Bowles Lab

Announcing our plenary speakers for SCMND2027! View all of our confirmed speakers, Register, and Submit your abstract on SCMND.com SCMND2027: 19th-21st May 2027, Edinburgh, UK @ukdri.ac.uk #iPSC #neurodegeneration #organoids

Labby 4th Birthday to us! 🎂🎉🎂

We're BACK! 🥳 SCMND returns for 2027! 🎉🎉 Agenda, Speakers, Registration & Abstract submission now available on scmnd.com #iPSC #Organoids #Neurodegeneration #StemCell

The next Stem Cell Models of Neurodegeneration meeting is now loading... 🚨SAVE THE DATE!🚨 19th - 21st May 2027 Edinburgh, UK Registration & Abstract submission opening soon!

New pre-print from us! We compare two iPSC-microglia protocols, and take a look at the cell autonomous and non-cell autonomous effects of MAPT mutation: www.biorxiv.org/content/10.6...

Bowles lab Spring Thing 2026! We all went pottery painting - finished articles coming in a few weeks!

We had a super time at Curl Edinburgh for our lab Christmas party! So much fun - definitely recommend! See photo 4 for this year's lab gifts 🤩

We are looking for a bioinformatics postdoc to join our group! Apply here 👇👇👇 www.jobs.ac.uk/job/DPQ109/p...

New PhD position with us and @eastbio.bsky.social is now open, focused on developing novel iPSC- organoid models 👇👇👇 www.findaphd.com/phds/project...

Huge congratulations to lab postdocs Dr. Sousa & Dr. Lopez for each winning grants from @pspassociation.bsky.social! Such cool projects!!

🚨We're hiring!🚨 We're looking for a new postdoc to join our team, to lead a project focused on ELAVL4 subcellular localisation in iPSC organoids - check it out! 👇👇 elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Bowles lab Spring Thing 2025

From Tau2025 to #BNA2025 @britishneuro.bsky.social in Liverpool! We had the opportunity to host a session on Glial Mechanisms in Primary Tauopathy, sponsored by ARUK. Our PhD student Lois Keavey gave a super talk, followed by Dr. Aitana Sogorb-Esteve and Prof. Delphine Boche 🧠🧠🧠

We all had a super time at #Tau2025 this week! Learned a thing or two, made some new collabs and caught up with good friends! Thank you so much Rainwater Foundation, CurePSP, Alzheimer's Association & @pspassociation.bsky.social 😊

Day 1 of #SCMND2025 today! The Edinburgh weather was glorious and the science was incredible 😍😍 Looking forward to Day 2! @ukdri.ac.uk

Still thinking about #SCMND2025? Only 6 tickets left! 👇👇👇 scmnd.com #ipsc #organoids #dementia #neurodegeneration #neurons #microglia #astrocytes #oligodendrocytes

A reminder of the incredible line-up of speakers and panel discussants we have for the inaugural #SCMND2025 meeting next month. Registration CLOSES 7th March Find out more at scmnd.com @UKDRI #iPSC #neurodegeneration #organoids #stemcells #neuroscience

Meet our 5 ECR speakers, selected from >160 abstract submissions! You still have just over 2 weeks left to register for #SCMND2025! Head to 👉 scmnd.com for more info! @julien-klimmt.bsky.social @ukdri.ac.uk @cbdresearch.bsky.social @sheffielduni.bsky.social @ub.edu @lmumuenchen.bsky.social

A nice spotlight from us in @cp-trendsneuro.bsky.social, summarizing recent work in @natureneuro.bsky.social from the Zoghbi lab, showing tau phosphorylation & aggregation by TYK2 Original article👉https://tinyurl.com/wd4n2ewf Spotlight 👉https://tinyurl.com/3dwpw75m

Did you know, the venue for #SCMND2025 sits at the bottom of Arthur's Seat - an ancient extinct volcano? Come see some cool science AND take a stroll up a volcano, all in the same week - registration is still open! 👉https://scmnd.com/ #organoids #iPSC #stemcells #dementia

Wow! We have had such a fantastic response to our call for abstracts for #SCMND2025, we've been able to DOUBLE our poster capacity!!! Abstracts are closed, but Registration is still open! Come join us 🤗🤗🤗 👇👇👇 scmnd.com #ipsc #dementia #organoids

Not only are we bringing together the best #dementia #iPSC researchers, but we also want to platform the best resources and repositories at #SCMND2025. Interested in joining us @coriellinstitute.bsky.social @ncrad.bsky.social @isscr.org? 👇👇👇 scmnd.com

Haven't decided whether you're coming to #SCMND2025 yet? Perhaps Edinburgh in Springtime can convince you! Come join us for #iPSC, castles, and maybe a wee dram! Find everything you need to know at scmnd.com! #organoids #stemcells #neuroscience

Here's our incredible FULL LINEUP of speakers for #SCMND2025! Abstract submission closes Friday! scmnd.com @rikvanderkant.bsky.social @selinawray.bsky.social @carlescalatayud.bsky.social @rcasterton.bsky.social @annawilliamslab.bsky.social @sergiuppasca.bsky.social @neuralstemcells.bsky.social

🚨ONLY ONE MORE WEEK LEFT TO SUBMIT AN ABSTRACT!🚨 👇👇👇 scmnd.com #iPSC #stemcells #organoids #neurodegeneration #Alzheimers #FTD #ALS #Parkinsons #neuroscience #cureND #DZNE #UKDRI #ParisBrainInstitute @cbdresearch.bsky.social @edinunineuro.bsky.social

We need to improve the diversity of our iPSC models - we'll be discussing how we can do that and hearing from some fabulous speakers from around the world at #SCMND2025! @asapresearch.bsky.social Come and join the discussion - submit your abstract & register 👉 scmnd.com

We are so fortunate that #SCMND2025 is not only supported by UKDRI, but also by ARUK, Brain and Company of Biologists, as well as a host of other sponsors! Go to scmnd.com to find out more, submit your abstract & register! #ipsc #neuroscience #neurodegeneration #stemcell

Oooh look at that little green oligodendrocyte making its way through an organoid! #FluorescenceFriday #iPSC #organoids (Want to see more cool iPSC stuff? Come join us at #SCMND2025 in Edinburgh! Register at scmnd.com)

Neurons, astrocytes, microglia, oligodendrocytes, blood brain barrier, organoids, chips... we've got it all covered! 🧠 Check out our full list of speakers (and register to come see them) at scmnd.com! #iPSC #neuroscience #neurodegeneration #organoid #stemcells

ANOTHER exceptional 3D organoid models session at #SCMND2025? What a treat! Come join us in Edinburgh this March for some incredible science! Submit your abstract and register here 👉👉https://scmnd.com/ #iPSC #organoids #neuroscience #dementia #neurodegeneration #Edinburgh #UKDRI

More incredible speakers lined up for SCMND2025 - in the first of two sessions focused on 3D models of neurodegeneration! Submit your abstract before 31/01/2025 and register now! scmnd.com @cbdresearch.bsky.social @selinawray.bsky.social @annawilliamslab.bsky.social @edinunineuro.bsky.social

Come see our amazing plenary speakers at SCMND2025, March 26th-28th! Full agenda & registration are available at scmnd.com And hurry - abstract submissions are only open until the end of January!! 🏃‍♂️🏃‍♂️🏃‍♂️ #stemcell #iPSC #Neuroscience #Edinburgh #organoids

My son asked for a space cake, and a space cake he got!! 🚀 I'm very proud of it - it took a few evenings, and I made all of those chocolates myself from scratch! It's strawberry & vanilla with strawberry cream cheese frosting 😋 The kitchen is covered in glitter!

Really cool PhD opportunity with a colleague at the University of Strathclyde, developing an iPSC model of stroke on a chip: 👇👇👇 www.findaphd.com/phds/project... #PhD #iPSC #stroke #neuroscience

New toy for the lab arrived today! 🤗🤗🤗

Cool new paper from Edinburgh (@edinunineuro.bsky.social) using the FIRE mice to assess synaptic and neuronal properties in development in the absence of microglia. Maybe microglia aren’t as important as we thought? (lol jk don’t @ me glia people). 🧠🧪 rdcu.be/d5ru3

A great 2024 for the lab! So grateful to have such a wonderful team, doing such fun and interesting work! Really looking forward to what we will all accomplish together in 2025! 🤗🧠

I hope I'm not too late for #FluorescenceFriday! Here's one of our organoids from a recent pilot protocol we're testing out! (whole mount, cleared & imaged by light sheet)

Don't forget, the abstract deadline for SCMND 2025 is next month! Check out scmnd.com for more information! #ipsc #stemcells #neuroscience #Edinburgh #neurodegeneration #organoids

We had our lab Christmas party at The Anatomist escape room last night (highly recommend!) Super fun, we all escaped, then celebrated with a quiz and dinner 🤗🤗🤗

10 years after completing my PhD @cardiffuni.bsky.social, I'm on my way back for the first time to examine a viva and give a seminar in my old department! So honoured to have the opportunity for this full circle moment, and excited to visit both old friends and new!

Don't forget to register for Stem Cell Models of Neurodegeneration 2025 at scmnd.com !! Abstract submissions are open until the end of January 2025. We look forward to hosting you in Edinburgh 🤗 #iPSC #stemcells #neuroscience #neurodegeneration #dementia

Finally got this across the finish line! We made an isogenic panel of MAPT splicing mutation iPSCs that express high levels of endogenous 4R tau... ...and saw some cool stuff! 👇👇👇 tinyurl.com/38e5d6d2 Big thanks to supporters RCFneuro, Brightfocus, AFTD & UKDRI!

On my way to UCL to give a seminar on all things #tau and #iPSC! Looking forward to hanging out with the @marcaurelbusche.bsky.social and @selinawray.bsky.social labs 😊 Struggling with my enormous Edinburgh-weather-appropriate but London-inappropriate coat on the Piccadilly line though 🫣

The new @alzheimerssoc.bsky.social funded 🔬 VIDA DTC focuses on vascular & immune contributors to dementia. Join a collaborative PhD programme to advance understanding & treatments. 8 funded positions, and 14 projects to choose from. Apply by 20 Dec www.dementiaresearcher.nihr.ac.uk/phd-students...

An organoid Atlas? I'm listening... www.nature.com/articles/s41...

Interested in pursuing a PhD with Dr Ben Dickie, Dr Harry Pritchard, and me to explore the role of mural cells in Alzheimer’s disease? Feel free to apply or share this opportunity widely! www.findaphd.com/phds/project...

PhD opportunity: If you're interested in how astrocytes and the meninges talk to each other and how this is affected in dementia come do your PhD with us in Edinburgh (cc: Karen Horsburgh and Ingo Schiessl)! www.findaphd.com/phds/project...

Microglia are key players in neurodevelopment. It is thus essential to include them in brain organoids to study neurodevelopment, especially to study prenatal immune activation and how it impacts such a delicate process. Thrilled to have participated to this beautiful study. shorturl.at/7M9DU