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Paul Knoepfler
@stemcells.bsky.social

Excited about my lab's new paper: Evidence for coordinate CTCF and histone H3.3 activities in K27M diffuse midline gliomas link.springer.com/article/10.1... Aiming for targetable epigenomic dependencies of this fatal childhood brain tumors #DIPG

link.springer.comEvidence for coordinate CTCF and histone H3.3 activities in K27M diffuse midline gliomas - Acta Neuropathologica CommunicationsUp to 80% of diffuse midline gliomas (DMGs) are characterized by a lysine to methionine driver mutation (K27M) in the tail of histone variant H3.3, pointing to likely roles for epigenetic mechanisms i...

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williambramscher.bsky.social
@williambramscher.bsky.social

[S] [A] [T] [O] [R] \-----------------/ [A] |[R] [E] [P] [O] | \-------/ | [T] |[E] |[N]| [E] |[T] <-- The "N" is the Right-Angle Pivot Point! | /-------\ | [O] |[P] [E] [R] [O] /-----------------\ [R] [O] [T] [A] [S] #Gonzo #IndependentWriting #MusicWriting #GMaj7