Carolina Tropini (TropiniLab@UBC)

Carolina Tropini (TropiniLab@UBC)

@ctropini.bsky.social

Assistant Professor at the University of British Columbia studying the gut microbiota and abiotic environment in health and disease. http://tropini.microbiology.ubc.ca

265 followers79 following6 posts

Carolina Tropini (TropiniLab@UBC)
@ctropini.bsky.social

Excited to share our latest publication, led by Dr. Ellie McCallum and Juan Burckhardt! bit.ly/4kfzQaf You can access the article for free here: authors.elsevier.com/a/1mWb4L7PXu... And more information is available on the updated preprint: www.biorxiv.org/content/10.1...

bit.lyGlowing bacterial sensors detect gut illness in mice before symptoms emergeUBC researchers have engineered gut bacteria that dim their fluorescent glow in the presence of illness.
Carolina Tropini (TropiniLab@UBC)
@ctropini.bsky.social

Sharing exciting work led by PhD students McCallum and Burckhardt! We created a new series of syn bio tools in Bacteroides to create non-invasive, real time and sensitive in vivo gut biosensors. www.biorxiv.org/content/10.1...

biorxiv.orgExpanding the Bacteroides synthetic biology toolkit to develop an in vivo intestinal malabsorption biosensor.The human gut is a highly dynamic physical environment where perturbations - including factors such as acidification, oxygenation, and particle concentration (osmolality) - can influence microbiota co...
Carolina Tropini (TropiniLab@UBC)
@ctropini.bsky.social

Excited to share our latest preprint led by Dr. Hunter! We show that osmotic shifts, common in the gut, alter T4 phage-E. coli evolution. High osmolality promotes fitness but selects for mucoid, weakly phage-resistant E. coli, with implications for phage therapy! biorxiv.org/content/10.1...

biorxiv.orgOsmotic conditions shape fitness gains and resistance mechanisms during E. coli and T4 phage co-evolutionBacteriophages, or phages, are viruses that infect bacteria and offer a promising approach to combating antimicrobial resistance in the gut by selectively targeting harmful bacteria while preserving t...
Carolina Tropini (TropiniLab@UBC)
@ctropini.bsky.social

Excited to share our latest publication by Adel Yavarinasab et al!

Ákos T Kovács@evolvedbiofilm.bsky.social

Electrogenic dynamics of biofilm formation: Correlation between genetic expression and electrochemical activity in Bacillus subtilis Biosensors and Bioelectronics from @ctropini.bsky.social www.sciencedirect.com/science/arti...

sciencedirect.comElectrogenic dynamics of biofilm formation: Correlation between genetic expression and electrochemical activity in Bacillus subtilisBiofilms are structured microbial communities, known for their electron transfer properties, which are essential for metabolic processes and microbial…

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