Nature research paper: Ageing promotes metastasis via activation of the integrated stress response go.nature.com/4uoWp0M
go.nature.comAgeing promotes metastasis via activation of the integrated stress response - NatureAgeing reprograms the evolutionary trajectory of KRAS-driven lung adenocarcinoma, limiting primary tumour growth while promoting metastatic dissemination through epigenetic activation of the integrated stress response, and a therapeutic opportunity in older patients is revealed.
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