Bionic Vision Lab

Bionic Vision Lab

@bionicvisionlab.org

👁️🧠🖥️🧪🤖 What would the world look like with a bionic eye? Interdisciplinary research group at UC Santa Barbara. PI: @mbeyeler.bsky.social‬ #BionicVision #Blindness #NeuroTech #VisionScience #CompNeuro #NeuroAI

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New in Neuron 👁️🧠🧪: Can AI help a cortical visual prosthesis control what the brain actually does after electrical stimulation? We used a bidirectional implant to model and shape stimulation-evoked activity in human visual cortex. doi.org/10.1016/j.ne... #UCSB #AI #BionicVision #Neurotechnology

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🎉 Our paper won a Best Paper Award at #ISMAR2026! Huge congrats to co-first authors Apurv Varshney and Lily Turkstra, and the whole team. Only 8 of 754 submissions received the award: top 1.1%. Here’s what we found 🧵

Exciting news from the lab: Emily Joyce has been named an inaugural UC Noyce Graduate Student Fellow, 1 of just 5 selected across the UC system. Her project asks a deceptively hard question: retinal implants can produce color, but can we predict and control it? ucnoyce.org/news/uc-noyc...

ucnoyce.orgUC Noyce Initiative Names Inaugural Class of Graduate Student FellowsFive exceptional graduate students from across the University of California have been named the inaugural UC Noyce Graduate Student Fellows, launching a new program designed to support the next…

New in Neuron 👁️🧠🧪: Can AI help a cortical visual prosthesis control what the brain actually does after electrical stimulation? We used a bidirectional implant to model and shape stimulation-evoked activity in human visual cortex. doi.org/10.1016/j.ne... #UCSB #AI #BionicVision #Neurotechnology

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Finally, the neural response mattered for perception. Recorded population activity predicted whether a phosphene was seen, and its brightness and color, substantially better than stimulation parameters alone. The emerging picture: stimulation → neural response → perception #BCI #Neuroscience

New in Neuron 👁️🧠🧪: Can AI help a cortical visual prosthesis control what the brain actually does after electrical stimulation? We used a bidirectional implant to model and shape stimulation-evoked activity in human visual cortex. doi.org/10.1016/j.ne... #UCSB #AI #BionicVision #Neurotechnology

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Prediction is useful. Control is the harder problem. Given a desired neural response, we used either gradient optimization or an inverse neural network to find a stimulation pattern predicted to produce it, then tested those patterns in vivo. Both beat conventional approaches.

But not every neural response is equally achievable... Evoked activity occupied a low-dimensional neural manifold. Targets farther from that manifold were much harder to reproduce (r = 0.85). The optimized methods also achieved their targets using lower stimulation currents.

New in Neuron 👁️🧠🧪: Can AI help a cortical visual prosthesis control what the brain actually does after electrical stimulation? We used a bidirectional implant to model and shape stimulation-evoked activity in human visual cortex. doi.org/10.1016/j.ne... #UCSB #AI #BionicVision #Neurotechnology

First problem: the same electrical stimulation does not always produce the same neural response. Responses were much more variable across days than within a day, motivating a model that accounts for the brain’s ongoing state rather than treating stimulation as a fixed input-output mapping.

So we trained a deep forward model to predict the population response to multielectrode stimulation. On held-out days, it outperformed 1-to-1, linear, nonlinear, and dictionary-based models across multiple measures of prediction accuracy.

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@science.xyz has announced the European commercial launch of PRIMA, following CE marking under the EU Medical Device Regulation. 👁️🧠🧪 This marks a significant milestone for the bionic vision field after years of clinical development. science.xyz/news/ce-mark/ #BionicVision #NeuroTech #BCI

science.xyzScience Corp. Announces European Commercial Launch of PRIMA, the Only Treatment to Restore Functional Central Vision to Patients with Geographic Atrophy Caused by Age-Related Macular Degeneration, a L...Science Corporation is a clinical-stage medical technology company.

What might #BionicVision actually look like? 👁️🧪 At the #SantaBarbara County Science Fair, high school students found out firsthand with our BionicVisionXR open-source VR simulator, built to study what how bionic eyes might restore real-world function. science.ucsb.edu/news/county-... #UCSB #STEM

science.ucsb.eduAt county science fair, UC Santa Barbara mentors help young researchers see what’s possible | Division of Mathematical, Life and Physical SciencesLocal middle and high school students explored microscopy, virtual reality and bionic vision research through hands-on lab experiences with campus scientists.

Two #BionicVision studies 👁️🧠 from our lab at #ARVO2026: 1. Argus II timing breaks sighted flicker-fusion assumptions: May 5, 8:30–10:15 AM 2. What shapes blind adults’ attitudes toward vision-restoration technology: May 6, 10:15 AM–12:00 PM Come find us in Denver!

Bionic Vision Lab reposted

April 30 marks 100 years of Giles S. Brindley FRS. Pioneer of cortical implants & #BionicVision. 🧠⚡ Architect of modern erectile dysfunction therapy. Gave the most notorious live demo in scientific history. A century of impact. www.bionic-vision.org/people/giles... #Neuroscience #NeuroTech

bionic-vision.orgbionic-vision.org | People | Giles S. Brindley, MDFRSGiles Skey Brindley FRS (b. 1926) is a British physiologist whose audacious experiments and engineering brilliance helped launch modern visual prosthetics, neuro-urology, and the science of color…

Excited to share that two papers from the lab were accepted to #IEEE #EMBC2026 (@embs.org)! 🎉 1. Better symbol design for reading with (future) prosthetic vision 2. Cloud-adaptive preprocessing for visual neuroprostheses under real-world network constraints #BionicVision #NeuroTech

Bionic Vision Lab reposted

En route to #Cosyne2026! 🧠🧪🇵🇹 @bionicvisionlab.org is represented with 2 projects: - control of electrically evoked activity in human V1 - predictive model of mouse V1 recovers cell- and state-dependent tuning Check out our posters on Thursday! #CompNeuroSky #NeuroSkyence

🚨Fuzzing the brain - automated stress testing for ML-driven neurostimulation🚨 As #MachineLearning begins to control electrical stimulation in neural interfaces, how do we know these models are safe? Paper in Journal of Neural Engineering: bionicvisionlab.org/publications... #BCI #neuroskyence

bionicvisionlab.orgFuzzing the brain: Automated stress testing for the safety of ML-driven neurostimulation | Bionic Vision LabWe propose a systematic, quantitative approach to detect and characterize unsafe stimulation patterns in ML-driven neurostimulation systems.
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Our approach borrows an idea from software verification: coverage-guided fuzzing. We systematically mutate inputs and search for stimulation patterns that violate biophysical constraints - uncovering diverse safety violations that conventional testing misses. #Neurotech #MLResearch #AIVerification

🚨Fuzzing the brain - automated stress testing for ML-driven neurostimulation🚨 As #MachineLearning begins to control electrical stimulation in neural interfaces, how do we know these models are safe? Paper in Journal of Neural Engineering: bionicvisionlab.org/publications... #BCI #neuroskyence

bionicvisionlab.orgFuzzing the brain: Automated stress testing for the safety of ML-driven neurostimulation | Bionic Vision LabWe propose a systematic, quantitative approach to detect and characterize unsafe stimulation patterns in ML-driven neurostimulation systems.

Most prior work treats safety narrowly, often by minimizing charge. But unsafe stimulation can take many forms: • physically impossible pulses • unsafe instantaneous currents • activating too many electrodes These are model outputs, so they need to be tested like software systems. #AISafety

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What if your strongest #ML model is brittle at one thing that really matters? Can it learn that behavior from a weaker but specialist model, even when they share no task, no data, and no architecture? My student Galen Pogoncheff explored this in our #ICLR2026 paper: 👉 arxiv.org/abs/2505.23933

arxiv.orgBIRD: Behavior Induction via Representation-structure DistillationHuman-aligned deep learning models exhibit behaviors consistent with human values, such as robustness, fairness, and honesty. Transferring these behavioral properties to models trained on different ta...

Bionic Vision Lab reposted

Just out in @nature.com BME: Our Review unpacks intracortical microstimulation: axons, not somas, drive activation; direct + indirect pathways shape perception; parameters interact with neuron type, layer, and network; long-term use limited by neural depression & tissue response. 🧠⚡ rdcu.be/eZbTz

rdcu.beNeural mechanisms underlying intracortical microstimulation for sensory restorationNature Biomedical Engineering - Intracortical microstimulation can elicit artificial sensations in persons who have lost sensation due to neurological injury or disease. This Review discusses...

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Presenting “Human in the loop optimisation for efficient intracortical microstimulation temporal patterns in visual cortex” again this afternoon at #SfN!! Come discuss! An amazing collaboration between the Biomedical Neuroengineering group at UMH and @bionicvisionlab.org

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Bionic Vision Lab reposted

What if retinal prostheses could speak the brain’s language? 👁️🧠🧪 Prof. Yossi Mandel and team built a hybrid implant that merges neurons and electrodes to restore high-acuity sight. New Data Drop interview ↓ www.bionic-vision.org/research-spo... #BionicVision #Neurotech #Blindness

bionic-vision.orgbionic-vision.org | Research Spotlights | Yossi MandelIn a new Advanced Functional Materials paper, Prof. Yossi Mandel and colleagues unveiled a hybrid retinal prosthesis that fuses living neurons with a high-density electrode array. By nestling human st...

Bionic Vision Lab reposted

Can Fruit Ninja train the #BionicEye? A new JoV paper finds that while participants improved with distorted “prosthetic” input, gaming-based training didn’t generalize to object recognition - hinting that rehab may need to stay task-specific. doi.org/10.1167/jov....

Bionic Vision Lab reposted

As federal research funding faces steep cuts, UC scientists are pushing brain-computer interfaces forward: restoring speech after ALS, easing Parkinson’s symptoms, and improving bionic vision with AI (that’s us 👋 at @ucsantabarbara.bsky.social). 🧠 www.universityofcalifornia.edu/news/thrilli...

universityofcalifornia.eduThrilling progress in brain-computer interfaces from UC labsUC researchers and the patients they work with are showing the world what's possible when the human mind and advanced computers meet.

🎓 Proud of our undergrad(!) Eirini Schoinas for leading this: bionicvisionlab.org/publications... 🧠 Human-in-the-loop optimization (HILO) works in silico—but does it hold up with real people? ✅ HILO outperformed naïve and deep encoders 🔁 A step toward personalized #BionicVision #EMBC2025

bionicvisionlab.orgEvaluating deep human-in-the-loop optimization for retinal implants using sighted participants | Bionic Vision LabWe evaluate HILO using sighted participants viewing simulated prosthetic vision to assess its ability to optimize stimulation strategies under realistic conditions.

🧠 Building on Roksana Sadeghi’s work: Calibrating retinal implants is slow and tedious. Can Gaussian Process Regression (GPR) guide smarter sampling? ✅ GPR + spatial sampling = fewer trials, same accuracy 🔁 Toward faster, personalized calibration 🔗 bionicvisionlab.org/publications... #EMBC2025

bionicvisionlab.orgEfficient spatial estimation of perceptual thresholds for retinal implants via Gaussian process regression | Bionic Vision LabWe propose a Gaussian Process Regression (GPR) framework to predict perceptual thresholds at unsampled locations while leveraging uncertainty estimates to guide adaptive sampling.