Christopher Rose

30 May

I already landed in Sam Diego and had a great day at Legloland today. Check out these #ASMS2026 presentations Genentech and the Proteomics department from the recently formed Translational Genomics and Proteomics Center. Very proud of all members of the department for their showing this year!

Excited to share our new preprint on MIRA-MS — a real-time AI-guided acquisition strategy for deeper immunopeptidomics!

Susan Klaeger@susanklaeger.bsky.social

Excited to introduce MIRA-MS, a real time artificial intelligence prediction tool for analysis of MHC peptides! If you are at ASMS, check out poster 459 on Thursday. www.biorxiv.org/content/10.6...

biorxiv.orgbiorxiv.org

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⚡ MSFragger-RTS — fast, fragment-indexed real-time search including nuORF databases 🤖 Salud — a Prosit-derived AI model for real-time fragmentation + retention time prediction 🔬 Real-time FDR rescoring UI to improve canonical vs. nuORF assignments

In ccRCC cell lines, MIRA-MS quantified 97–107% more non-canonical peptides and 45–89% more canonical peptides vs. standard acquisition. Great collaboration with @nesvilab.bsky.social

Excited to share our new preprint on MIRA-MS — a real-time AI-guided acquisition strategy for deeper immunopeptidomics!

Susan Klaeger@susanklaeger.bsky.social

Excited to introduce MIRA-MS, a real time artificial intelligence prediction tool for analysis of MHC peptides! If you are at ASMS, check out poster 459 on Thursday. www.biorxiv.org/content/10.6...

biorxiv.orgbiorxiv.org

Non-canonical (nuORF) HLA peptides are promising cancer targets, but their low abundance makes them hard to find. MIRA-MS combines:

25 Nov 2025

I am looking for a PostDoc to join my group at Genentech to drive the development of proteomics technologies to fuel target and therapeutic discovery and development. Check out the link below! careers.gene.com/us/en/job/20...

25 Jan 2024

As of now the only way to remove 126 is to take reporter ions to ion trap and isolate there. We did that in our Nature Methods paper, but you lose some 127. Other way would be to raise RF amplitude enough to create a low mass cutoff. Interesting idea, but would require some instrumentation changes.

PastelBio@pastelbio.bsky.social

News in Proteomics Research blog post | SCOPE-X - Boost your multiplex single cell relative signal with this one trick! proteomicsnews.blogs... --- #proteomics #prot-other

31 Oct 2023

Check out this Postdoctoral position! Two great labs at Genentech to be co-mentored by. You get to work in our department. You can see me as much (or as little) as you want!

PastelBio@pastelbio.bsky.social

Postdoctoral Fellow - Proteomics of Neurodegeneration, Ori/Bingol Labs - South San Francisco - Genentech | www.theladders.com/j... --- #proteomics #prot-jobs

19 Oct 2023

Excited to share the publication of a large collaborative effort at Genentech to discover shared cancer neoantigen neoepitopes. From 47 cancer neoantigens and 15 HLA alleles we discovered 86 neoepitope-HLA pairs, 65 were novel at acceptance - check it out! www.nature.com/articles/s41...