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Probably. With a car tire at ~30psi and the cable thin enough that the tire can conform around it, the force squishing the cable is likely less than from a person stepping on it. But, very interesting to explore experimentally!

"It depends..." If any of the conductors break, no. As long as continuity is maintained I... don't know. I haven't done much with 5GBASE-T so I don't know how much headroom is built into the spec. Gut guess would be you can. One way to find out!