baucumlab.bsky.social

Excited to share that we just got a notice of award for our first lab R01. Excited to start work on this project. In the words of my 10-year old son - YESSIR.

New article from the lab on what animal models of prenatal opioid exposure have taught us about the consequences of opioid use during pregnancy.

Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

Excited to share publication news for the lab. Our latest work describing a novel conditional neurabin knockout mouse line is available ASAP in ACS Chemical Neuroscience. Open Access version can be found here: pubs.acs.org/doi/10.1021/....

for those in my boat, the designation has changed on my grant from yesterday to this new pergatory

Grant reviewed on Wednesday updated from Not Discussed to "Competitive-not discussed". I think in top half, but not top ~30%. A0 submission, so that is something. Hope that comments are addressable when I get summary statement. Looks like others like @nanopharmnc.bsky.social are in a similar boat

Had 2 grants reviewed this week. One ND and one 28th percentile. At least one was discussed and it was at NIGMS With the new system and given that NIGMS didn’t exclusively use percentiles previously anyway, will see if it has any chance. One more grant getting reviewed this week.

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Just saw my grant in commons that was supposed to be reviewed a month ago was rescheduled to December. Hopefully it is in the top 30% or whatever that gets Discussed. It is listed as a 2 day study section but I thought some study sections are going down to 1 day which is why they change triage line?

After 10 years, I am stepping down as chair of our department and we have an active search going on! Utah is a phenomenal place to live and work and it's been the honor of a lifetime chairing the department founded by Lou Goodman. #MedSky #Neuroskyence Repost! jobs.chronicle.com/job/37914733...

The newest preprint from the Baucum lab is out. Check it out :).

Striatal spinophilin enhances D2R interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression. https://www.biorxiv.org/content/10.1101/2025.09.09.675136v1

I got another ND on my NIH grant. While it’s hard to be too frustrated with the current state of things, this one was super frustrating as scored last time and thought the idea was much stronger and addressed the critiques well from the last round.

👇🏻👇🏻

3 of 4 R01s in limbo as pulled from study section and the one that was actually reviewed was not discussed. Sigh.

This happened to 3 of my 5 grants: assigned, de-assigned, study section canceled, study section rescheduled, grants de-assigned. One should get reviewed and I bet other will be de-assigned again. No chaos here.

Pastrami turned out pretty good. Still wondering, keep doing science or open a bbq joint. Call it “Broken Beaker BBQ”

DOGE is cutting funding for a badly-needed new VA medical center in Indianapolis. Denying healthcare to our veterans isn’t efficiency. It’s cruel. I’ve demanded that DOGE immediately reverse this dangerous decision.

Well the study section that was supposed to meet yesterday and today for one of my grants got an updated date of 04/22 on commons. I still don’t see it or any new ones in the federal register but not sure how long those take to post.

The 2nd of 5 study sections that I have grants being reviewed at got dreaded * - “Denotes this meeting did not take place as scheduled” by it. Federal register is supposedly opened up, but still the last study section posted was on 1/21, so will be 15-35 days at least for rescheduling, I bet.

OK #HoosierSky so this is happening Share amongst your peeps Those who are in science Those who like science Those who have been helped by science Those who value truth and facts Come hang with the cool kids and say hi to some rad scientists

Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

My funding has allowed us to make tools to understand how one specific protein impacts behavioral changes associated with repetitive movements observed in neurodevelopmental disorders.

Super excited to share our newest preprint using proximity labeling and #proteomics and striatal biochemistry to identify new spinophilin interacting proteins and describe a potential role for spinophilin in the regulation of PSD protein expression. www.biorxiv.org/content/10.1...

I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...

Start the new year off right! Make sure you attend this month's Big Ten Neuroscience Seminar Series highlighting research at the Stark Neurosciences Research Institute at Indiana University School of Medicine by @baucumlab.bsky.social and Izabela Facco Caliman on January 27th! Don't miss it it!

Only 5 days left to apply for the 2025 Medical Neuroscience Undergraduate Summer Research program! Come join us for an incredible neuroscience research experience in the fun city of Indianapolis! medicine.iu.edu/research-cen....

🧠✨ Calling all curious high school minds! ✨🧠 Join the Brain Bee competition! 🏆 🗓 When: January 25th, 2025 📍 Where: IU Indianapolis and the IU Health Neuroscience Center 📝 Visit the link for details and registration 👉 science.indianapolis.iu.edu/neuroscience... #BrainBee #Neuroscience #STEM