Science Magazine on Mythryl: “The protein GAME15 is the missing link in the pathway that Solanum…”

The protein GAME15 is the missing link in the pathway that Solanum plants like potatoes use to make molecules for pest defense, a new Science study finds. The results pave the way for innovative applications in agriculture and biotechnology.

scim.agA cellulose synthase–like protein governs the biosynthesis of Solanum alkaloidsDecades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heterologous hosts has remained a challenge. We discovered...

9/1/25, 4:35 pm10 reposts31 likes

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