Institut Pasteur researchers developed "optonanobody": a light-controlled nanobody targeting α7 nicotinic receptors. Switch receptors on/off with light, no genetic editing needed. New research tool for Alzheimer's, Parkinson's & schizophrenia. #Neuroscience ↘️ pubs.acs.org/doi/10.1021/...
pubs.acs.orgAn Optonanobody for Reversible Photoactivation of Recombinant and Native α7 Nicotinic ReceptorsPhotopharmacology, which enables the precise optical control of endogenous receptor activity, represents a powerful approach in neuroscience. However, photochromic diffusible ligands often exhibit lim...
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