David Seminowicz

we've got an outstanding lineup this year. join us!

Call for Posters! Deadline: November 16, 2026 Visit canadianpainsociety.ca/posters for more details 🍁 L’appel à soumission d’affiche est maintenant ouvert Date limite : 16 novembre 2026 Visitez canadianpainsociety.ca/fr/posters pour en savoir plus

Alpha-range neural oscillations are associated with multiple dynamic brain networks https://www.biorxiv.org/content/10.64898/2026.10.12.758569v1

We are making big moves in Neuroscience and Center for Advanced Pain Studies in UTD School of Behavioral and Brain Sciences. We have two tenure track positions just opened up for medicinal chemistry hires in our Department. Job posting is here: jobs.utdallas.edu/postings/32994

New preprint alert, with massive congratulations to Andy Cooper, Greg Weir, and others! #PainResearch @weirlab.bsky.social Precision cell-state silencing of injured afferents alleviates spontaneous neuropathic pain www.biorxiv.org/content/10.6...

A new fMRI study just out on precision functional mapping of imagined and experienced pain, led by Michael Sun (Sun et al., 2026, Nature Communications). How strongly does imagining pain activate nociceptive representations in the brain? doi.org/10.1038/s41... Thread below 👇

6/6 Bottom line. #1. Claims from our group and others re Ce/CeA recruitment are sound. #2. Use unsmoothed data for assessing amygdala engagement, esp for nuclei claims. Be mindful of “artifact”/mixing at the dorsomedial edge. Axial slices informative. A careful, valuable preprint! Kudos to authors.

www.biorxiv.org/content/10.6... - 1/6 Signal from the basal vein of Rosenthal (BVR) distorts amygdala activation. We read it closely. Great work from an all-star team of rigorous scientists! BUT a few “BOLD” claims in the Abstract/Discussion go beyond the data. 🧵

check out this very nice work. mariya was a trainee/RA in my lab, but decided for her PhD to study pain in flies instead of humans. she came up with some cool new assays and important discoveries.

new work from the lab using rTMS, TMS-EEG and a prolonged pain model and getting us a little closer to understanding the mechanisms behind alpha and pain, with implications for individualized neuromodulation interventions for chronic pain www.ovid.com/10.1097/j.pa...

Excited to see our fMRI paper is out, led by Itamar Kahn’s lab. Our grad students, Amir Lawen and Bella Succi, in collab with Darcy Peterka, built a setup for simultaneous fMRI and dopamine fiber photometry in awake behaving mice. We learned some new biology too. www.science.org/doi/10.1126/...

Brenda Milner.

Out now in @natmed.nature.com: we pooled self-reported pain data from 6M+ people in 118 countries across the lifespan. Most pain types climb steeply before 55, women report more pain, and late-life pain is highest in low-HDI regions. Led by @mattfillingim.bsky.social www.nature.com/articles/s41...

Time for a special announcement I've been hinting at all semester For the past ten years we have been developing an online course on quantitative MRI, and we are ready to share it with the world. To register click the link below or scan the QR code 1/2

PAIN Reports PLACEHOLDER DO NOT DRAFT

Faculty position at the University of Toronto 👇 jobs.utoronto.ca/job/Toronto-...

Today is the National Day for Truth and Reconciliation where we remember the survivors of Canada’s residential school systems and the children who never returned home, their families and their communities, and the lasting impacts of this colonial system.

👉 Tenure-track opening in neuroscience @crchum.bsky.social @umontreal.ca crchum.carrieresante.gouv.qc.ca/poste/profes...

Wonderful interview of @drjkhokhar.bsky.social on a paper that changed his life.

I am thrilled to announce that we have a new computational neuroscience position available in our Department of Neuroscience and Center for Advanced Pain Studies: jobs.utdallas.edu/postings/32726

neuromarkers.io : Browse, view, and download fMRI neuromarkers, population-level predictive brain models that can be applied to new studies and populations

uhoh maybe

JCI - Myotonic Muscle Activity Drives a Persistent Pain State Responsive to NaV1.8-directed Analgesics www.jci.org/articles/vie...

New publication using Lead-DBS: In this article by Huang et al., the authors mapped pain-related networks using rapid stereo-EEG to enable personalized multinodal stimulation for refractory facial pain. Check out the paper here 👇👇 https://doi.org/10.1016/j.brs.2026.103176

Our SORDINO paper is available @natneuro.nature.com. I hope it will prove useful to the fMRI community. www.nature.com/articles/s41... Our earlier digest: bsky.app/profile/shih... News & Views by @shemesh-lab.bsky.social: www.nature.com/articles/s41... Use SORDINO in your lab: camri.org/SORDINO

1/ Six years in the making! Our preprint on SORDINO fMRI is out. We're sharing the raw data and sequence to facilitate brain-wide mapping in awake, behaving rodents. If this could be useful to your colleagues and friends, please help spread the word! www.biorxiv.org/content/10.1...

PAIN Reports PLACEHOLDER DO NOT DRAFT

Free, downloadable #neuroimaging patterns you can download and apply to your brain imaging studies. Neuromarkers (neural ‘signatures’), atlases, and meta-analysis maps on Github: github.com/canlab/Neuro...

Professor Sisyphus Begins a New Semester “Professor Sisyphus finally figured out how to plagiarism-proof his writing assignments. Immediately, computers learned how to instantly write B+ student papers.” www.mcsweeneys.net/articles/pro...

YOUR LIFETIME % risk for various brain conditions* 🔥 diseases with larger effects on the brain tend to be less common, which I explain here youtube.com/watch?v=3iWp... 🔥young-onset often have higher lifetime risk 🔥yes research funding is not proportionate *slide I made for an upcoming ENIGMA talk

We also show 2 cool new findings: 1. that innocuous stimulation (the thermal grill) causes sensitization in responders and nonresponders 2. that moderate cold stimuli (7°C) cause sensitization

📣 Check out the latest paper from our lab out now in @pnas.org 📣 We show that nociceptive sensitization can occur in the absence of pain stimulation. We use the thermal grill illusion, and show that nonresponders show greater central sensitization (secondary hyperalgesia) than responders.

youtu.be/DIOHVW4IWrE 📢Here's the next interview in our new #PeprPartnership series: "A Few Minutes With ---" We caught up with Dr. David Walton of @westernknowpain.bsky.social and the CanSpine Research Group at @westernuresearch.bsky.social.

Check out our new paper on how we think the hippocampal contributes to pain (with @lizayoub.bsky.social, @mpmca.bsky.social & @sarahnelsonphd.bsky.social) published in @painthejournal.bsky.social www.ovid.com/jnls/pain/fu...

Our next #WINMemberMonday feature is Zheng Lian, a masters student in the Dept. of Neuroscience at the @schulichmeddent.bsky.social. Learn more about her work here. If you would like to be featured, please fill out this short form! uwo.eu.qualtrics.com/jfe/form/SV_...

trigeminal neuralgia is one of the targeted diseases. will be watching for the results

Psilocybin is safe and effective, right? Actually almost everything we think we know comes from carefully screened subjects in clinical trials, but does that generalize? We published a preprint of the first results from CO and OR healing centers. See it here: medrxiv.org/cgi/content/...

@mark-carney.bsky.social, you have such a good opportunity to dramatically increase scientific investments and recruit back all the early career scientists who have trained abroad after decades of funding cuts in our own country.

Chronic low back pain improves in a meaningful minority. What characterizes this fortunate subgroup, and what can we learn from it? #ChronicPain #LowBackPain www.michelecuratolomd.com/post/can-chr...

This graph took me 3 years to make. It's perhaps the largest-ever #metaanalysis of #TMS #BrainStim data. It includes my first real scientific discovery 🧵: When you stimulate the hand with a brief electric pulse, your brain and spinal cord are momentarily less excitable: muscle output decreases 1/n

Endometriosis takes nine years to diagnose. That’s about to change. NICE has approved two tests: a saliva test reading microRNA markers, and a gut-sensor test returning results in 45 minutes, sparing women the keyhole surgery currently needed. buff.ly/QX3jHk8 #ShareGoodNewsToo

here's how the claustrum might be involved in pain (short article!) www.sciencedirect.com/science/arti...

Major paper out: A heroic* demonstration that even acute stress increases drug intake in healthy people *4-session 2x2 RCT with ~4 oxycodone injections in 66 volunteers - with repeated blinded 2-panel stress/control inductions (ReSST) 1/🧵 www.nature.com/articles/s44...

Clinical 7T gradients can go fast — but peripheral nerve stimulation (PNS) stops you at high-res fMRI. ⚡ Meet POPE 🌍: we reshape EPI pulses to dodge PNS exactly when it spikes → robust 0.3mm fMRI, seeing intracortical veins. 🧠 w/ @SiemensHealth 👉 doi.org/10.64898/202...

We're hiring! Postdoc position to study the neural control of reaching using high-density multi-area electrophysiology. 5 years of funding, great collaborative environment. Please share with anyone who may be interested. For details, see: docs.google.com/document/d/1...

"Pain may be what the brain makes of a signal, but somewhere, Basbaum insists, there is a signal" a fantastic article by Stephani Southerland about the remarkable career of Allan Basbaum aeon.co/essays/a-res...

www.jneurosci.org/content/46/2...

July’s Research Roundup: Intimate partner violence is the leading cause of assault-caused brain injuries in women. #ResearchRoundup #ENDGBV #IPVBI #SupportSurvivors