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A personalized neoantigen vaccine + Montanide/poly-ICLC/ipilimumab reshapes the T cell landscape in melanoma patients: - Strong CD8+ responses - TCR repertoires expanded beyond anti–PD-1 - Vaccine-specific TILs identified post-treatment www.cell.com/cell/abstrac...? #Neoantigen #Melanoma #Tcells

cell.comA multi-adjuvant personal neoantigen vaccine generates potent immunity in melanomaA personalized neoantigen peptide vaccine formulated with Montanide plus poly-ICLC and administered with local ipilimumab plus systemic nivolumab induces robust neoepitope-specific T cell responses an...

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