Child Health Research Foundation

Child Health Research Foundation

@chrfbd.bsky.social

Preventing infections, saving lives and building scientists to improve child health through evidence and advocacy. #forBangladesh #inBangladesh #withBangladesh

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1/ CHRF offers Whole Exome Sequencing (WES) to support the investigation of complex and undiagnosed genetic conditions. By combining next-generation sequencing with bioinformatics analysis and clinical interpretation, our service helps identify and classify genetic variants.

1/ At the Wellcome Mid-Career Researcher Meeting in London, a photograph from rural Mirzapur, Bangladesh, was featured in the event’s virtual gallery, Research in One Frame. It captured a simple but meaningful moment from CHRF’s ongoing research.

2/ In the photograph, nine-month-old Abir sits calmly on his mother’s lap as our team prepares to collect his sample to test for respiratory syncytial virus (RSV), a virus that can cause respiratory diseases such as pneumonia.

3/ This photograph captures the first step in a much larger effort to understand why RSV causes more severe disease and higher mortality among children in low- and middle-income countries like Bangladesh. Each visit brings us closer to finding answers.

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3/ This ELISA test measures the antibodies children develop after vaccination. Antibodies are proteins our bodies produce to help fight infections like pneumonia and meningitis, and measuring them helps us understand how children respond to the vaccine.

1/ Bacteriophages, or phages, are viruses that infect bacteria. CHRF scientists have spent the past several years collecting and characterizing phages that infect Salmonella Typhi, the bacterium responsible for typhoid fever, from environmental water samples across Bangladesh.

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6/ Meanwhile, our own research at CHRF continues to reveal surprising diversity among Typhi phages, including the discovery of phages that can infect bacteria without relying on the capsule previously thought to be essential for infection.

1/ Bacteriophages, or phages, are viruses that infect bacteria. CHRF scientists have spent the past several years collecting and characterizing phages that infect Salmonella Typhi, the bacterium responsible for typhoid fever, from environmental water samples across Bangladesh.

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1/ Bacteriophages, or phages, are viruses that infect bacteria. CHRF scientists have spent the past several years collecting and characterizing phages that infect Salmonella Typhi, the bacterium responsible for typhoid fever, from environmental water samples across Bangladesh.

2/ What began as an effort to develop affordable tools for tracking typhoid in our communities has grown into a diverse biobank of phages, opening new opportunities to understand how these viruses interact with bacteria, and why some bacterial strains resist infection.

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3/ She also spent time with our Building Scientists for Bangladesh community, hearing how the initiative grew from a simple question asked by young girls who wanted to know whether they, too, could become scientists.

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3/ Between all the questions, we also got to hear about their dreams. Some want to explore the tiny world of microbes, while others dream of reaching all the way into space. Some are still figuring out which path to take, but one thing seemed certain: they want science to be part of their future.

4/ This visit was part of Stream 2 of Building Scientists for Bangladesh, where we open our labs to bring young people closer to science. We loved having Sunnydale in our labs, and if you would like your school to visit us next, email us at buildingscientists@chrfbd.org !

2/ They explored our labs, met our scientists, and saw a little of what science looks like beyond their textbooks. The afternoon ended in conversation with Dr. Senjuti Saha, and the questions kept coming: Can diseases ever truly be eradicated? What does a career in science actually look like?

1/ A decade of respiratory health research, capacity building, and partnership came together at the final RESPIRE (NIHR Global Health Research Unit on Respiratory Health) Annual Scientific Meeting in Kuala Lumpur, Malaysia.

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1/ A decade of respiratory health research, capacity building, and partnership came together at the final RESPIRE (NIHR Global Health Research Unit on Respiratory Health) Annual Scientific Meeting in Kuala Lumpur, Malaysia.

3/ Since 2018, RESPIRE has been a valued research partner of CHRF. Representing CHRF at the meeting were Dr. Mohammad Shahidul Islam, Associate Scientist, and Hakka Naziat, Research Investigator, who shared CHRF’s work and contributed to discussions on research capacity building in Bangladesh.

From vibrant plates to colourful tubes, microbiology has its own little palette. Here's a glimpse into the colourful side of microbiology, through the lens of our Building Scientists for Bangladesh (BSB) trainees at CHRF!