Bruno Amaral

Bruno Amaral

@brunoamaral.eu

I want the web to be a better place. Communication Strategist, Creative Tinkerer. Weirdness and occasional posts in Portuguese. Helping Multiple Sclerosis research with @gregory-ms.com and https://brain-regeneration.com

543 followers402 following1.6K posts

Bruno Amaral
@brunoamaral.eu

"Bruno, deixaste de ser blogger?" Não, mas agora cada email que envio tem em média 4 mil caracteres. E esta semana foram mais de 10. Agora sou uma espécie de blogger escondido, acho eu

Bruno Amaral
@brunoamaral.eu

O whatsapp devia ter a opção de enviar a mensagem sem notificações. Para as coisas que não são importantes, que não valem o "DING!" E para aquelas surpresas boas de "olá, pensei em ti".

Bruno Amaral
@brunoamaral.eu

4 pessoas e 4 pontos chave na resistência pelo clima www.instagram.com/reels/DeOtvK...

instagram.com@baldiofilme on Instagram: "Joaquim, Carla, Aida e Francisco Este é o trailer do documentário BALDIO, onde acompanhamos quatro pessoas ligadas a momentos decisivos da ação e resistência ambiental em ...1,921 likes, 70 comments - baldiofilme on October 8, 2026: "Joaquim, Carla, Aida e Francisco Este é o trailer do documentário BALDIO, onde acompanhamos quatro pessoas ligadas a momentos decisivos da ...

Bruno Amaral reposted

Rui Martins
@ruimartins.bsky.social

🏠 O seu senhorio declara a renda que paga às Finanças? Se não sabe, ou se já desconfia que não, queremos ouvi-lo. Inquérito anónimo, demora poucos minutos. 👉 forms.gle/yaaeZx4vVE7w... #VizinhosEmLisboa #RendasLx

forms.gleInquérito Vizinhos em Lisboa: Declaração de Rendas às FinançasEste inquérito, promovido pela Vizinhos em Lisboa: Associação de Moradores, procura apurar a amplitude do fenómeno da não declaração de rendas às Finanças por parte de senhorios no concelho de Lisboa....
Bruno Amaral
@brunoamaral.eu

Help me break through the linkedin algorithm and repost this, please. We added a free tool for researchers and patients to get the best neurology research through their chatbots. www.linkedin.com/posts/brunoa...

linkedin.comGregoryAi now lets you connect any AI assistant to our website | Bruno AmaralThis can save precious time for research. We have over 54,000 papers and 17,000 clinical trials tracked. And you can get just the ones you need through your chatbot. The answer to cure neurodegenerat...
Bruno Amaral
@brunoamaral.eu

Love this 😁 it's the message you get in your downloads tab of Plexamp (Not sure what Plexamp is? Think spotify without the guilt. By the @plex.tv folks)

Bruno Amaral
@brunoamaral.eu

Em tempos escrevi emails de amor, hoje escrevo emails com as palavras microglias, oligódendrócitos, e mielina. Como se fossem quentes ditas ao ouvido. Imaginem — "Sossega, Coração! Disse eu quando te olhei para as microglias e me apaixonei"

Bruno Amaral
@brunoamaral.eu

Turno da noite, isto hj vai em português mesmo. Há duas grandes novidades em esclerose múltipla. Uma é um medicamento que já registou patente e ainda não tem ensaios. Outra é uma universidade do Canadá que transformou células estaminais em oligodendrócitos funcionais.

Bruno Amaral
@brunoamaral.eu

O primeiro é baseado num antigo medicamento anti malária. O segundo pode ajudar pessoas com EM a recuperar mobilidade. Tenho estado a fazer a minha parte partilhando com médicos e investigadores. Pq não tenho as ferramentas para validar e comunicar a pacientes o q ainda é muito incerto.

Bruno Amaral
@brunoamaral.eu

Já partilhei com a Soc. Portuguesa de EM e a equipa do hospital dos capuchos. E continuo a bater a portas e a fazer figas para que isto seja algo bom para todos. 🤞

Bruno Amaral
@brunoamaral.eu

This is the first trial I see of a new medicine aimed at remyelination for multiple sclerosis

GregoryAi@gregoryai.bsky.social

New clinical trial A Randomized, Double-Blind, Placebo-Controlled Phase 1/2a Trial of PRO-1562 in Healthy Adults and Adults With Multiple Sclerosis and Chronic Optic Neuropathy #ClinicalTrials #MultipleSclerosis #MSchat #Neurology

brain-regeneration.comA Randomized, Double-Blind, Placebo-Controlled Phase 1/2a Trial of PRO-1562 in Healthy Adults and Adults With Multiple Sclerosis and Chronic Optic NeuropathyPhase 1 will test single oral doses of PRO-1562 in healthy adult subjects to characterize the safety and the amount of drug that is absorbed into the body. Some subjects will have lumbar punctures performed to measure the amount of drug that crosses the blood-brain barrier sin...

Bruno Amaral reposted

Bruno Amaral
@blog.brunoamaral.eu.ap.brid.gy

Covid is still a fresh memory, and I am sitting in a café next to my flat. The barista is a friend from the Netherlands, and I have heard her say this quite a few times. I have agreed with her every time. The world is crazy and absurd, and I don't think it's getting any better. It's been four […]

brunoamaral.eu"The world is crazy, man"Covid is still a fresh memory, and I am sitting in a café next to my flat. The barista is a friend from the Netherlands, and I have heard her say this quite a few times. I have agreed with her every time. The world is crazy and absurd, and I don't think it's getting any better. It's been four or so years. That friend now has a wonderful baby and released an album. The world is still crazy, and it's not looking up. Today I feel worse than usual, and I'm taking refuge in memories from that time. I had been diagnosed a while back, but I could still walk. I had a corporate job that I thought would keep me somewhat safe. My favourite quote was "_I am and always will be the optimist. The hoper of far-flung hopes. And the dreamer of improbable dreams. — Doctor Who._ " I am scared of what is coming around the corner. The self bone-marrow transplant didn't stick, and I turned myself into a clinical trial. With ups and downs and trying to find clues for a dosage and regimen. These past few days, my symptoms have gotten worse, and as I type, I don't feel my fingers are quite right. Is this the disease spreading? Is the drug working? Will I be fit enough to get to my classes next week? Where do I cancel my subscription to the Anxiety++ plan? I worked across the summer on GregoryAi, and on more personal research of new drugs. What else could I do? The weather made it impossible for me to leave this white cell. It's weird. I am fighting a disease with a computer that can talk back, trying to gather the research that can one day help people like me. And I am reaching across most of the ParaSocial Media sphere for people who may help. I don't have much support apart from a few people I was lucky enough to find. My best friends are lobsters, baristas, copywriters, teachers, students and misfits from marketing agencies. (Meanwhile, my country's government decided to throw 1.8 million euros into the fire with another embarrassing AI project.) Four years ago, I didn't even accept the possibility that I would need a wheelchair. I had ideas, solutions to improve my search for a cure, hope that the answer would be in some digital pile of papers waiting for someone to connect the dots. I had blind hope. It is crazy how much has changed since then. Now I am stuck against a corner. Wondering why I can't get through to doctors and other researchers, for whom what I have been doing alone could be beneficial. I will hold that door open. I feel worn and tired, but I haven't given up.**** **"The world is crazy, man",** and we are all just trying to do the best that we can to make it a little better. <a href="https://mariechaplet.bandcamp.com/track/too-well-live">Too Well (Live) by Marie Chaplet</a> Too Well (Live), by Marie Chaplettrack by Marie ChapletMarie ChapletBandcamp New & Notable May 17, 2024
Bruno Amaral
@brunoamaral.eu

A bacteria can be a potential therapy for Multiple Sclerosis

GregoryAi@gregoryai.bsky.social

Brain Res. 2026 Sep 10:150544. doi: 10.1016/j.brainres.2026.150544. Online ahead of print. ABSTRACT Neuroinflammation driven by autoreactive T cells and activated glial populations underlies the pathogenesis of multiple sclerosis (MS), y... #MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky

brain-regeneration.comTRANQUIL attenuates autoimmune demyelination and suppresses neuroinflammatory signaling in experimental autoimmune encephalomyelitisBrain Res. 2026 Sep 10:150544. doi: 10.1016/j.brainres.2026.150544. Online ahead of print. ABSTRACT Neuroinflammation driven by autoreactive T cells and activated glial populations underlies the pathogenesis of multiple sclerosis (MS), yet current immunomodulatory therapies rarely restore durable...
Bruno Amaral
@brunoamaral.eu

Ran out of tokens for the Claude ̶s̶l̶o̶t̶ ̶m̶a̶c̶h̶i̶n̶e̶ Code and Cowork apps. Five years ago, this wouldn't be a problem, but now I am doing things at a level I could never have reached alone

Bruno Amaral reposted

Gina Trapani
@ginatrapani.org

Definitely remember posting about this on Lifehacker

WebDesignMuseum@webdesignmuseum.org

iGoogle in 2007 iGoogle was a customizable Google homepage (launched in 2005 and discontinued in 2013) that let users personalize their start page with widgets, news feeds, weather, email previews, and other web content.

Bruno Amaral
@brunoamaral.eu

Saying "we respect your privacy" to someone is not just a lie, it's a blatant affirmation that they don't. If they did, they would not use cookies or any other user-tracking analytics.

Bruno Amaral
@brunoamaral.eu

Did Chuck Norris inform God that he's now a Saint, or did he replace the Almighty? Asking because I have some praying to do and want to get it right

Bruno Amaral reposted

Jake Gold
@jacob.gold

Let's not shame people on X. People have bills to pay and network effects are powerful. Instead, encourage and enable "cross posting" to Bluesky like @thdxr.com does @toni.bsky.team Bluesky PBC should reach out to VIPs on X to offer simple solutions to cross posting, maybe even a free app/service.

Bruno Amaral
@brunoamaral.eu

Equal parts cool and annoying the way people are vibe coding plugins and hacks for their favourite apps. Obsidian, notion, and a bunch of others.