Andre Faure

AI drug discovery has a data problem. We're fixing it. At ALLOX, we've spent the last few years building something that didn't exist before: a platform that systematically maps functional hotspots at scale, measuring the effects of mutations on protein-protein interactions across the proteome.

Wow. Catalonia has more active clinical trials than the entirety of the UK or Germany. That's wild. From the latest @biocat.cat annual report.

The allosteric landscape of the Src kinase by Toni Beltran, @ajfaure.bsky.social , @crg.eu @sangerinstitute.bsky.social @alloxbio.bsky.social www.science.org/doi/10.1126/...

As the imperial boot of the US and Israel relentlessly pounds the face of the Palestinian people, the EU looks on in silence. Its inaction displays more than just stupidity and hypocrisy, the EU is complicit in genocide. www.theguardian.com/commentisfre...

New preprint from the allostery team www.biorxiv.org/content/10.1...

🎲 Our paper on the genetics, energetics, and allostery in proteins with randomized cores and surfaces is out today @science.org! 🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.

“Nothing is less real than realism. Details are confusing. It is only by selection, by elimination, by emphasis, that we get at the real meaning of things.” — Georgia O'Keeffe

On this day in 1954, the United States orchestrated a coup against Jacobo Árbenz, the progressive and democratically-elected leader of Guatemala, because he sought to restore land to small farmers and Indigenous communities that had been dispossessed by US fruit companies.

Alzheimer’s disease 🧠starts with a molecular domino effect - but what triggers the first piece to fall? In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇 www.science.org/doi/10.1126/...

“Scientists often study the past as obsessively as historians because few other professions depend so acutely on it. Every experiment is a conversation with a prior experiment, every new theory a refutation of the old.” — Siddhartha Mukherjee, The Emperor of All Maladies

Any traders with inside information that Trump was going to walk back his tariffs — some of them, presumably, Trump family members and cronies — just made a fortune. It all feels like chaos until you look more closely at who is winning.

💜Feliz #11F y #DíadelaMujeryNiñaEnLaCiencia💜