Diamond Lab

Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.

Really crazy that these massive genes are 6% of the 1.5 Mbp genome in this bee gut symbiont:

#SynBYSS conference is scheduled on Jun 8-11, 2026 in Barcelona. Given the 100-year celebration of Architect Gaudi in Barcelona, we suggest early booking of hotels. Details can be found: www.jcvi.org/events/synbyss (speakers, abstract submission & registration) @jcvi.org @marcguellc.bsky.social

We are extremely excited to share our newly designed lab website with our friends and scientific community: www.diamondlab.bio Design/coding performed by @gabo-bellamy.bsky.social with help from @leymiloslavich.bsky.social for infrastructure support. Huge thanks for bringing to fruition!!!

🚨 Our Lab is HIRING! If you are interested in characterizing model microbiomes using genome-resolved methods, statistical/metabolic modeling, and/or machine learning please submit an application here: aprecruit.berkeley.edu/JPF05234 #postdoc #sciencejobs #biology #microbiome

I'm delighted our paper is out: doi.org/10.1093/isme... With new SAR11 isolate genomes and time-series metagenomes, we reveal coastal and offshore SAR11 ecotypes, identify associated metabolic traits, and pinpoint selective gene sweeps as a likely evolutionary driver to niche partitioning. 🌊🦠

Read more here: innovativegenomics.org/news/a-micro...

What if we could reprogram a cow's gut so it burps way less methane?🐮👏 @ucdavis.bsky.social & @innovativegenomics.bsky.social scientists found which microbes might help reduce methane w/o harming the cow. Boost that microbe & cows could become naturally cleaner for the climate! bit.ly/4oGv5YE 🧪

Proud to finally have this work published and freely available for everyone: microbiomejournal.biomedcentral.com/articles/10....

We are thrilled to announce our latest publication in the Microbiome journal in collaboration with @thehesslab.bsky.social Supplementation with red seaweed in cows reduces methane and induces previously uncharacterized hydrogenotropic bacteria. microbiomejournal.biomedcentral.com/articles/10....

📣🦠 New preprint: @savagecatsonly.bsky.social has got you covered with a new approach to building bacterial deletion libraries with unprecedented speed and ease: ow.ly/ltja50WSjBu

Telehealth companies increasingly are marketing “microdoses” of GLP-1 drugs — despite how there is virtually no evidence that smaller-than-standard doses are safe or effective.

Self-cloning crops could transform agriculture – thanks to research from IGI's Venkatesan Sundaresan, who was awarded the 2024 Wolf Prize for his research on apomixis. Read more in this feature from @nature.com: ow.ly/Q7v350WQyne

Our paper on model cyanobacterial communities by @andrejakust.bsky.social is finally typeset and looks beautiful, check it out: academic.oup.com/ismej/articl...

Out now – our reader-friendly 2025 overview of #CRISPR clinical trials! Learn about how CRISPR is being used to treat #HeartDisease, #cancer, #lupus, #RareDiseases, and more! Read here: ow.ly/mRPl50WneTS 🧬

Congrats to IGI's @pcronald.bsky.social on receiving the President’s Award for the Advancement of the Common Good from Stanford University! 🎉 Read more: news.stanford.edu/stories/2025...

UC Berkeley researchers tweaked a key enzyme involved in microbial methane production to understand the different environments on Earth that generate the greenhouse gas. news.berkeley.edu/2025/08/14/s...

Did you know that the illustrations in our resources like CRISPRpedia and our illustrated scientific glossary are free to use for non-commercial, educational purposes? Tag us to show us how you're using them! innovativegenomics.org/science-x-art/

‼️Diamond Lab is considering potential a new postdoctoral researcher. If you have strong interests in microbiomes, metagenomics, machine learning, or rumen biology drop us a line and shoot us a CV!

Love these!!! Now let’s see some communities in watercolor

Think about all the amazing chemotropic microbes that must support this system!!! I hope they took samples

Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our Science x Art page to see a selection of work from our designers & artists. Tag us to show us how you're using them! innovativegenomics.org/science-x-art/ 🧬🎨

Rally nice review on plasmid leading strand anti defense and establishment @bursteinlab.bsky.social www.sciencedirect.com/science/arti...

The Ronda lab's newest publication on targeted editing: www.nature.com/articles/s41...

Out now in Nature Biomedical Engineering from IGI's Carlotta Ronda @rondalab.bsky.social — a novel way to precisely edit the genomes of microbes in the microbiome to defeat harmful infections. Read more: ow.ly/efsS50WsVen

We’re thrilled to announce IGI–Bakar Labs. This new building will allow the IGI to continue expanding our impact in health and agricultural applications of #CRISPR, and will be shared with the Bakar Labs incubator for growing biotech companies. Learn more: news.berkeley.edu/2025/07/17/c...

Very excited to now share publicly that @innovativegenomics.bsky.social will be expanding to an amazing new building in the 2028 - 2029 academic year! innovativegenomics.org/news/igi-bak...

Our friends @thehesslab.bsky.social are actively looking for postdoctoral researchers interested in anerobic microbiology, and studying the rumen microbiome. #microbiologists #bioinformatics #microbiomes Check out their website: hesslab.com

Out now in TIME — @jenniferdoudna.bsky.social on IGI's new initiative, teaming up with the @chanzuckerberg.bsky.social to create a new center for pediatric #CRISPR cures! Read here: ow.ly/E5un50WnbCi

Hot off the presses: our reader-friendly 2025 overview of #CRISPR clinical trials! 🧬 Check it out here: ow.ly/mRPl50WneTS

Click on the post for more info about the paper!!!

Dive into our lab’s first peer-reviewed publication—co-led with our friends @benadler.bsky.social and Muntathar Al-Shimary from the @doudna lab! If you’ve already read the preprint, don’t miss the new updates: doi.org/10.1038/s415... @naturemicrobiol.bsky.social

🚨 Fresh from the press! We created and analyzed over 100 in vitro cyanobacterial consortia using well-characterized model cyanobacterial hosts to better understand how cyanobacteria recruit and interact with their microbiomes. Check it out: doi.org/10.1093/isme...

Out now from @diamondlab.bsky.social — stable microbiome communities using tractable cyanobacteria. An important development for folks working on cyanobacteria, microbial community formation and establishment in lab settings, and microbial community ecology! Read here: tinyurl.com/3cs2x6r7

🥳🥳 Our work exploring the core microbiomes of stable cyanobacterial communities is now out in the @isme-microbes.bsky.social Journal!!! Excellent work by @andrejakust.bsky.social and company! #microbiology #cyanobacteria #metagenomics

Globally, roughly a third more power is being generated from the sun this spring than last. If this exponential rate of growth can continue, we will soon live in a very different world, @billmckibben.bsky.social writes.

We’re happy to share our preprint where applied phages to Microbiomes to test microbial interaction hypotheses - without losing the relevance of the community. Bonus: using SNPs we studied how our targeted organism recovers from infection, and find how the community likely influences this process.

Also if you want to construct phylogenetic trees across the tree of life, also brought to you by the FoldSeek team...Unicore doi.org/10.1093/gbe/...

Some very nice multiple protein alignment software based on predicted structure brought to you by the folks behind #MMseqs and #FoldSeek ... Gotta try out FoldMason!! www.biorxiv.org/content/10.1...

Really fantastic paper on plasmid copy number control. Environmental plasmids are critical and surprisingly understudied tools for microbial community editing and manipulation www.nature.com/articles/s41...

Hello Bluesky! Our lab is very excited to be here. This is post is a little older but is a really lovely article by the @washingtonpost.com and @shannonosaka.bsky.social about some of the work we are doing on microbiomes to combat climate change! www.washingtonpost.com/climate-solu... #microbiome