The Australian Ubiquitin Summit

20 Dec 2025

‼️For our final invited speaker interview, we talked with the amazing Titia Sixma about her work on the role of ubiquitin in DNA regulation, and some #AusUb2025 highlights. Thank you to everyone who came, it was an amazing conference and a great chance to see the breadth of global ubiquitin research!

17 Dec 2025

‼️Towards the end of #AusUb25, we caught up with Jonathan Pruneda to discuss ubiquitin signalling and its relationship with host-pathogen interactions. It was an amazing conference and such a great chance to meet people from across the ubiquitin field 🤩

13 Dec 2025

‼️ Following on from our “M1 chains everywhere!” session at #AusUb25 we took the chance to interview one of the pioneering researchers in this field, Kazuhiro Iwai. Have a look below! ✨✨✨

11 Dec 2025

‼️It was wonderful to have Professor Kay Hoffmann at the #AusUb25 - and even better to get the chance to interview him! Hear about his experiences in industry and academia as well as his love for proteins😁

9 Dec 2025

‼️Have a listen to a little about Kylie Walter’s exciting new research, conference talk, and her experience at #AusUb2025. What did she enjoy most about the conference? More interviews to come in the next week so stay tuned 😁

26 Nov 2025

Today we have Brenda Schulman, Director of the Department of Molecular Machines and Signalling at Max Planck Institute of Biochemistry, as our interviewee at #AusUb2025. Jump in to find out her research focus and conference tips!

@rashmiagrata.bsky.social

25 Nov 2025

It’s hard to believe that #AusUb2025 has already come to an end 😢. Don’t worry though - we’ll still be posting our speaker interviews in the next couple of days. Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇

The Australian Ubiquitin Summit reposted

Rashmi Agrata

25 Nov 2025

What a fantastic few days at The *inaugural* Australian Ubiquitin Summit 🤩 #UbiquitinByTheBay It was fun to contribute behind the scenes in the lead-up, help chair the opening session, host lightning talks, and dive into conversations during the poster session and EMCR panel discussions.

That was our last presentation session at #AusUb2025!!! 🥳We explored the role of #ubiquitin in different diseases, from cancer to chicken pox. A huge thank you to our final speakers: Sandra Nicholson, Yi-Ching Wang, Anindita Puri and Ruey-Hwa Chen.

We hope that you’ve had a wonderful time at #AusUb2025 at Lorne! Please repost to tell us about your biggest win at #AusUb2025! Did you make connections🤝? Learned something exciting💡? Or spotted rare Aussie flora and fauna🐨🦘?

🫣 Can you believe that we are at the last day of #AusUb2025?!?! The second ‘Mechanisms in #Ubiquitination’ session had a focus on deubiquitinases #DUB.

Thank you to our speakers who presented such interesting talks: Titia Sixma, Suhail Nurbhai and Sarah Fritchley (Mission Therapeutics), Malte Gersch, Irina Bezsonova, and Kay Hofmann.

Before we bid goodbye to the beautiful town of Lorne on the Great Ocean Road, make sure to connect with the #AusUb2025 community by following and sharing our page to your connections!

The #EMCR discussion panel wrapped up Day 3 at #AusUb2025 nicely! If you are a PI, what would be your best advice to the EMCR you? Let us know in the comment!

The last session during the #TPD day at #AusUb2025 explored the Translational Journey of TPD. Gwenn Hansen and Kanae Gamo both gave great talks on the topic. While the presentations of the day are all finished, the long anticipated EMCR panel discussion is coming next! #ubiquitin

And that’s our third session of the #TPD day at #AusUb2025 done! Great talks on the forefront of #TPD in Disease Management.

Thank you to all speakers: Hsueh-Chi Sherry Yen, Selina Zhang, Benedikt Kessler, Mengying Zhou, and Fumiaki Ohtake. #ubiquitin #targetedproteindegradation

The Australian Ubiquitin Summit reposted

Min Zhuang from ShanghaiTech University talking about the MARCHF5 mitochondria and peroxisome localised E3 #AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social

The Australian Ubiquitin Summit reposted

Very nice presentation by Phil Chamberlain from Neomorph to kick off the TPD day today at @ausub.bsky.social #AusUb2025 #LorneUbiquitin2025 From the fundamentals of glues to identifying more in the proteome to glue

The Australian Ubiquitin Summit reposted

Learning more about cryptic interaction areas of CRBN during glue binding presented by Lei Liu from Tsinghua University @tsinghuauniversity.bsky.social Work partially in a pre-print @biorxivpreprint.bsky.social #AusUb2025 #LorneUbqiuitin2025 @ausub.bsky.social

Continuing on with our TPD-themed day at #AusUb2025, we just had amazing talks on ‘the Frontiers of Innovation in TPD’ from Eric Fischer, Fleur Ferguson, Johannes Yeh, Man Pan, and Mikihiko Naito. #ubiquitin #TPD #targetedproteindegradation

We’ll soon be releasing exclusive interviews with #AusUb2025 speakers! Spread the word so that no one misses out on top tips from our star speakers.

Day 3 is TPD day at #AusUb2025. We’ve gone off to a flying start with tantalising talks on molecular glues and PROTACs given by Philip Chamberlain, Lei Liu, Nishma Gupta and Stefan Knapp.

Watch this space for updates on our upcoming EMCR lunch and panel discussion which is bound to be exciting - even some of the Aussie wildlife seem keen to join 😆

Time to find out what’s the newest insight on the #ubiquitin-proteosome degradation system from our speakers: Shang-Te (Danny) Hsu, Yasushi Saeki, Indrajit Sahu, and Kylie Walters. While this is our last talk session of Day 2 at #AusUb2025, science goes on at the poster session…

And that's our #AusUb2025 Lightning Teaser Talks over in a flash! #ubiquitin

Congratulations to all speakers: Kouta Nakadai, Xiaoying (Charlotte) Yu, Alina Thielen, Hikaru Tsuchiya, Mai Morita, Mihaela Ficu, Jie Liu, @Sonia Shah, Gwendoline Marbach, and Che Stafford.

Make sure to check out their posters later today during the poster session!

Another session that’s full of star speakers! Thank you Eric Bennet, Pei Yee Tey, Achim Werner, Xiaofeng Zheng and Min Zhuang for your wonderful presentations!

Get excited for the next session at #AusUb2025 which features Lightening Teaser Talks from selected poster presenters!

Day 2 of #AusUb2025 began with the first session on ‘Mechanisms in Ubiquitination’. Thank you to all speakers: Christopher Lima, Chris Tonkin, Kuen-Phon Wu, Bekky Feltham and Sonja Lorenz.

Today’s schedule at #AusUb2025 is fully packed with presentations, lightening talks and poster session. ❓What’s your favourite activity at a conference? Share your thoughts with us!

The Australian Ubiquitin Summit reposted

Eric Bennett coming from @ucsandiego.bsky.social talks about how E3s have plasticity in quality control to facilitate degradation #AusUb2025 #LorneUbiquitin @ausub.bsky.social

The Australian Ubiquitin Summit reposted

@rashmiagrata.bsky.social

@impeiyee.bsky.social from the labs of Sylvie Urbe and Michael Clague presents to us a tale of CTLA4 turnover Some cool stuff published in @liverpooluni.bsky.social @jcb.org #AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social

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Rashmi Agrata

@rashmiagrata.bsky.social

Is there any biomolecule thats not #Ubiquitinated ? 🫣 It was super fun to chair my fav session on 'Ubiquitinating EVERYthing' during the kickstart event of #AusUb2025

The Australian Ubiquitin Summit@ausub.bsky.social

#AusUb25 kicked off with an amazing session on ‘Ubiquitinating Things’. Thank you to all speakers: Brenda Schulman, Jonathan Pruneda, Satpal Virdee, Andrii Gorelik, and Yukiko Yoshida!

The Australian Ubiquitin Summit reposted

Rashmi Agrata

Is there any chain more enigmatic than K27-Ub? 😍 #UbiquitinByTheBay #AusUb2025

The Australian Ubiquitin Summit@ausub.bsky.social

❓What’s your favourite ubiquitin chain type? Let us know in the comments!

The Australian Ubiquitin Summit reposted

Always a pleasure to hear about the world of the HECT E3s from @sonjalorenzlab.bsky.social from Max Planck Institute for Multidisciplinary Sciences Welcome to Australia! Featuring work published in @cp-molcell.bsky.social @natcomms.nature.com #LorneUbiquitin2025 #AusUb2025 @ausub.bsky.social

The Australian Ubiquitin Summit reposted

The unique E2/E3 UBE2O structure presented by Kuen-Phon Wu from Academia Sinica Taiwan #LorneUbiquitin2025 #AusUb2025 @ausub.bsky.social

The Australian Ubiquitin Summit reposted

Day 2 of the conference in Australia Revisiting the E1-E2-E3 cascade with Chris Lima from the Memorial Sloan Kettering Cancer Center @ausub.bsky.social #AusUb2025 #LorneUbiquitin2025

How cool was it to hear the ‘From glycogen to ubiquitin and back again’ story from Professor Sir Philip Cohen (FRS FRSE FAA FFMedSci), a pioneer in ubiquitin research. It was such a pleasure to have him deliver the keynote presentation on Day 1 of #AusUb2025.

lorneubiquitin.orgProgram — The Australian Ubiquitin Summit 2025

This wrapped up presentations of the day nicely as researchers continue to discuss their science over an Aussie welcome BBQ! Eager to know what’s coming tomorrow at #AusUb2025? Check out the program now: www.lorneubiquitin.org/program-2025

After a short break, #AusUb2025 is back to hear about what’s so special about M1 or linear ubiquitin chains from Kazuhiro Iwai, Stephen Tait, Simon Cobbold, and Michael Glickman.

❓What’s your favourite ubiquitin chain type? Let us know in the comments!

#AusUb25 kicked off with an amazing session on ‘Ubiquitinating Things’. Thank you to all speakers: Brenda Schulman, Jonathan Pruneda, Satpal Virdee, Andrii Gorelik, and Yukiko Yoshida!

Let us know your key takeaway from this session using #AusUb2025!

The Australian Ubiquitin Summit reposted

Sir Philip Cohen presenting on the intersection between glycogen metabolism and ubiquitination From insulin signaling to glycogen Really appreciate the historical tour of ubiquitin in innate immunity @ausub.bsky.social #ubiquitin #AusUb2025 #LorneUbiquitin2025

Today is the day! The Inaugural Australian Ubiquitin Summit #AusUb2025 was officially opened by committee chair David Komander.

We were also honoured to have Ebony Hickey welcoming everyone to Gadubanud country with a powerful story. Indigenous Australians have a long and continuing history, and were the first scientists on this land.

Have you already spotted some ‘local residents’ at Lorne? Share photos and tag #AusUb2025!

The Australian Ubiquitin Summit reposted