Amesh Adalja

Amesh Adalja

@ameshaa.bsky.social

Infectious Disease • Critical Care • EM Physician Independent voice on outbreaks, biosecurity & biothreat preparedness Pittsburgh • NYC Ameshadalja.com

1K followers128 following12.8K posts

“We are creating an environment that is favoring pathogenic fungi and drug resistance,,That means they are likely becoming better at infecting us, and also at evading our treatments. That’s a bad combination.” apple.news/A5cSyfHLDTcS...

apple.newsWhy Dangerous Fungi Are on the Rise — TIMEIn the winter of 2015, Dr. Tom Chiller received a call from public-health officials in Britain. They were panicking. A new fungus was causing devastating infections at a large London hospital. “They w...

“Investigators evaluated an all-in-one assay designed to measure IgG and IgG4 responses simultaneously to Brugia malayi adult antigen and seven recombinant antigens specific to Loa loa, Wuchereria bancrofti, Onchocerca volvulus and Strongyloides stercoralis” idsareporter.com/issues/2026/...

idsareporter.comMultiplex assay improves species-specific parasite diagnosis"These data provide a new framework for clinically useful parasite-specific serology that helps to direct targeted therapeutic options."

“Lancaster County logged 23 new measles cases in the past week, bringing the county total to 478 cases this year. Statewide, the number of people infected with the virus rose by 74 since last Monday, raising Pennsylvania’s total to 1,360 people infected with measles in 2026”

lancasteronline.com478 Lancaster County residents have now been infected with measles this yearLancaster County logged 23 new measles cases in the past week, bringing the county total to 478 cases this year. Statewide, the number of people infected with the virus rose

“In the phase 2 RePreve trial, Lumen Bioscience’s investigational oral biologic LMN-201 plus standard antibiotics achieved global cure in 83.3% of patients with C difficile infection vs 36.4% with placebo, and cut recurrence sixfold (9.1% vs 55.6%) with no drug-related serious adverse events”

contagionlive.comLMN-201 Reduces C difficile Recurrence | Contagion LiveIn the phase 2 RePreve trial, Lumen Bioscience’s investigational oral biologic LMN-201 plus standard antibiotics achieved global cure in 83.3% of patients with C difficile infection vs 36.4% with plac...

“shortened time to complete and sustained resolution of RSV symptoms by up to 1 week in high-risk adults. The antiviral did not, however, improve time to resolution of symptoms to mild or absent, the trial's primary end point” www.contagionlive.com/view/zelicap...

contagionlive.comZelicapavir Shortens RSV Symptoms Despite Missing Primary End Point | Contagion LiveOral zelicapavir cut time to complete RSV symptom resolution by up to 1 week in high-risk adults, but it did not meet its primary end point in a phase 2 trial.

“FBI agents interviewed Unglesbee at his home on Sunday and he told them all the letters contained salt, court records show. He claimed he’d sent the letters after hearing someone talk about similar mailings in the news earlier this month.” www.butlereagle.com/20261026/ill...

butlereagle.comIllinois man charged with mailing white powder to members of CongressSPRINGFIELD, Ill. — A 37-year-old Illinois man is charged with sending threatening letters to members of Congress containing a white powder, including one with a note reading “HAH enjoy the gift,” acc...

“One of the theories the scientists will investigate is a potential link between the patient in Nigeria and the 1st case in Kenya, reported earlier this month in a man who had travelled from Congo..genomic sequencing showed that the viruses that infected the two patients were closely related”

reuters.comEbola scientists to probe Nigeria case origin, Africa CDC saysA team of ​leading Ebola scientists will travel to Nigeria to help investigate how the country’s first patient in more than ‌a decade got infected, Africa CDC Director-General Jean Kaseya said.

“Rush has specialized infrastructure designed to contain highly infectious dangerous pathogens” - which sit unused in lieu of the Kenya quarantine facility located in a country with its own Ebola outbreak abc7chicago.com/post/ebola-o...

abc7chicago.comChicago hospitals say they are prepared as Ebola outbreak grows overseasChicago hospitals say they are more prepared than ever to respond to a potential Ebola case as a deadly outbreak in Africa continues to expand.

“There are some advantages for Kennedy not to have a functioning ACIP..’Kennedy, in appointing his ACIP, wanted to change the schedule, and they haven’t been anywhere near as quick as he’d like them to be’..Delaying the reconstitution of the committee may allow him to make his own recommendations”

theguardian.com‘It’s a mess right now’: RFK’s sweeping changes place new vaccines in limboHealth secretary’s effort to alter makeup of ACIP panel means no new recommendations coming – even as new vaccines are approved

“Our study did not observe any concerning trends in Staphylococcus or Enterococcus resistance rates or MIC distributions over an 8-year period that included a 3-year follow-up after liberalization of daptomycin and linezolid use,” idsareporter.com/issues/2026/...

idsareporter.comRelaxed daptomycin, linezolid restrictions not linked to relevant resistance increases“Our study did not observe any concerning trends ... over an 8-year period that included a 3-year follow-up.”