Daniel Diaz on Mythryl: “Thanks @shunhuahan.bsky.social for sharing with me.”

A parent with #T1D gives the child a sub-5 % early-life risk, but a parent who carries a T1D genetic burden in the top 1% can push the child’s risk higher (even if that parent does not have #T1D!) So in some cases PGS > Family History of T1D (excluding if both parents have T1D) #Diabetes #Genomics

Waggoner Lab@labwaggoner.bsky.social

Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms www.cell.com/cell-genomic... @andganna.bsky.social

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