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1/ ๐ŸฆŸ Big news: #Pathoplexus now supports Dengue virus & Yellow Fever virus - two arboviruses responsible for over 400 million infections and up to 94,000 deaths per year. Here's whatโ€™s new in our latest update ๐Ÿ‘‡๐Ÿป Read the full update: pathoplexus.org/news/2026-03... ๐Ÿ“ฐ

2/ ๐Ÿ—ฃ๏ธ Dr Anderson Brito (ITpS, Brazil) explained the importance of this: "Integrating Dengue & Yellow Fever into Pathoplexus means providing endemic countries a transparent, equitable way to share data under terms that protect generators' rights - essential for public health."

3/ ๐Ÿ“Š Data growth: Since November, over 1,500 new directly-submitted sequences have been added across six pathogens, from labs in Africa, Europe, Asia, and the Americas. We now host over 10,400 directly-submitted sequences total.

4/ ๐Ÿ“Š Highlights include: - 593 new RSV-A sequences (Australia, Kenya, Netherlands, Argentina & more) - 445 new RSV-B sequences (Australia, Germany, Kenya, Brazil & more) - 357 new measles sequences - see below! - 130 new mpox sequences, including the 1st from Angola & India

5/ ๐Ÿงซ On the first full-genome measles sequences from Senegal, Dr Idrissa Dieng (Institut Pasteur de Dakar) noted: "By sharing through Pathoplexus, we ensure that African-generated data are visible, valued, and integrated into international public health action." ๐ŸŒ

6/ ๐Ÿ’ฐ Funding news: We're grateful to have received a $500,000 grant from Kanro, the philanthropic initiative supported by Vitalik Buterin. This helps sustain and expand our open infrastructure for transparent, equitable pathogen genomic data sharing. ๐Ÿ™

7/ ๐ŸŒ Policy & governance: Pathoplexus has been included as a 'Relevant Stakeholder' in the WHO Pathogen Access and Benefits Sharing IGWG negotiations - allowing us to participate directly and share our experience running an open-access, restricted-use system.

8/ ๐Ÿ› ๏ธ Tech improvements: - Reverse complement retries now boost alignment success - New CCHF dataset with lineages for the S segment - Simpler multi-segment upload with the new fastaIds field - Mutation search redesigned for segmented viruses - no need to append segment name!

9/ ๐Ÿ› ๏ธ More tech: - Improved group management - warnings for duplicate group names & easier ways to find & join existing groups - Expanded measles dataset via higher-level INSDC taxon ingestion (thanks to Jover Lee for the tip!)

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10/ ๐ŸŽค We've been busy on the road! Highlights: - Talks at Imperial College London, LS2 , BRC Consortium, SSI Denmark, DeZi & UNITEDengue and more ๐Ÿ“Œ Next up: 18 March - Emma at the 35th Annual Meeting of the Society for Virology!

11/ ๐Ÿคฒ๐Ÿป As always, thank you to our submitters, curators, partners, and community ๐Ÿ™ Upload your sequences, cite your SeqSets (DOIs matter!), and tell us what you'd like to see next! ๐Ÿ”— Full update: pathoplexus.org/news/2026-03... #OpenData #OpenScience #PublicHealth #Dengue #YellowFever

pathoplexus.orgPathoplexus | Expanding Pathoplexus: Dengue and Yellow Fever Virus addedPathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.