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For wine/dosbox/scummvm I use Lutris, for emulators its ES-DE, and Heroic for Epic

I use both. I go with Heroic by default, since it's simpler and works well in Flatpak, as well as supporting Windows as well. Lutris can be a hassle when you're manually adding a lot of games. But it has its uses.

In my experience HGL is more reliable when installing EGS games, also I prefer the UI and simplified settings menu. For everything else I use either Steam or Lutris, the community install scripts help with a lot of hard to run games.