Nature research paper: Clonal driver neoantigen loss under EGFR TKI and immune selection pressures https://go.nature.com/4k6SCQD
go.nature.comClonal driver neoantigen loss under EGFR TKI and immune selection pressures - NatureWe show the evolution of a case of EGFR mutant lung cancer treated with a combination of erlotinib, osimertinib, radiotherapy and a personalized neopeptide vaccine targeting somatic mutations, including EGFR exon 19 deletion.
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