dissecting cell-type-specific genome vulnerabili...