Kip Ludwig

Let me ruin the suspense for you. This isn't 3-D chess. It's not even Chutes and Ladders. This is dumb monkeys flinging their own feces at those passing by because we were stupid enough to let them.

Paradromics: FDA expands Connect-One BCI study nationwide paradromics.com/news/paradro... #BCI #NeuroTech

Hyperexcitability at 25 Hz bioniclab.substack.com/p/hyperexcit... by @bioniclab.bsky.social in the "Why BCIs fail series"; "Then the seizures. Epileptiform events, the runaway activity that precedes a seizure, emerged in nearly half the mice." #BCI #neuroscience

I support replacing animal testing where we can. I also study why we can't yet. The FDA just took a step that treats the replacement as closer than it is.

This week, NIH advisors rebuked RFK for harming #NIH and US science. Sheryl Gay Stolberg reported it. Then RFK posted calling her sources anonymous or corrupt. I'll say this hoping it does good: I'm an NIH scientist, I'm not anonymous, and RFK Jr is destroying NIH. More in attachment:

One day left to comment. NIH wants to hide the peer review score, not just from applicants, but from the program officers and councils who decide what gets funded. The comment window closes tomorrow, October 13.

Little know fact. Every time you hit refresh to see if your impact score came in on era commons, it lowers your score 1 point. But if you refresh past an impact score of 10 you go back to 90.

I have not watched any of the other Packer games this season besides this game against the Bears…I will assume we are the best team in the nfl

According to sources familiar with the matter, someone made up the numbers entirely, and uhhh,,,,,,,,

Earlier this year the scientific community successfully fought back on dramatic changes in Federal funding proposed by the Trump Administration.Now another RFI is proposing substantial changes that would damage peer review. This letter from SDB President Helen McNeill lays out the issue clearly 1/n

Oh I shd add: Deisseroth’s work was (say it w me!) supported with public funding through federal science agencies incl NIH, NSF, and DARPA. And I daresay few political deciders in 2004 would have been excited to put algal proteins in HEK cells or neurons. Scientists knew, though.

Neurotech Job seekers: We relaunched neurotechjobs.io! New site, with a new newsletter coming soon. Share your perspective and please share with your colleagues looking for work in this field! forms.gle/MokuufDEKXyo...

#Neuralink on representational drift (until recently): "Users spend an average of 55 minutes per week calibrating simply to maintain control." neuralink.com/updates/pret... "Calibrating each decoder to peak performance could take the better part of their mornings." #BCI #NeuroTech

Faculty position opening in computational neuroscience at Duke University. academicjobsonline.org/ajo/jobs/32697

www.reddit.com/r/NIH/s/WdDl...

The person who thinks that he has the ability to decide which science to fund out of hundreds of subfields is exactly the person who should not make that decision. There is a reason that expert committees of scientists review and give recommendations for funding. No one person can know all of it.

Job Alert: Our department is looking to recruit an eminent scholar for a distinguished, endowed professorship (full professor, tenured) in the domain of human neuroscience with high clinical relevance. Please broadcast widely! For application information, see academicjobsonline.org/ajo/jobs/32753

(LinkedIn) Intracortical microstimulation (#ICMS) patterns affect cell-specific myelination, so myelin insulation is not a fixed given in brain stimulation www.linkedin.com/posts/tkozai... "Oligodendrocytes respond to the pattern of the pulses"; by @bioniclab.bsky.social on #BCI #neuroscience

I’ve been listening to the #Beatles albums in order to pass time during cardio workouts. I love them, but if you are killing yourself near the end of a #workout, having ”I‘m So Tired” from the #WhiteAlbum come on unexpectedly may be the worst pump up song ever.

(LinkedIn jobs) #Phosphoenix is looking for a senior medical device engineer - neurotechnology www.linkedin.com/jobs/view/44... Aiming for an #LGN brain implant; #Europe #BCI #NeuroTech #blindness

By the power vested in me by my old Blockbuster video rental card, I officially rename the #WhiteHouse La Maison De Douchebag.

Scientific peer review must remain the primary foundation of NIH funding. SfN is concerned about NIH's proposed changes to grant review and funding decisions. Read our statement: vist.ly/5fpaa

I am hereby exclusively calling #LLM based #AI word guessing programs. #dontbelievethehype

I’m one of 155 physicians & scientists who signed this open letter calling on elected officials to end the vilification & harassment of scientists like Peter Hotez & Anthony Fauci We urge them to “stop these witch-hunts” www.medpagetoday.com/washington-w...

Whew, the editors of @science.org are getting real.

I co-sign this great summary from @dereklowe.bsky.social . The goal is to destroy academic science, and these are the reasons. And all the “gold standard” and “needs reform” and “not high risk” stuff is transparent bullshit to hide the ball on what they are doing.

100% on target—this is the way to think about the Trump science plan.

Long-term safety and efficacy of intracortical microstimulation in humans www.science.org/doi/10.1126/... "electrodes maintained sufficient activity for 2 to 10 years; #ICMS #BCI #NeuroTech

“if I was trying to ruin American leadership in scientific research this is pretty much the kind of rule I would write.” Worth reading the whole thing from @dandrezner.bsky.social . I have two things to add to what he says: 1/

I’ve just come to the shocking self-realization that both my science and comedy writing are essentially the same thing. I bluntly say a bunch of blatantly obvious things that for whatever reason people have sub consciously avoided thinking about. Ironically, I never caught that before myself.

Regardless of party, can we all agree not to support very bad people? The #whataboutism has got to stop. #goodpeopleoverparty

www.nytimes.com/2026/07/06/u... an ominous trend: graduate admissions are down 15 percent from last year, on top of an 11 percent decrease from the previous year we are destroying our seed corn

“Our study reveals prevalent brittleness in the presence of simple adversarial transformations: leading systems can guess the correct answer even with key inputs removed yet may get confused by the slightest prompt alterations…” #AI www.nature.com/articles/s41...

Roughly half of intracortical microelectrodes lose recording capability within a year of implantation. The B.I.O.N.I.C. Lab at Pitt is hiring a postdoc to attack the mechanism on two parallel grant-funded threads. 🧵 (1/7)

Seen on the wall at a local bar:

A @nejm.org editorial today on the Office of White House Management and Budget (OMB) regarding their new funding proposal and politicization of science www.nejm.org/doi/full/10....

I keep seeing how #Elon #Musk will be the world's first trillionaire with the SpaceX IPO. If you take the value of all wealth and assets, the whole world is estimated at ~450 trillion dollars. There are ~8.3 billion people. For 1 person to have 1/450 of ALL OF IT is neither sustainable nor ethical.

The good news is knowing IS half the battle. The bad news is the other half usually involves killing people. #GIJoe kind of glossed over that part growing up.

They published it at 412 pages on a Friday afternoon, the slot networks call "take out the trash." OMB-2026-0034 lets political appointees override peer review, ban publication funding, and terminate grants without cause. They gave you 45 days. They're counting on you not reading it.

Neuropixels + Optogenetics = Neuropixels Opto Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors. Today in @natmethods.nature.com doi.org/10.1038/s415... Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.

OMB just published 412 pages in the Federal Register (Docket OMB-2026-0034) giving political appointees authority to terminate any NIH grant, override peer review scores, and block you from publishing with federal funds. Comment period closes ~July 13. Thread 🧵

The White House today announced it plans to make major changes in how the U.S. government manages research funding. https://scim.ag/43HgW4s

⚠️ Late Friday afternoon, May 15, while reporters were leaving for the weekend, HHS quietly cut more NIH staff and began moving senior career employees into "at-will" status under the renamed Schedule F. No press release. No published list. A "first tranche," with more to come. 🧵

This is the slow death of NIH by design. The architect is Russell Vought. He is the man who architected the RIFs & probationary terminations. He devised the multiyear funding and censorship schemes. If you don't like what you see, let's get him impeached: actionnetwork.org/forms/civil-...

🧠 Half of animals receiving the most commonly used clinical brain stimulation frequency developed seizure-like activity. But only after six weeks. Long past the point where most safety studies stop looking. New paper, final version out in Biomaterials. 🧵

🗑️ Every neuron in your brain has a waste management system. When it fails near a chronically implanted electrode, the cell does not die immediately. It accumulates damage quietly, for weeks, before it shows up in your recordings. 🧵

I would like to announce that I will also be blocking the Straight of #Hormuz in addition to the #UnitedStates and #Iran. Our dog Lily will be joining me. So now it’s like really, really quadruple blocked. Especially if you are a squirrel. 🐿️

I have a new favorite study: www.nature.com/articles/d41...

Slaughtering our golden goose: massive budget cuts for US science proposed again by Trump administration www.nature.com/articles/d41...

🚨 Congress held NIH and NSF budgets roughly flat. Scientists celebrated. Here is what actually happened. NIH awarded 4,641 fewer grants in FY2025 than the 4-year avg. New awards dropped 14%. Over $1.3B never reached investigators. NSF awards fell 22%. The money was there.