Chemical Science

Chemical Science

@chemicalscience.rsc.org

Flagship journal for @rsc.org. Open access, all topics in chemistry. chemicalscience-rsc@rsc.org 🌐 Website: rsc.li/chemscience

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Chemical Science reposted

Have you seen this new HOT article in Chemical Science? "When carbonyls beat aromaticity: An additive framework for predicting tautomeric preferences" by Lucas Araujo, Felipe Fantuzzi, Pierre M. Esteves and Thiago M. Cardozo. Read this exciting new research for free here: doi.org/10.1039/d6sc...

Have you seen this new HOT article in Chemical Science? "When carbonyls beat aromaticity: An additive framework for predicting tautomeric preferences" by Lucas Araujo, Felipe Fantuzzi, Pierre M. Esteves and Thiago M. Cardozo. Read this exciting new research for free here: doi.org/10.1039/d6sc...

HOT in Chemical Science! "Emergent integration of the amine scrubbing method into photocatalytic CO2 reduction" by Naoki Hosokawa, Shunya Uno, Hiroharu Watanabe, Osamu Ishitani. ❗Captured atmospheric CO₂ is converted directly to formic acid at room temperature 🔗 doi.org/10.1039/d6sc...

🔥HOT🔥 new research in Chemical Science: "Heme sequestration and signaling in molecular condensates" by Ananya Mishra, Andrea E. Gallio, Emma L. Raven, Avinash J. Patil, Stephen Mann. 👉 Membraneless droplets support competitive heme sensing and logic 🔗 doi.org/10.1039/d6sc...

New and HOT in Chemical Science! 🔥 "Synthesis and structure of the mercury hydride compound, [TismPriBenz]HgH: a complete series of congeneric terminal hydride compounds of zinc, cadmium and mercury" by Matthew Hammond, Josef D. Daniels and Gerard Parkin. 🔗 doi.org/10.1039/d6sc...

Issue 40 of Chemical Science is here! 🎉 This week's front cover is from Eric Schwegler, Ute A. Hellmich et al. and showcases their paper "Inhibitor fluorination pattern modulates protein surface dynamics and chemically induced dimerization". Read the work at: doi.org/10.1039/d6sc...

📈 Trending in Chemical Science! “Exploring chemical space for iridium(iii) complexes: a direct-to-biology (D2B) approach to identifying anticancer and antibacterial agents” by Timothy Kench, Heather J. Kulik, and Ramon Vilar et al. Read it for free here: doi.org/10.1039/d6sc...

This week's Chemical Science Pick of the Week is "Stereodivergent Csp3–Csp3 bond construction via Lewis base/iridium cooperative catalysis: a modular synthesis of tertiary fluoride-containing stereodiads" by Professor Thomas N. Snaddon and colleagues! 🔗 Read for free: doi.org/10.1039/D6SC...

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The method combines α-fluorinated C1-ammonium enolates and π-allyl iridium intermediates, with each catalyst independently controlling the configuration of one stereocentre, enabling precise control over both relative and absolute stereochemistry.

Notably, readily accessible racemic α-fluoro esters are converted into single α-fluoro C1-ammonium enolates, providing a modular route to structurally complex fluorinated molecules. Discover related work in our themed collection on organofluorine chemistry: blogs.rsc.org/sc/202...

This week's Chemical Science Pick of the Week is "Stereodivergent Csp3–Csp3 bond construction via Lewis base/iridium cooperative catalysis: a modular synthesis of tertiary fluoride-containing stereodiads" by Professor Thomas N. Snaddon and colleagues! 🔗 Read for free: doi.org/10.1039/D6SC...

A stereodivergent Lewis base/iridium cooperative catalytic strategy has been developed for the construction of tertiary fluoride-containing stereodiads through Csp³-Csp³ bond formation.

📈 Trending in Chemical Science! “One-dimensional covalent organic frameworks with spatially separated electron–hole distributions for dual-channel charge transfer to enhance photocatalytic H2O2 production” by Guo-Fang Jiang, Yubin Fu and Xin Zhao et al. Read it free here: doi.org/10.1039/d6sc...

New HOT article from Professor Stefan Matile and colleagues in Chemical Science! "Traceless trimethyl-lock translators for thiol-mediated uptake of native proteins as covalent constructs" Traceless TMU translators enable efficient cytosolic delivery of native proteins. 🔗 doi.org/10.1039/d6sc...

✨ New and HOT in Chemical Science! "In situ reduction of CO2 forms surface redox mediators on nanoparticle catalysts" by David W. Flaherty and colleagues. 👉 CO₂-derived surface species double H₂O₂ production and boost selectivity to 90% 🔗 Read for free: doi.org/10.1039/d6sc...

Check out this Chemistry World profile of a sulfinate–azide hybrid reagent for sequential radical fluoroalkylation and click reaction recently reported by Petr Beier et al. in this Chemical Science article: doi.org/10.1039/d6sc...

Chemistry World@chemistryworld.com

Chemists have developed a reagent that adds a fluoroalkyl group while leaving molecules primed for further modification with click chemistry. The work reflects growing interest in reagents that can reduce the number of steps needed to build complex molecules.

🎉 Issue 39 of Chemical Science is here! 🖼️ This week's front cover is from Payton E. Lowrey and Ku-Lung Hsu and highlights their paper "Liposomes can directly modulate serine hydrolase activity and lipid metabolism independent of cargo". 🔗Read for free here: doi.org/10.1039/d6sc...

🔥New and HOT in Chemical Science!🔥 "Unlocking catalytic asymmetric transformations of sulfilimidoyl fluorides toward chiral sulfinimidate esters" by Jin Zhang, Gu Zhan, Bo Han and colleagues. ✨ Dynamic kinetic resolution unlocks stable, bioactive S(IV) esters 🔗 Read: doi.org/10.1039/d6sc...

The Chemical Science Pick of the Week is "Main-chain programming of poly(aryl ether ketone)s enables superior high-temperature dielectric energy storage” by Honghong Gong, Yunchuan Xie, Zhicheng Zhang et al. from Xi’an Jiaotong University. Read it for free: doi.org/10.1039/d6sc... #ChemSciPicks

📈 Trending in Chemical Science! “Heterometallic ion-regulated full-color gold nanoclusters for multicolor bioimaging and circularly polarized luminescence” by Yaguang Yin, Gan Zhao, Fanfan Yu and Honglin Liu from Hefei University of Technology. Read it for free here: doi.org/10.1039/d5sc...

Chemical Science reposted

🧪 Carboxylic acids are abundant, stable, and widely available building blocks in orgchemistry. Turning them into reactive radicals through decarboxylation offers an attractive way to form new carbon–carbon bonds under mild conditions... 🧵 #research #photochem #electrochem #orgchem #compchem

Chemical Science reposted

We had a great panel of experts celebrating the work of Henri Kagan & Kensō Soai on Friday. Don’t worry if you missed the webinar exploring all things Nobel prize in chemistry, you can catch up on the recording here: #ChemSky #NobelPrize #ChemNobel @rsc.org www.chemistryworld.com/webinars/nob...

chemistryworld.comNobel prize in chemistry 2026: ReactionJoin us for an exclusive look at the science behind the Nobel prize in chemistry 2026

New and 🔥HOT🔥 in Chemical Science! "C–H magnesiation of unactivated arenes by a bulky β-diketiminato magnesium n-butyl complex" by Louis J. Morris, Michael S. Hill, Claire L. McMullin and colleagues. 👉Bulky Mg complex enables direct arene functionalisation! 🔗doi.org/10.1039/d6sc...

Have you seen this new HOT article? ✨ "Epitaxial Ga/ZSM-5@S-1 core–shell zeolites boost CO2-coupled propane aromatization" by Jian Liu, Weiyu Song and colleagues. 💡 Spatially separated Ga sites enhance CO₂ use and reveal a new oxygen-transfer pathway. 🔗 doi.org/10.1039/d6sc...

Exploring: ✅ Digital sustainability data sharing across value chains ✅ Bio-based and biodegradable polymer innovation ✅ UK and EU sustainability policy and regulation ✅ Feedstocks, resilience and the carbon transition ✅ What it will take to create successful markets for sustainable products

Join industry leaders, researchers, innovators and policymakers from across the UK and Europe on 22 October in London to explore what it will take for next-generation PLFs to enable sustainable and resilient industries operating within planetary boundaries by 2040.

Popular and trending in Chemical Science! 📈 "Red light mediated energy transfer catalysis via stable organic radicals" by Andrew Brian Pun and colleages. 💡 Stable organic radicals enable versatile red-light photocatalysis without rare metals Read for free: doi.org/10.1039/d6sc...

We're pleased to share the winners of the poster awards sponsored by Royal Society of Chemistry journals at the 22nd Annual Tri-institutional Chemical Biology Symposium! chembio.triiprograms... Prizes were contributed by Chemical Science, RSC Chemical Biology and Organic & Biomolecular Chemistry.

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Emily Scheib won received the prize from Organic and Biomolecular Chemistry, for "Inhibition of ABCB1 and ABCG2 to enhance drug delivery across the blood-brain barrier". Our congratulations to all of the winners!

We're pleased to share the winners of the poster awards sponsored by Royal Society of Chemistry journals at the 22nd Annual Tri-institutional Chemical Biology Symposium! chembio.triiprograms... Prizes were contributed by Chemical Science, RSC Chemical Biology and Organic & Biomolecular Chemistry.

This research showcase is organised by Memorial Sloan Kettering Cancer Center, The Rockefeller University, and Weill Cornell Medicine in New York City. The winner of the award from RSC Chemical Biology is Theodore Yassa, for “Protein-Protein Interaction Discovery in Human Solid Cancer Biopsies”.

Issue 38 of Chemical Science is here! #ChemSciCovers Featuring work from Hao Li, Yongliang Tang, Yuanzheng Chen and colleagues! "A closed-loop framework for descriptor-empowered exploration of high-activity Co-based quaternary molten alloy catalysts for methane pyrolysis" doi.org/10.1039/d6sc...

Chemical Science reposted

Join your community to discover cutting‑edge innovation and explore how emerging materials and digital tools are shaping the future of sustainable PLFs solutions– secure your place now. Registration closes on 12 October 2026. Secure your place now: rsc.li/plfsummit2026 #ChemSky