Really cool preprint using precise stimulus timing to examine how theta oscillations affect mnemonic discrimination. I love this kind of clever behavioral approach. osf.io/preprints/ps...
Brock Kirwan
Brock Kirwan
@brockkirwan.com
Cognitive neuroscientist studying memory and decision making. How do we remember episodes and how do those memories help us make better decisions?
438 followers341 following138 posts
Brock Kirwan reposted
Dr. Andrew Persichetti is the Director of our Memory and Perception (MAP) Lab. His NIH-funded research studies how memory and perception systems support diverse cognitive functions. Visit our website to learn more about his impactful research projects and more! https://ow.ly/yoRo50ZZt8G
I loved this paper. The "triune brain" model is pretty silly, which is why I hate the term "limbic system". Is there a better anatomical term for subcortical structures including hippocampus and amygdala, though?
I just came across this paper by Cesario et al. that has one of the greatest titles ever: " journals.sagepub.com/doi/10.1177/...
New paper! We tested mnemonic discrimination at extended delays in healthy young adults and an amnesic patient and found that when target memories are strong similar lures are more likely to be mistakenly called "old" and less-similar lures are correctly rejected. However... doi.org/10.1002/hipo...
sensitive to target-lure similarity, even at 1-week delay in healthy young adults and after a 1-day delay in a patient with hippocampal damage. Many thanks to commenters on the earlier preprint and to the reviewers (sincerely, they made this version better). bsky.app/profile/broc...
Preprint day! Mnemonic discrimination is required to keep overlapping or similar experiences from interfering with each other in memory. We've done a lot of work on how this happens at short delays, but we've never examined this process at longer delays, like over a week osf.io/preprints/ps...
Thanks also to my coauthors including @brainscout.bsky.social and especially to the patient who emailed us while we were recruiting for the behavioral version of this study to "introduce us to [her] brain".
New paper! We tested mnemonic discrimination at extended delays in healthy young adults and an amnesic patient and found that when target memories are strong similar lures are more likely to be mistakenly called "old" and less-similar lures are correctly rejected. However... doi.org/10.1002/hipo...
when target memories are weaker (as in delay or hippocampal damage), the relationship between target-lure similarity and behavioral performance becomes much weaker. At first it looked like it went away all together, but in a 2nd exp. we added confidence measures and show that discrimination is still
Paper accepted at Imaging Neuroscience! Watch this space for links to the final open-access version. Also, thank you to the commenters on the original post--we incorporated some of your suggestions, which I think made for a better paper.
In honor of International Left-Handers Day, we have an updated preprint on scanning left-handed participants in fMRI studies. Although they're 11% of the population, we routinely screen LH people out of fMRI studies due to concerns about functional lateralization 1/n www.biorxiv.org/content/10.1...
Brock Kirwan reposted
📣 Assistant Professor of Teaching in Neuroscience at UCLA! ☀️ 🧠 Apply before Nov 9th recruit.apo.ucla.edu/JPF11315
Brock Kirwan reposted
Next AFNI Bootcamp: Oct 20-22, 2026! Classes cover: FMRI visualization, full subject-level processing, alignment, regression modeling, and quality control. Registration is free & open to both NIH and non-NIH researchers. Registration+details: afni.nimh.nih.gov/bootcamp Please share widely.
Brock Kirwan reposted
Our weekly seminar resumes tomorrow! Every Friday at Noon with pizza. Open to all. 111 NBS, 425 S Univ Ave @sas.upenn.edu Self-Control Conflicts Matter More than Self-Control Itself: Apathy, Socioeconomic Status, & Progress on Personal Goals Juan Pablo Bermúdez Philosophy, Univ of Southampton
In honor of International Left-Handers Day, we have an updated preprint on scanning left-handed participants in fMRI studies. Although they're 11% of the population, we routinely screen LH people out of fMRI studies due to concerns about functional lateralization 1/n www.biorxiv.org/content/10.1...
Huge thanks to my coauthors, Loriana Goulding (who led this research as her undergraduate senior thesis) and Isaac Hamm. Give it a read and let us know what you think! www.biorxiv.org/content/10.1...
In honor of International Left-Handers Day, we have an updated preprint on scanning left-handed participants in fMRI studies. Although they're 11% of the population, we routinely screen LH people out of fMRI studies due to concerns about functional lateralization 1/n www.biorxiv.org/content/10.1...
In honor of International Left-Handers Day, we have an updated preprint on scanning left-handed participants in fMRI studies. Although they're 11% of the population, we routinely screen LH people out of fMRI studies due to concerns about functional lateralization 1/n www.biorxiv.org/content/10.1...
Brock Kirwan reposted
Brock Kirwan reposted
This was my experience as an assoc editor at Frontiers as well. The system sent out auto-invitations in my name to random reviewers.
I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇
Brock Kirwan reposted
MindCORE DivE In 2026 October 9-11, 2026 Philadelphia DivE In brings undergrads interested in grad studies in mind sciences to Penn for mentoring. First-gen, low-income & those at schools with limited research resources strongly encouraged to apply by June 8: upenn.co1.qualtrics.com/jfe/form/SV_...
Brock Kirwan reposted
Our Institute, part of Jefferson Moss-Magee Rehabilitation and Thomas Jefferson University, is hiring for a tenure track faculty position! Applicants should have experience conducting research focused on human translational neuroscience & neurorehabilitation. https://ow.ly/yCBA50Z2eMl
Brock Kirwan reposted
Dr. Andrew Persichetti, Director of the Memory and Perception (MAP) Lab, studies how memory & perception systems support diverse cognitive functions using a combination of advanced methods, including fMRI, behavioral testing, and eye tracking. Learn more about his research: https://ow.ly/cTcc50YVvy4
Philly folks! Im giving a presentation tomorrow afternoon on study skills at the Kingsessing library. It’s targeted to students with ADHD, but all my tips are cognitive psychology based and will be helpful for anyone. @pennmindcore.bsky.social
Really cool study of hippocampal morphology changes across the lifespan. Analyses were based on publicly available MRI datasets, which included 2 from our lab hosted on openneuro.org. Really great to see our data continuing to be useful beyond our own publications.
Lamellar Normative Modelling of the Hippocampus Across the Human Lifespan | bioRxiv www.biorxiv.org/content/10.6...
New Preprint! Have you ever wondered if there's a relationship between the prestige of an author's institution and the sample size of their fMRI study? We did, so we did a systematic review of the memory fMRI literature and found the opposite of what we predicted www.biorxiv.org/content/10.6...
New Preprint! Have you ever wondered if there's a relationship between the prestige of an author's institution and the sample size of their fMRI study? We did, so we did a systematic review of the memory fMRI literature and found the opposite of what we predicted www.biorxiv.org/content/10.6...
Brock Kirwan reposted
Preprint day! Mnemonic discrimination is required to keep overlapping or similar experiences from interfering with each other in memory. We've done a lot of work on how this happens at short delays, but we've never examined this process at longer delays, like over a week osf.io/preprints/ps...
This whole project stemmed from a conversation with @brainscout.bsky.social several years ago. Sorry it took me so long to write it up!
Preprint day! Mnemonic discrimination is required to keep overlapping or similar experiences from interfering with each other in memory. We've done a lot of work on how this happens at short delays, but we've never examined this process at longer delays, like over a week osf.io/preprints/ps...
We found people forget! Which of course we were expecting (Ebbinghaus showed the forgetting curve in 1885). What's interesting is that as people forget the original targets, their responses to the similar lures change in interesting ways. When target memory is strong, people are able to discriminate
Preprint day! Mnemonic discrimination is required to keep overlapping or similar experiences from interfering with each other in memory. We've done a lot of work on how this happens at short delays, but we've never examined this process at longer delays, like over a week osf.io/preprints/ps...
New paper! Emerging adults with type 1 diabetes have been shown to have poorer executive control and working memory performance compared to controls. With Chad Jensen's lab we examined executive control in emerging adults with T1D using fMRI. 1/3
We found T1D S's demonstrated similar behavioral inhibition performance to controls but comparatively greater activation in several interconnected executive functioning-related brain regions. We did not find an association between hemoglobin HbAlc and executive function-related neural activation 2/3
These findings suggests that individuals with T1D likely exert greater neural "effort" in executive functioning-related brain regions to achieve similar levels of inhibitory control when compared to peers without T1D. Gift link: rdcu.be/e8nxE 3/3
Brock Kirwan reposted
Mind, Brain & Society WIP Thurs, March 19 3:30-5 PM (w/snacks & swag!) 200 Goddard, 3710 Hamilton Walk @upenn.edu To Do or Not to Do: How Goal Framing Shapes Behavioral Change Maya Enisman, PhD Postdoctoral Fellow, Annenberg Public Policy Center & Social Action Lab @appc.upenn.edu @asc.upenn.edu
Brock Kirwan reposted
Penn people can stop in anytime from 3-5 PM this Weds-Fri to make a sign/poster in our 200 Goddard Suite. We will have cardstock and large markers available. You bring the smart arguments.
PHILADELPHIA!!! Visit this link: fight2win.standupforscience.net/Philadelphia... to learn more about your local SATURDAY MARCH 7TH RALLY to TAKE BACK OUR SCIENCE! See map for location! Rally starts at 11AM!!! #March7Philadelphia #standupforscience #science #savescience!