My main PhD paper is finally out! 🎉
After ~5 years, it’s published today in 𝘕𝘢𝘵𝘶𝘳𝘦 𝘐𝘮𝘮𝘶𝘯𝘰𝘭𝘰𝘨𝘺.
@natimmunol.nature.com
It all started with an unexpected observation 🔍:
👉 Mice lacking the dendritic cell receptor DNGR-1 developed tumours earlier ⏩ and more frequently 📈 than wild-type mice.
1/11 🧵
Attending #ESMO26? 📲 Have you checked out the App?
Here’s a useful guide, especially for those who have not used it before - there’s a video demo in the link below 👇
#ESMOAmbassadors
Attending #ESMO26? 📱Download the ESMO Events App to browse the programme, save your must-attend sessions and create your personalised agenda before you arrive.
A simple step to help you make the most of your congress experience from day one.
🔗 https://ow.ly/7ycy50ZZXgI
Discover “Targeted cancer #immunotherapy with PD-1 blockade” with Antoni Ribas, recipient of the 2026 ESMO Lifetime Achievement Award, at the #ESMO26 Congress Opening Session.
🔗 https://ow.ly/rQjb50ZXThn
What helps sustain motivation and meaning in oncology? The fostering #resilience under fire session at #ESMO26 explores resilience, professional identity, impostor syndrome and trainable coping skills.
🔗 https://ow.ly/mTBs50ZZK61
The countdown to #ESMO26 begins… looking forward to seeing many colleagues and friends in Madrid 🇪🇸, and the practice-changing data that will be showcased.
#ESMOAmbassadors@myesmo.bsky.social
Presidential Symposium I at #ESMO26#Melanoma, #bladder, #lung and #prostate cancers: late-breaking data that can change clinical practice across diseases.
➡️ https://ow.ly/z1el50ZYpGo@fandremd.bsky.social
🐝 Celebrating 1️⃣ year of Prof Samra Turajlić leading @cruk-mi.bsky.social, marked by our inaugural The Christie Ignite Lecture.
Bringing scientists and clinicians together to ask: “𝘞𝘩𝘢𝘵 𝘤𝘰𝘶𝘭𝘥 𝘸𝘦 𝘥𝘰 𝘵𝘰𝘨𝘦𝘵𝘩𝘦𝘳?”
Big questions. Shared ambitions. Patients at the heart.
Thank you, Samra!
#TeamScience
🧑🔬 𝗜𝗻𝘁𝗲𝗿𝗲𝘀𝘁𝗲𝗱 𝗶𝗻 𝗰𝗮𝗻𝗰𝗲𝗿 𝗶𝗺𝗺𝘂𝗻𝗼𝗹𝗼𝗴𝘆? 𝗟𝗼𝗼𝗸𝗶𝗻𝗴 𝗳𝗼𝗿 𝗮 𝗣𝗵𝗗 𝗼𝗽𝗽𝗼𝗿𝘁𝘂𝗻𝗶𝘁𝘆?
We're looking for a clinician to join us in Manchester to explore “𝗶𝗺𝗺𝘂𝗻𝗲 𝗳𝗶𝘁𝗻𝗲𝘀𝘀” - how cancer tx, ageing & comorbidities shape immunity + what this means for response, toxicity & recovery.
@mcrcnews.bsky.social
🔗 Further info:
𝗦𝘂𝗽𝗲𝗿𝘃𝗶𝘀𝗼𝗿𝘆 𝘁𝗲𝗮𝗺:
Dr Jonathan Lim, Prof Samra Turajlić, Prof Mark Travis, Prof Omer Aziz, Prof Magnus Rattray and Dr Elizabeth Appleton.
🌍 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗣𝗵𝗗 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 - 3 years; outstanding applicants from outside the UK welcome
🗳️ Apply by 23 Nov 2026
@cruk-mi.bsky.social@uom-dcs.bsky.social
The #ESMOAmbassadors represent expertise across tumour types and oncology disciplines.
Explore their profiles and discover which Ambassadors to follow during #ESMO26.
🔗 https://ow.ly/cyUC50ZOEjF
ESMO is pleased to announce the #ESMOAmbassadors for #ESMO26.
They will share scientific highlights, expert perspectives and insights on the latest research presented at #ESMO26 across tumour types and disciplines.
🔗Discover the Ambassadors: https://ow.ly/BQ3i50ZOkEv
Great to be here in Suzhou 🇨🇳 this week for #CSHAsia Cancer Immunotherapy meeting. Looking forward to learning from colleagues and discussing science 👇
#CSHAsia#CancerImmunotherapy#Immunology#CancerResearch
Join us this September for the CSHA Symposium on Cancer Immunotherapy!
👉 Submit your registration: www.csh-asia.org?content/2986
📣 #ESMO26: Join Prof. James Larkin, Scientific Committee Co-Chair, to exchange perspectives, debate emerging evidence, and discuss the future of cancer prevention, diagnosis, and treatment.
⏰ Late registration deadline: 16 September 2026
🔗 https://ow.ly/q9GM50ZJcZh#esmomeetings
Welcome, Professor Mahima Swamy! 💜
An internationally recognised researcher in intestinal immunology, Professor Swamy has joined the University of Manchester's Lydia Becker Institute as Professor of Immunology, strengthening its world-class expertise in barrier immunity.
WORLD-LEADING IMMUNOLOGIST TAKES UP TOP UOM ROLE ⬇️🦠
Leading immunologist and cytokine biologist, Prof. Sarah Gaffen has been appointed as the new director of The Lydia Becker Institute of Immunology and Inflammation.
Welcome, Sarah! 💫
@lydiabeckeriii.bsky.social
🎓 Massive congratulations to our fantastic Medical Oncology honorary consultant colleagues at The Christie NHS Foundation Trust on their promotions to 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗖𝗵𝗮𝗶𝗿𝘀 @manchester.ac.uk!
🌟Prof Sacha Howell
🌟Prof Natalie Cook
🌟Prof Colin Lindsay
@uom-dcs.bsky.social@mcrcnews.bsky.social
Hope you enjoy this short piece, which came out yesterday. Some thoughts I’ve been musing on for a while about why adaptive immunity evolved. Read it for free at rdcu.be/fAO5P
As an early-phase trialist, I never stop being amazed by the bravery & generosity of people who step forward into the unknown. Patients like Tracy don't just shape their own care; they open doors for everyone who follows.
🔬 So it means a great deal to share a 𝗴𝗹𝗼𝗯𝗮𝗹 𝗳𝗶𝗿𝘀𝘁 🌎...
@mcrcnews.bsky.social
𝗭𝗜𝗠𝗔-𝟭𝟬𝟭 is a 1st-in-human, 1st-in-class TCR-NK cell therapy trial, which is a true collaboration between our Advanced IO/Cell Therapy team at The Christie & the Zelluna team.
Those in the know understand how much happens behind the scenes. Setting up a cell therapy study is never straightforward.
We're still early in the trial, but this feels like the right moment to recognise the multidisciplinary team who made it possible 🙌.
Fiona & I couldn't be prouder of our team. Here's to creating more opportunities for patients through research. 💙
📻 𝗕𝗕𝗖 𝗥𝗮𝗱𝗶𝗼 𝟱 𝗟𝗶𝘃𝗲 [31 Jul 2026 | 1:26:37]
🚀 A major milestone for @manifest-cirrp.bsky.social.
Launching our prospective recruitment represents a significant milestone since we launched in Q4 2024. In doing so, we'll have the opportunity to learn from every patient.
@ukri.org@crick.ac.uk
📖 Read more in The Christie press release:
1/4
Many thanks to @jamestapper.bsky.social@theobserveruk.bsky.social for covering this last Sunday - featuring the story of our first participant; a powerful reminder that research is driven by patients whose generosity will benefit many others 👇
3/4
This is only possible because of an incredible collaboration 🤝 between patients, clinicians, research teams, scientists, NHS partners, industry and funders.
Thank you to everyone who has helped bring MANIFEST to this point!
4/4
🚀 A major milestone for @manifest-cirrp.bsky.social.
Launching our prospective recruitment represents a significant milestone since we launched in Q4 2024. In doing so, we'll have the opportunity to learn from every patient.
@ukri.org@crick.ac.uk
📖 Read more in The Christie press release:
1/4
𝗠𝗔𝗡𝗜𝗙𝗘𝗦𝗧 is truly a team effort.
💡 Humbled to hear our very first patient share his perspective. Experiences like his will shape how we scale up & are already helping us learn how more.
Watch this space. @manifest-cirrp.bsky.social
📰 As featured today in @theobserveruk.bsky.social 👇
🔬 Another fantastic 𝗠𝗮𝗻𝗰𝗵𝗲𝘀𝘁𝗲𝗿 𝗜𝗺𝗺𝘂𝗻𝗼-𝗢𝗻𝗰𝗼𝗹𝗼𝗴𝘆 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 (𝗠𝗜𝗢𝗡) meeting!
Great to bring together colleagues from academia, NHS & industry to showcase Manchester-led immuno-oncology research, celebrate recent presentations at major international 🌍 conferences.
@mcrcnews.bsky.social
Thank you to our speakers:
🎯 Prof Fiona Thistlethwaite
🎯 Dr Frances Turrell
🎯 Prof Claus Jørgensen
...and to everyone who joined us.
Looking forward to building even more collaborations across Manchester's IO community.
Engineer blood cancer to defeat it!👨🔬👩🔬
I'm hiring a Senior Scientific Officer at the CRUK Manchester Institute — using CRISPR to recreate the mutation combinations behind AML and MDS, and find where they're vulnerable.
Hands-on. Apply 👇
@cruk-mi.bsky.socialapps.cruk.manchester.ac.uk/recruitment/...
A great collaboration 🙌 between our Thoracic Oncology, and Advanced Immunotherapy and Cell Therapy teams at The Christie 🐝 - driven by our stellar Senior Clinical Research Fellows Federico Monaca and Rachel Woodford.
Available #OpenAccess in 𝘛𝘩𝘦𝘳 𝘈𝘥𝘷 𝘔𝘦𝘥 𝘖𝘯𝘤𝘰𝘭 👇
@christielibrary.bsky.social
Cytokine release syndrome (CRS) isn’t just a challenge in hematologic cancers -it’s increasingly relevant in solid tumours. This review dives into mechanism-driven strategies for prevention and management.
📖 buff.ly/ZDar0oT#Oncology#Immunotherapy#CancerResearch#ClinicalInsights
Great to be in Porto 🇵🇹 for ASPIC International Congress. Looking forward to 2 days of science!
Slightly shameless plug: if you’re interested in PhD, postdoc, clinician-scientist, group leader or Clinical Research Fellowship opportunities in Manchester, come say hello 👋 - I’d be happy to chat.
🧑🔬 Postdoc position available in our MRC-funded RISE team - Valletta/Lim.
The successful candidate will lead a translational project using CODEX multiplex imaging to study CRS pathogenesis in bone marrow from CAR-T patients - working with clinicians, scientists & industry.
Deadline 10 July👇
Featured on BBC News: #TeamManchester is growing. 🚀
Cancer Research UK Manchester Institute will be receiving an extra £6m a year in investment, creating 8️⃣ senior research roles: 4 group leaders, 2 senior group leaders & 2 clinician scientists.
@cruk-mi.bsky.socialwww.bbc.co.uk/news/article...
🚀 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 opportunities - come join us in Manchester!
Looking to develop your career in Oncology? Interested in building a subspecialty interest? Keen to combine clinical excellence with research?
Several exciting opportunities available at The Christie NHS Foundation Trust 👇
🚀 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 opportunities - come join us in Manchester!
Looking to develop your career in Oncology? Interested in building a subspecialty interest? Keen to combine clinical excellence with research?
Several exciting opportunities available at The Christie NHS Foundation Trust 👇
Current fellowship opportunities include:
▶️ Experimental Cancer Medicine
▶️ Uro-Oncology
▶️ Breast Oncology
▶️ Melanoma
If you're interested, or know someone who might be, please get in touch with our Fellowships team or share.
@christieinstitute.bsky.social@mcrcnews.bsky.social
How do donated tissue samples help shape future cancer treatments? Our latest blog explores the work of the MCRC Biobank, which has collected more than 230,000 samples from nearly 30,000 patients to support cutting-edge cancer research.
Read more: https://ow.ly/ozuS50Z5EsS
Almost 2️⃣ years in…
Our MANIFEST AGM convened scientists, clinicians, patient partners & industry. Keynotes from Prof Levesque & Prof Rattray + Prof Turajlić setting the course ahead.
Big thank you to all for continuing to believe in the vision; to tackle the hard questions in #CancerImmunotherapy.
💥 Really pleased to see this story finally out in @natcancer.nature.com. An elegant study built around a very cool concept. Huge congratulations to Tom Castro-Dopico, @reisesousalab.bsky.social and all colleagues involved - delighted to have played a small part in it the journey.
@crick.ac.uk
Delighted that our paper is out @natcancer.nature.com. Research led by Tom Castro-Dopico in partnership with Adendra Therapeutics reporting on a means to increase presentation of antigens from cancer cells. Read it for free at www.nature.com/articles/s43...
Nice celebration @reisesousalab.bsky.social of our recently published or in press papers. L-R: Tom Castro-Dopico, Oliver Schulz, @drjonlim.bsky.social and Mike Buck. See earlier and forthcoming posts for paper details.
🚨 We're looking for an Associate Director for Strategy & Partnerships — a pivotal leadership role that will help define how we connect, collaborate, and amplify our impact on a global stage of cancer research!
Apply below by 26.05.2026! 👇
www.cruk.manchester.ac.uk/career/mi-26...
Salary - ~£80,000
Fantastic 2 days in San Diego 🌴
for the inaugural C8 Early Career Investigators Symposium.
Happy to represent #TeamManchester + connect with an inspiring group 🌍.
A reminder that we’re not navigating academia alone - great to hear re: lessons learned & tips for future 🤝.
@mcrcnews.bsky.social
#ESMOTAT26: Drug development in oncology is increasingly moving towards integrated strategies that consider tumour cells, their microenvironment and anatomical context.
Read the Opinion by Jon Lim, FRCP PhD in the #ESMODailyReporter 📌 https://ow.ly/fFUx50YJxOP
🚨 Open for applications - Director of Scientific Core Facilities & Services!
Shape the strategic future of our core facilities and work with leading experts on cutting-edge cancer discovery and translational research 🧑🔬🔬🧪
💷 ~£100,000 ⏰ 17.5.2026
Apply 👉 www.cruk.manchester.ac.uk/career/mi-26...