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The story of scale up of streptomycin for treating TB is an epic one, involving George Merck and his pharmaceutical company--just making enough to do the clinical trial was a challenge newsnetwork.mayoclinic.org/discussion/d...
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Thank you, so interesting! I was reading earlier about how it was discovered by Waksman and then-PhD student Albert Schatz. It seems Schatz was drafted into WWII while working on the project. He returned to the lab a few months later after an injury, and then discovered streptomycin.
journals.asm.orgSelman A. Waksman, Winner of the 1952 Nobel Prize for Physiology or Medicine | Applied and Environmental MicrobiologyABSTRACT The history of the discovery and development of streptomycin is reviewed here from
the personal standpoint of a member of Dr. Selman Waksman's antibiotic screening research
team. The team app...
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