Citizens for Alternatives to Animal Research and Experimentation

NYU Langone Health mapped pancreatic cancer progression in human tumor cells, delivering human-relevant information for developing treatments that target mechanisms of tumor evolution. www.technologynetworks.com/cancer-resea...

Studying human patients, King's College London built a diagnostic test for “Broken heart syndrome” that may help patients avoid unnecessary invasive procedures. www.technologynetworks.com/proteomics/n...

University of Birmingham studied human brain tissue to reveal Parkinson's damage, revealing pathways that may be targeted for developing new therapies to treat Parkinson’s. www.technologynetworks.com/genomics/new...

Intero Biosystems developed intestinal organoids to replace animal tests and is getting them into the hands of companies to assess drug safety and disease treatment. techcrunch.com/2026/10/14/i...

Rice University used human cells and AI screening instead of animals to find leukemia treatments that killed cancer cells while sparing healthy cells in lab tests. www.technologynetworks.com/informatics/...

University of Birmingham found a neuroinflammation target using human brain tissue, showing human based research is more ethical and scientifically sound than animal testing. www.drugtargetreview.com/existing-dru...

UCLA reproduced anesthesia's brain effects in assembloids derived from human stem cells, addressing the longstanding question of how it affects the brain – impossible to do using animals. www.uclahealth.org/news/release...

University of Plymouth researchers used health records and AI to detect bladder cancer years earlier, showing how human-based research can advance diagnosis and treatment. www.technologynetworks.com/informatics/...

University of East Anglia researchers used human genetic data to link long Covid, ME/CFS and PTSD – human-relevant findings unlikely to be revealed through animal tests. www.technologynetworks.com/proteomics/n...

UCL researchers used a human 3D micro-bladder model with flowing urine to explain why UTIs keep coming back — finding phage therapy can clear bacterial reservoirs antibiotics miss. www.technologynetworks.com/immunology/n...

Arizona State University studied human blood and used AI to predict vaccine responses, providing human relevant findings that could transform clinical care. www.technologynetworks.com/biopharma/ne...

Brazilian scientists built a microfluidic device that simulates human tissue, offering a more accurate alternative to animal testing for drug and toxicity screening. agencia.fapesp.br/59188

Take action! Contact your Representative to co-sponsor the COMPACT Act, H.R. 10522, and end federally funded experiments on dogs and cats. Modern research methods are better. www.caareusa.org/end_taxpayer...

Imperial College London reviewed human data and found chronic inflammation tied to stress raises heart attack risk by 43%, while also identifying targets for earlier prevention. www.imperial.ac.uk/news/article...

MUSC Hollings Cancer Center built 3D human tissue models for pediatric bone cancer, addressing a gap where research on mice has failed to reflect how tumors spread in human bone. hollingscancercenter.musc.edu/content-hub/...

In one extraordinary week: the FDA embraced non-animal methods, NIH committed $88M to human-based research, and Congress introduced the COMPACT Act to end experiments on dogs and cats. www.caareusa.org/a_major_week...

In animal-free research, CU Anschutz found blood exosomes from shingles patients trigger nerve inflammation in human cells, offering an explanation for chronic post-herpetic pain. news.cuanschutz.edu/news-stories...

Finnish Institute for Health and Welfare traced the influence of dogs' microbes on childhood infections, human evidence from real environments. www.uef.fi/en/article/p...

King's College London ran the first NHS human trial of psilocybin for resistant depression, resulting in 40% remission vs 3% on placebo – animal-free research for real human results. www.kcl.ac.uk/news/promisi...

Tufts University used human neurons in 3D tissue scaffolds to track how herpes alters brain metabolism, a human based method offering insight animal testing cannot provide. www.technologynetworks.com/immunology/n...

LUMC grew mini inner ears from human stem cells, completing a missing cell type and offering a more precise way to study hearing loss than animal experiments. www.lumc.nl/en/news/2026...

Westlake University mapped over 13,000 proteins across human tissues and 25 cancer types, identifying 41potential cancer drug targets from human data rather than animal testing. www.technologynetworks.com/proteomics/n...

University of Surrey and Roehampton researchers studied human participants to link gut microbial pathways to brain GABA and glutamate levels, providing human-relevant data in a field that has traditionally been reliant on animal testing. www.surrey.ac.uk/news/gut-bac...

A*STAR's Genome Institute grew brain organoids from human stem cells to trace why autism looks different in each person, revealing detail animal testing cannot match. www.a-star.edu.sg/gis/press-re...

KAIST built a chip recreating a patient's glioblastoma cells and vascular barrier, predicting drug response through a human model animal testing cannot provide. www.news-medical.net/news/2026081...

University of Kansas Cancer Center researchers found that a simple blood test measuring ovarian reserve predicts chemotherapy benefit in breast cancer more accurately than age — human-based precision medicine that could spare 1 in 5 women unnecessary treatment. www.kumc.edu/about/news/n...

Harvard University grew human brain organoids from a blood draw and kept them alive for five years — long enough to track development, model disease, and test drugs in ways animal testing simply cannot replicate. www.fiercebiotech.com/research/ren...

Columbia University's human multi-organ chip tracked breast cancer cells colonizing engineered bone and lung tissue in real time — the kind of precision insight that animal testing cannot deliver. bioengineer.org/new-chip-rep...

The Netherlands Institute for Neuroscience used human brain tissue to identify a receptor linked to severe suicidal thoughts — a finding only possible through human-based research, and one that may point toward a future biomarker for suicide risk. nin.nl/news/researc...

The Broad Institute expanded its Cancer Dependency Map with 150 patient-derived 3D tumor organoids, uncovering drug targets invisible to conventional approaches — moving cancer research further from animal testing. www.broadinstitute.org/news/cancer-...

The largest-ever genetic study of fibromyalgia confirms it as a real nervous system disorder, not a psychosomatic one. Lunenfeld-Tanenbaum researchers found 26 risk regions, proving human-based research delivers what animal testing cannot. www.technologynetworks.com/genomics/new...

University of Birmingham researchers used AI and human tissue samples to identify 43 genes driving Crohn's fibrosis and linked gut microbiome shifts to disease progression — advancing treatment outcomes in ways animal research cannot. www.birmingham.ac.uk/news/2026/ai...

Flinders University reprogrammed skin cells from children with Sanfilippo syndrome into human brain cells, then used AI to identify nine approved drugs that improved cellular health — no animal testing involved, and clinical trials could follow quickly. www.technologynetworks.com/drug-discove...

Mice are the most widely used animals in research yet they are the least protected. They feel pain, fear and joy and help one another in a crisis. CAARE’s latest investigation reveals why we must not overlook the millions of mice used in laboratories. www.caareusa.org/sentient_vul...

Karolinska Institutet analyzed 7,308 human patients with Alzheimer's and atrial fibrillation, finding that modern blood thinners (NOACs) slowed cognitive decline — a human-relevant insight unobtainable from animal experiments. news.ki.se/blood-thinni...

The University of Rochester's human tissue chips just cleared an FDA regulatory milestone, moving closer to replacing animal testing for cancer immunotherapies — an area where animal testing has repeatedly failed due to fundamental differences in immune biology. www.eurekalert.org/news-release...

Ohio State's first U.S. psilocybin trial in veterans with treatment-resistant PTSD put 75% of participants into remission, demonstrating that human-based research, not inhumane and inapplicable animal experiments, can address this uniquely human condition. www.technologynetworks.com/drug-discove...

Harvard's Wyss Institute and Monash University are using gut-on-a-chip systems to study the human microbiome in ways animal testing simply cannot model, opening new doors for IBD and colon cancer research. www.technologynetworks.com/immunology/a...

The UK is investing £22 million ($30M USD) to replace animal testing with human organoids, AI, and lab-grown tissue models — a landmark government commitment to more ethical and scientifically accurate medicine development. www.gov.uk/government/n...

Vivodyne's robotic labs run 3 million human tissue experiments per year using AI, directly replacing animal testing that fails 90% of the time in clinical trials — and it's already catching unsafe drugs before they reach people. www.fastcompany.com/91589344/the...

VCU Massey researchers used human glioblastoma tumor samples to identify a molecular pathway keeping brain cancer stem cells alive — a discovery that points toward new treatments and demonstrates the power of human-based research over animal testing. www.technologynetworks.com/drug-discove...

The Wellcome Sanger Institute built a biobank of 256 human tumor organoids and used CRISPR to map cancer's genetic weak spots — human-based precision that animal testing cannot achieve. www.technologynetworks.com/cell-science...

NYU researchers built an AI test that predicts breast cancer recurrence from human pathology slides and clinical data, matching genomic tests in accuracy while delivering results faster, cheaper. www.technologynetworks.com/diagnostics/...

University Medical Center Groningen used human cardiac tissue and stem cell-derived heart cells to uncover and partially reverse the mechanisms behind PLN cardiomyopathy — the kind of precision insight animal testing is unlikely to provide. www.technologynetworks.com/biopharma/ar...

University of Chicago researchers found that SuperAgers — people in their 80s with memory rivaling 50-year-olds — don't simply carry low Alzheimer's genetic risk. www.uchicagomedicine.org/forefront/re...

Rutgers University used human brain imaging across 11 psychiatric diagnoses to show that brain network flexibility predicts symptoms better than diagnostic labels, pointing toward more precise, personalized mental health care. www.rutgers.edu/news/why-bra...

University of Miami researchers used human plasma proteomics and machine learning to identify a 19-protein signature predicting ALS onset years in advance, opening the door to prevention-focused trials. www.technologynetworks.com/diagnostics/...

A human blood study of 15,200 Europeans found that ultra-processed foods leave a distinct metabolic fingerprint tied to impaired fat processing and cellular stress, the kind of finding human-based research can deliver. newsroom.taylorandfrancisgroup.com/large-scale-...

Breaking: OHSU has proposed reducing its primate colony and transitioning toward human stem cell research, computational biology, and AI modeling — a landmark step away from animal testing and toward more ethical, human-relevant science. www.opb.org/article/2026...

German scientists used PET imaging in human volunteers to prove sleep resets overloaded brain connections, delivering direct evidence of how this process works in the living human brain, without cruel animal tests.