Institut Pasteur | 130 years of biomedical research

Meet the giant Sissivirus (and its #virophage)! With 4 Mbp genome, Sissivirus is the champion of all known viruses (by genome size). Check the preprint to learn how it got so big. The study led by Julien Andreani, Frederik Schulz @fmschu.bsky.social & Bernard La Scola www.biorxiv.org/content/10.6...

Our completely 𝗿𝗲𝗻𝗲𝘄𝗲𝗱 𝗠𝗢𝗢𝗖 takes you from the cellular biology of Plasmodium to treatments, immune response, and control and elimination strategies. 🧬 𝗡𝗼𝘄 𝘄𝗶𝘁𝗵 𝗮 𝗻𝗲𝘄 𝗰𝗵𝗮𝗽𝘁𝗲𝗿 𝗼𝗻 𝗚𝗲𝗻𝗼𝗺𝗶𝗰𝘀. 👉 Register now!!! : www.fun-mooc.fr/en/courses/m... @pasteur.fr

The updated free online course Resistance to Antibacterial Agents, produced by the Institut Pasteur, will start on Nov. 3, 2026. Subtitles in English, French, Spanish. 💊🦠How does antibioresistance emerge and spread? How to tackle the issue in a One Health approach? 👉 Register here : bit.ly/4juUdSE

Very happy to see this work out in Cell Reports! Led by Ana Morao, who was the driving force behind the project from beginning to end. Great collaboration between @pasteur.fr, @ercanlab.bsky.social at NYU, and Legnini lab @ilegnini.bsky.social at Human Technopole. www.cell.com/cell-reports...

👩‍🎓🧬I am looking for a PhD candidate for the ADAPT project Ancestry and Demographic-Aware Prioritization of drug Targets: Gathering genetic evidence to elucidate drug target potential The PhD will be hosted in the Statistical Genetics Unit @ggspasteur.bsky.social at @pasteur.fr in beautiful Paris.

PhD opportunity @ Institut @pasteur.fr, with Gabriel Lepousez, for applications to the competitive PPU PhD Program. Project on voice perception and neuro/immune responses. Seeking strong candidates in neuroscience, programming & signal processing. PPU: www.pasteur.fr/en/about-us/...

📣 PPU-funded PhD opportunity in @sylvainbrisse.bsky.social lab! Join us for the DiRECT project, investigating the genomics, regulation, and therapeutics of diphtheria. Lab experience in bacterial cloning is requested, phage biology is a plus. Apply by 16.11.2026! www.pasteur.fr/en/about-us/...

For colleagues in Paris: mini cryo-EM & IA seminar announcement! On the 23rd of October 11am, in @pasteur.fr , we welcome the great Frosina Stojanovska (Zuse Institute, Berlin) for a talk on **CryoSiam** From Simulations to Cells: Learning Transferable Representations for Cryo-Electron Tomography

📣 7th Fungal Genetics Ile-de-France Symposium - Registration and abstract submission are open 📅 November 18th 📍Institut Jacques Monod 🔗 www.eventbrite.com/e/billets-7t... @cnrs.fr @upcite.bsky.social @pasteur.fr @sfgenetique.bsky.social

Watch a video of #mitochondrialtransfer between #tumorcells on the Mitoblog, featuring Q&A w/ Saenz-de-Santa-Maria & Zurzolo @pasteur.fr on their @natcomms.nature.com @natureportfolio.nature.com #glioblastoma study: mitoworld.org/tunneling-na... #mitoscientists #UMDF #mitocancer #mitochondria

🌟 Plus qu'un jour pour le #Pasteurdon ! 👉 Donnez sur pasteurdon.fr ou envoyez DON par SMS au 92112 pour donner 20€ Merci ! @pasteur.fr

Fier de contribuer, avec tant de personnes et de métiers, aux missions de l’Institut Pasteur. Votre combat pour la vie est aussi le mien. Pour les 20 ans du #Pasteurdon, faites un don sur pasteurdon.fr. @institutpasteur.bsky.social

Info Le Parisien : Kyan Khojandi est le nouveau parrain du Pasteurdon, qui vise 3 millions d'€ de dons cette année. "En tant que comique, je ne sauve pas des vies. Mais si je peux apporter un coup de projecteur à mon humble niveau, tant mieux !" 1/4 www.leparisien.fr/so...

We are recruiting! Excited by ribosomes, translation, cryoEM and maybe malaria parasites? Then we have a fully funded, 3-year PhD position at the Institut Pasteur in Paris waiting for you. All info here: research.pasteur.fr/en/job/phd-p... ⏰ Deadline: November 6, 2026

📢Our article is now published in @natcomms.nature.com ! We show that tumor-specific TRM-like CD8+ T cell induction requires a cooperation between type 1 and type 2 migratory dendritic cells. Find out more: doi.org/10.1038/s414... @nathanvaudiau.bsky.social @pierre-bourdely.bsky.social @pasteur.fr

We have a position open in our core facility in the @pasteur.fr . Please share it and / or apply! forum.image.sc/t/research-e...

🌊 Climate forecasting meets disease prevention! Scientists linked North Atlantic climate patterns to cutaneous leishmaniasis outbreaks in Morocco & Tunisia—now they can predict certain outbreaks up to 12 months in advance. Early warning saves lives. 🔬 📖 www.pasteur.fr/en/whats-new...

L’institut Pasteur a participé à la Marche des fiertés 2026 pour une science plus inclusive, aux côtés de 4 autres instituts de recherche biomédicale : l'Institut Curie, Imagine, le Centre de Recherche des Cordeliers (CRC) et l'Institut de Recherche Saint Louis (IRSL). #prideparis #lgbtqia

[𝗪𝗲𝗯𝗶𝗻𝗮𝗶𝗿𝗲] 𝗟𝗲 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲, 𝘂𝗻 𝗮𝗰𝘁𝗲𝘂𝗿 𝗱𝗲́𝘁𝗲𝗿𝗺𝗶𝗻𝗮𝗻𝘁 𝗱𝗲 𝗹𝗮 𝘀𝗮𝗻𝘁𝗲́ 𝗺𝗲̀𝗿𝗲-𝗲𝗻𝗳𝗮𝗻𝘁 avec Pascale Vonaesch 📅 𝗗𝗮𝘁𝗲 : 15 oct. 2026, 14h (heure de Paris), sur Zoom 📝 𝗜𝗻𝘀𝗰𝗿𝗶𝘃𝗲𝘇-𝘃𝗼𝘂𝘀 𝗶𝗰𝗶 : us02web.zoom.us/webinar/regi... Durée : 1h30 Disponibles en 35 langues grâce à l'IA, pour une meilleure accessibilité

A step forward to control methane production? at long last Kudos to @sgribaldo.bsky.social and @ivo-boneca.bsky.social www.nature.com/articles/s41...

lnkd.in/exDnxM_6 My team at Institut Pasteur Paris, in collaboration with the team of Dr Makhtar Niang at Institut Pasteur de Dakar, are searching for prospective PhD students through the Pasteur-Paris University International Doctoral Program.

Our paper outlining a deep learning-based phenotypic screening method to discover new TB drugs is out in @science.org #ScienceAdvances 💊🦠 It's the result of a great collaboration between the labs of @chzimmer.bsky.social and @awehenkel.bsky.social at @pasteur.fr! 📃 www.science.org/doi/10.1126/...

🍽️ Eating: One Behavior, Many Sciences! Join us Nov 9 at Institut Pasteur for an interdisciplinary exploration of how genes, brains, cultures & environments shape what we eat. Where nutrition meets neuroscience, genetics, anthropology & more. 🧬🧠🌍 📍Paris | 9:30–17:30 🔗 docs.google.com/forms/d/e/1F...

Not every cell react the same way to caspase activation. In our recent study (led by @tomcumming.bsky.social and initiated by @avillars.bsky.social ), we tried to better understand what explains this difference and outlined a role of past caspase exposure 👇 www.nature.com/articles/s41...

Happy to share our latest publication supporting a key role of NK cells in post-treatment control of SIV infection. In this work, we describe how constitutive characteristics of NK cells, present before infection, may influence the outcome after ART interruption. www.nature.com/articles/s41...

Two European cohorts, SysAge and @milieuinterieur.bsky.social, join forces for their first joint symposium: Immune variability across the life course. Oct 29, Institut Pasteur. Keynotes by Yasmine Belkaid and Rose-Anne Kenny. Registration ↘️ research.pasteur.fr/en/event/imm... #Pasteur2030

Interested in #archaea, #methane, #cell-envelopes? New paper out @nature.com ! We discovered an enzyme that specifically cleaves the cell wall of methanogens, revealing a new chemical structure of archaeal peptidoglycan, 50 yrs after its first description www.nature.com/articles/s41... #MicroSky 🧵👇

Dans le cadre de la collaboration entre @pasteur.fr et @upcite.bsky.social au sein de l'atelier de la donnée #FAIRDATACité, trois formations de l'Institut Pasteur sur la gestion des données de recherche en biologie-santé sont ouvertes à la communauté scientifique UPCité. 🖋️➡️ https://swll.to/LBpiea

#Antibiotics A deep-learning model recognises antibiotic modes of action using unlabelled brightfield images of drug-treated bacteria @chzimmer.bsky.social @pasteur.fr @uni-wuerzburg.de @danielkrentzel.bsky.social @kelvinkho.bsky.social @awehenkel.bsky.social #deeplearning #AI4AMR #microbiology

🤖 New AI can "see" antibiotic action on bacteria through microscopy alone—detecting effects invisible to standard tests. A breakthrough that could accelerate antibiotic discovery & combat resistance. 🔬 📖 www.pasteur.fr/en/whats-new...

Fun collaboration with the Van Melderen lab, led by Ludovic Belot on the acquisition and erosion of toxin-antitoxin systems in bacterial chromosomes. academic.oup.com/mbe/article/...

I'd like to introduce a piece of work we did for the paper of @ines-ssm.bsky.social and colleagues in the lab of Chiara Zurzolo in @pasteur.fr www.nature.com/articles/s41...

🏆 The Duquesne Prize 2026 honors Jim Di Santo for his exceptional contributions to immunology—from discovering ILCs to developing innovative cell-based immunotherapies. A visionary leader shaping the future of vaccine & immunotherapy research. 🧬

New paper from the lab, out in Nature Microbiology. We ran CRISPRi screens to ask what genes E. coli needs in order to live in a gut and what this can tell us about the gut environment itself. https://doi.org/10.1038/s41564-026-02471-8

Two-way mitochondrial transfer between GBM tumour cells & astrocytes via nanotubes – a tumour adaptation that could be targeted 📹 Ines Saenz-de-Santa-Maria et al, @pasteur.fr @upcite.bsky.social in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026...

🧬 HIV breakthrough: Institut Pasteur researchers reveal how lenacapavir works—it keeps the HIV capsid intact in the cell nucleus, redirecting the virus away from active genes & crippling replication. A major step toward limiting HIV persistence. 🔬 📖 www.pasteur.fr/en/whats-new...

A game-changer for endometriosis: Scientists at Institut Pasteur discovered that menstrual blood contains biomarkers revealing the disease, enabling diagnosis without surgery. After 7-year waits, this is hope for millions. link.springer.com/article/10.1... @camilleberthelot.bsky.social

Ticks: a growing threat in Europe & worldwide. LabEx IBEID Symposium "Tiny Vectors, Major Threats" | Oct 8, 2026 | Institut Pasteur. Epidemiology, biology & vaccination on the agenda. Register ↘️ research.pasteur.fr/fr/event/tin... #TickBorneDiseases @ibeidlabex.bsky.social

Institut Curie, Paris, symposium: Where Form Takes Shape October 27-28th 2026 (after the yearly International Developmental Biology course) Registration before October 10th (for free !): docs.google.com/forms/d/e/1F... There will be short talks and posters selected from abstracts.

Our collaborative paper, with Daria Bonazzi and @dumenillab.bsky.social is finally out in Nat Comms! Using microfluidic confiners, amazing Laure Leblanc found that confined growth of E. coli uncouples growth and division, as well as pressure and biomass production. tinyurl.com/4zdwrp39

New preprint in the lab! "Single-cell metabolomics reveals infection-specific metabolic reprogramming of human macrophages". Led by Paula Martínez, with @cbuch.bsky.social , Sandrine Aros and @jytinevez.bsky.social How does Legionella pneumophila reshape host metabolism at the single-cell scale? 🧵👇

𝗝𝗼𝗶𝗻 𝘁𝗵𝗲 𝗠𝗢𝗢𝗖 𝗘𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰𝘀, 𝗲𝗻𝗿𝗼𝗹𝗹𝗺𝗲𝗻𝘁 𝗶𝘀 𝗻𝗼𝘄 𝗼𝗽𝗲𝗻! 👉 Register here: www.fun-mooc.fr/en/courses/e... 💬 Course in English with subtitles (English/French) 📆 Course access starts: September 29, 2026 🎓 100% free and self-paced. Paid Certificate Option

📢master or PhD student interested in cell biology ? There are spots left for the Molecular Biology of the Cell course @pasteur.fr. Check the amazing list of lecturers + 1 week practical pocking choano cytokeleton with @thibautbrunet.bsky.social team. Registration 👇 www.pasteur.fr/fr/nous-conn...

See below for an exciting post-doc opportunity at Institut Pasteur with my excellent colleague Aimee Taylor on Synthetic Data Simulation for Malaria Genomic Epidemiology. research.pasteur.fr/en/job/postd...

🚨 New preprint alert! 🚨 Choanoflagellates reorganize their global cytoskeletal architecture within seconds to explore confined microspaces. This is the main PhD work of the amazing @maitefreired.bsky.social www.biorxiv.org/content/10.6... A tread 🧵⬇️

The deadline is coming for our international microbiome-focused symposium !!! Registration is FREE, and we are welcoming abstract submissions for posters and short presentations. Deadline : Sept 30th. research.pasteur.fr/en/event/int...

Muscle with Hustle: Live imaging reveals muscle stem cell activity is impaired in Duchenne muscular dystrophy 📹 @sardeliza.bsky.social et al @pasteur.fr in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026... with John Ankers

Check out our paper on ESCRTs in large DNA viruses. Most enveloped viruses use the host #ESCRT for envelopment, but only mirusviruses and nucleocytoviricots encode it! Congrats @sonaida.bsky.social, @tomdelmont.bsky.social, Ulysse Guyet & Eugene Koonin. @pasteur.fr www.nature.com/articles/s41...

🦠 𝗧𝘄𝗼 𝗼𝘂𝘁𝗯𝗿𝗲𝗮𝗸𝘀, 𝘁𝘄𝗼 𝗱𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝘁 𝘀𝘁𝗼𝗿𝗶𝗲𝘀 Last spring, two viral emergencies struck simultaneously: Andes Hantavirus and Ebola Bundibugyo. Same timeline, yet radically different outcomes. 🎥 To learn more about these viruses, check out our webinar replays : www.youtube.com/playlist?lis...