Cancer Genomics Consortium

The CGC Early Career Webinar is TOMORROW! Join us for The Negotiation Gene: Do You Have It? Learn practical strategies to negotiate salary, responsibilities & career opportunities with confidence. Featuring Dr. Kelly Quesnelle & Dr. Avni Santani. 📅 Oct. 28 | 12–1 PM ET 🔗 Register: buff.ly/gmrfVSG

Q47. A 47-year-old woman with colorectal cancer has a pathogenic PMS2 exon 13 nonsense variant by NGS. What is the next analysis? A. Allele-specific PCR B. MLPA C. OGM D. Long range PCR

Have you registered? Join CGC’s Early Career Committee on Oct. 28 for The Negotiation Gene: Do You Have It? Learn practical strategies for negotiating salary, positions, resources & career opportunities with Kelly Quesnelle, PhD, FAAPE, and Avni B. Santani, PhD, FACMG. Register: buff.ly/gmrfVSG

Help shape CGC 2027! Share your expertise through a scientific talk, panel discussion, or interactive workshop at the Annual Meeting in Seattle. 📅 Proposals due Nov. 16 🔗 buff.ly/e005glU

Q47. A 47-year-old woman with colorectal cancer has a pathogenic PMS2 exon 13 nonsense variant by NGS. What is the next analysis? A. Allele-specific PCR B. MLPA C. OGM D. Long range PCR Type your answer in the chat below and come back next week for the answer and explanation!

The CGC Early Career Webinar is almost here! Join the CGC Early Career Committee for The Negotiation Gene: Do You Have It? Featuring Kelly Quesnelle, PhD, FAAPE, and Avni B. Santani, PhD, FACMG 📅 October 28 | 10:00 AM PDT / 12:00 PM CDT / 1:00 PM EDT

🌟 CGC Volunteer Spotlight: Fang Fang, PhD! Fang is a CGC Trainee Member, Assistant Laboratory Director at Natera, and a volunteer with the CCGA Working Group. We’re grateful for her contributions to the CGC community! 🧬 #CGC #CancerGenomics

Tomorrow! Join Dr. David Scott as we dive into the evolving science of aggressive B-cell lymphoma. Explore molecular classifications and how they are advancing our understanding of the disease. 🗓️ October 13 | 12–1 p.m. ET Join the discussion: buff.ly/gw4QM8f #CancerGenomics #CGC

Coming up Tuesday! Join CGC on October 13 for a scientific discussion with Dr. David Scott on molecular classifications of aggressive B-cell lymphoma and their implications for understanding the disease. 🗓️ Tuesday, October 13 ⏰ 12–1 p.m. ET Register now: buff.ly/gw4QM8f

A year of growth. A vision for 2027. Explore CGC’s 2026 highlights and priorities for the year ahead in a letter from President Cate Randal Paschal, PhD, FACMG. 👉 buff.ly/CfXT0lI #CancerGenomics #CGC

🧬 Have an idea for CGC 2027? Invited Session Proposals are now open for the 18th Annual Meeting in Seattle! Submit ideas for scientific talks, panels, or interactive workshops. 📅 Deadline: November 16, 2026 Learn more and submit your proposal: buff.ly/CBfvBY6

📚 New CGC publication! The Somatic Overgrowth & Vascular Anomalies Working Group published a review in Genetics in Medicine on genetic testing and mosaic variants. 🔗 Read the full article: buff.ly/wbTOlKn

Q46: An 83-year-old man with DLBCL and a hx of prostate cancer has a TP53 path variant (VAF 45%) in blood. Family hx is negative. What’s the next step? A. Report + familial testing B. Report; likely de novo C. Test another tissue for mosaicism D. Test another tissue; likely CHIP

Registration is open! The Negotiation Gene: Do You Have It? Learn practical strategies for negotiating salary, positions, resources, responsibilities & career opportunities with confidence. Featuring Kelly Quesnelle, PhD, FAAPE & Avni B. Santani, PhD, FACMG 📅 Oct. 28, 2026 🔗 buff.ly/loo7fQj

The CGC Early Career Initiative has had a busy year of webinars, mentoring, networking, and outreach for the early career community. Next up: 🧬 The Negotiation Gene: Do You Have It? 📅 Oct. 28, 2026 Register today 👉️ buff.ly/loo7fQj

Registration is open! The Negotiation Gene: Do You Have It? Learn practical strategies for negotiating salary, roles, resources, responsibilities, and career opportunities with confidence. Featuring Kelly Quesnelle, PhD, FAAPE, & Avni B. Santani, PhD 📅 Oct. 28, 2026 🔗 Register: buff.ly/SxDK7r8

Webinar reminder: Join us Oct. 13, 12–1 p.m. ET, for a scientific discussion on molecular classifications of aggressive B-cell lymphoma with David Scott, MD, PhD. Register: buff.ly/gw4QM8f

Join us Oct. 13, 12–1 p.m. ET, for a scientific discussion on molecular classifications of aggressive B-cell lymphoma with David Scott, MD, PhD. 🧬 Register today: buff.ly/gw4QM8f

Q.45 Fusion NGS missed a classic t(11;14) in mantle cell lymphoma. FISH found it at 90%. Why did NGS fail to detect it? A. FISH tested a different sample B. No IGH-CCND1 chimeric RNA was made C. Tumor content too low D. NGS tested the wrong sample

🚨Last chance to apply! CGC is forming two new Working Groups focused on emerging priorities in clinical genomics. Bring your expertise, collaborate with colleagues, and help shape practical guidance for the field. Applications close Sept. 22 at 11:59 PM ET. #CancerGenomics

Help shape what comes next in clinical genomics. CGC is forming two new Working Groups focused on emerging priorities. Bring your expertise, collaborate with colleagues, and help develop practical guidance for the field. Applications close Sept. 22 at 11:59 PM ET. #CancerGenomics

Q.45 Fusion NGS missed a classic t(11;14) in mantle cell lymphoma. FISH found it at 90%. Why did NGS fail to detect it? A. FISH tested a different sample B. No IGH-CCND1 chimeric RNA was made C. Tumor content too low D. NGS tested the wrong sample Come back next week for the answer and explanation

Meet Hannah Wollenzien, a member of CGC’s Communications Committee! Hannah brings her communications expertise to the clinical genomics community while continuing to pursue her passion for dance as a teacher and professional performer. 💃 Learn more about Hannah 👉 buff.ly/WVbHjTT

🔬 CGC is forming two new Working Groups focused on important areas of clinical genomics. Bring your expertise, collaborate with colleagues, and help advance the field. Apply by Sept. 22 at 11:59 PM ET.

Q44. Mutations in which of the following genes are NOT associated with a diagnosis of essential thrombocythemia or primary myelofibrosis? A. JAK2 B. CSF3R C. MPL D. CALR

🔬 Help shape the future of CGC Working Groups. CGC members with expertise in cancer genomics, clinical genetics, laboratory diagnostics, informatics, and related fields are invited to apply for the new Working Group Oversight Committee. 📅 Apply by Sept. 14, 2026.

Q44. Mutations in which of the following genes are NOT associated with a diagnosis of essential thrombocythemia or primary myelofibrosis? A. JAK2 B. CSF3R C. MPL D. CALR Type your answer in the chat below and come back next week for the answer and explanation!

CGC members: Volunteers needed! 🧬 Join one of two new Working Groups focused on: • Genome Mapping & Long-Read Sequencing • Sporadic Colorectal Cancer Genomics 📅 Apply by Sept. 22, 2026 👉 Learn more: buff.ly/Y58T0d6

CLOSING SOON! Haven’t taken the AI Use in the Genetics Laboratory Survey yet? We want to hear from you, even if you don’t use AI. ⏱️ ~10 minutes 📅 Closes August 31, 2026 Your feedback helps us understand AI use across the genomics laboratory community. 👉 Take the survey: buff.ly/CfK5fEz

🎓 CGC 2026 Follow-Up Registered attendees can access recorded presentations through Dec. 31, 2026. Pursuing PACE or CME credit? Check your email for required steps, deadlines, and links. Thanks for being part of CGC 2026! See you in Seattle for CGC 2027!

🎓 Don’t forget to claim your CGC 2026 credits! If you attended CGC 2026 and are seeking PACE or CME credit, be sure to complete the required steps by the applicable deadlines. Check your email for complete instructions and links.

Thank you to our exhibitors and sponsors for helping make #CGC2026 a success! 📱 Download your Lead Retrieval contacts by Aug. 31. 📝 Complete the Exhibitor Survey by Aug. 28 to help shape the 2027 exhibitor experience. We look forward to partnering with you again at CGC 2027!

AI is transforming clinical genomics and cytogenetics. Help shape what's next by taking the **AI Use in the Genomics Laboratory** survey. 🧬 Benchmark AI adoption 💡 Support future funding ⚖️ Inform responsible AI regulation Takes about 10 minutes. 📅 Closes August 31, 2026. 👉 buff.ly/ln1MIAD

That's a wrap! Thanks to everyone for the awesome meeting! We look forward to seeing you all again next year! #CGCAnnual2026

Join Drs. Sharon Plon from Baylor College of Medicine, Marcy Richardson from Ambry Genetics, and Ryan Schmidt from the University of Southern California as they discuss, "Navigating variant classification in low penetrance genes and variants". #CGCAnnual2026

Join your colleagues for a coffee break in the exhibit hall #CGCAnnual2026

Join us for Platform Session 5 at #CGCAnnual2026! Discover how advanced genomic approaches improve diagnosis, risk stratification & management of hematologic malignancies. Learn about multi-platform profiling, germline testing & tumor–germline pairing for precision care.

Join your colleagues this evening at one of the optional #CGCAnnual2026 social activities. Don’t forget to take CGC with you by tagging us in your photos.

Join Drs. Wahab Khan from Dartmouth College, Stuart Scott from Stanford University, and Sherin Shaaban from University of Utah School of Medicine as they discuss, "Establishing Clinical Pharmacogenomics Testing: Assays, Implementation, and Resources". #CGCAnnual2026

Join us for Science Café Presentations from Vazyme International, Illumina, Promega, and @idtdna.bsky.social. We invite all attendees to visit the exhibit booths of our industry supporters throughout. #CGCAnnual2026

Unlock the power of bioinformatics in Platform Session 4 at #CGCAnnual2026! Learn about computational tools, LLMs for gene curation, centralized variant interpretation, and ML models integrating liquid biopsy for precision oncology.

Join us as we hear updates about the Cancer Genomics Consortium Working Groups from CGC President Dr. Fady Mikhail. #CGCAnnual2026

Join us as we hear updates about the Cancer Genomics Consortium Programs from Dr. Melanie Babcock. #CGCAnnual2026

Join us for Platinum Vendor Showcase by @labcorp.bsky.social talking about "Molecular residual disease: From detection to clinical application in solid tumors". We invite all attendees to visit the exhibit booths of our industry supporters throughout. #CGCAnnual2026

Join us for Platinum Exhibitor Showcase by Pillar Biosciences talking about "Rapid NGS Testing in Myeloid Malignancies: Pillar Biosciences Workflow, Use Cases, and Long FLT3-ITD Detection". We invite all attendees to visit the exhibit booths of our industry supporters throughout. #CGCAnnual2026

Join your colleagues for our annual Round Table Discussions. #CGCAnnual2026

Discover cutting-edge sequencing technologies in Platform Session 3: Emerging Technologies at #CGCAnnual2026! Learn about Hi-C vs. FISH for rearrangement detection in lymphoma, six-base cfDNA sequencing in retinoblastoma, RNAseq strategies, and long-read sequencing for leukemia & CNS tumors.

Join us for Science Café Presentations from Ultima Genomics, Covaris, Oxford Gene Technology, and Clear Labs. We invite all attendees to visit the exhibit booths of our industry supporters throughout #CGCAnnual2026