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Publication alert 🚨 & mini thread 🧵: Modulating corticospinal excitability with transcranial ultrasound stimulation: meta-analytic evidence of online and offline effects With @eester.bsky.social, Marietta Papadatou-Pastou, & @nkonstantinou.bsky.social 1/5 www.sciencedirect.com/science/arti...

sciencedirect.comModulating corticospinal excitability with transcranial ultrasound stimulation: meta-analytic evidence of online and offline effectsCheck access to the full text by signing in through your organization.

Phivos Phylactou

@phivph.com

During the past few years, evidence of human neuromodulation through Transcranial Ultrasound Stimulation (TUS) has been growing. We therefore found it timely to systematically accumulate & meta-analyse the current evidence. 2/5

1/7/26, 4:44 pm0 reposts0 likes

Phivos Phylactou

@phivph.com

1 July

This provides the field with a dataset representative of the state-of-the-art & robust estimates of TUS effects. 3/5

Phivos Phylactou

@phivph.com

1 July

Key findings: - Online TUS systematically reduces corticospinal excitability as indexed by a reduction of motor evoked potentials (MEPs). This likely indicates that online TUS increases GABAa mediated inhibition. 4/5

Phivos Phylactou

@phivph.com

1 July

- Bidirectional neuromodulatory effects are possible. Changes in sonication parameters of common protocols (e.g., theta-burst or low-intensity TUS) can result in both inhibition and excitation. 5/5