Darin Takemoto

An interesting take on how AI has changed bioinformatics. It definitely makes analysis faster, but not better. It makes mistakes that are common to those new to the field, but somehow it doesn't learn. divingintogeneticsandgenomics.kit.com/posts/is-bio...

Where life is getting more expensive, even adjusting for inflation www.nytimes.com/interactive/...

We acknowledge that no one has the bandwidth for this, but if it helps: -It’s ‘sleight of hand’ -It’s ‘bated breath’ -It’s ‘lo and behold’ -It's 'buck naked' -It’s ‘brass tacks’ -It’s ‘free rein’ -It’s ‘toe the line'

Why AI may never be conscious. Right now AI is machine learning backed by a ton of compute and data that can talk to us, and nothing more. www.nature.com/articles/d41...

This is Tommy. Tommy had a question about my allegiances. Listen to the end to hear about his.

Comprehensive benchmark of somatic mutation detection in human cell lines and tissues, with recommendations for mutation calling. www.cell.com/cell/fulltex...

Planet Database xkcd.com/3311/

A classifier that can detect the use of AI in long-form writing. Unlike other classifiers, this one detects 68% of cases where the core idea was AI-generated, but was rewritten by humans, suggesting that AI-generated ideas are distinct from human-generated ideas. arxiv.org/html/2610.06...

Despite the claims of RFK Jr. there still is no autism epidemic, just improved detection. Again. medicalxpress.com/news/2026-09...

Antisense-RNA therapy results in improvements in an ALS patient caused by a rare mutation in the CHCHD10 gene. Eight other patients with mutations in the same gene have been given the therapy. www.nature.com/articles/d41...

As we should endeavor to understand the full breadth of human genomic variation and not just European variation, indigenous collaborations will become more important. doi.org/rppn

Another day, another report detailing US war crimes. www.npr.org/2026/09/17/n...

Spatial transcriptomics can be really powerful, but the data are quite noisy and it is really expensive, so only use it if you need it for the problem at hand. doi.org/rpmz

Now even Ed Sheeran is saying it was the promoter's decision www.today.com/video/ed-she...

The new Macklemore video everyone’s talking about. You might think it’s about Palestine, but it’s bigger than that. It’s about social media controlling what we see, hear, and think. It’s a call to action. Whew… “fucked up.” youtu.be/sn9EKC9nqU4?...

Macklemore is being criticized for standing up for people and against genocide and imperialism. What a world. www.aljazeera.com/video/newsfe...

A Wikipedia editor put it well: "You almost want to pat them on the head and say 'Yes, of course it will' in the same way you'd tell a small child that Santa Claus will be delivering their presents."

Every bit of this 👇

This is part of my vocabulary now 😂

Every bit of this 👇

I'm keen on AI having a transformational impact on human health. But these cure projections are wildly off-base and impossible.

Describe your musical taste in three artists, no genres: Bobbi Humphrey Cowboy Junkies La Santa Cecilia

The cyclospora outbreak has reached 13,895 cases across 47 states. The FDA has recalled 1.6 million eggs due to salmonella contamination. Screwworm cases continue to rise. And we’ve just surpassed 2,500 measles cases — breaking 2025’s record. “Make America Healthy Again.”

41 years ago, Carl Sagan gave a clear and elegant explanation of the science behind global warming.

Lake Meade is running out of water. This is outrageous. We are in deep trouble

El-Sayed: "It means holding people like RFK Jr accountable for the DOGE-ing of our public health, for which we now need to be dodging lettuce across the state of Michigan for fear of getting explosive diarrhea, which nobody ever thought you be a consequence of electing Donald Trump, but here we are"

Animaris Rex is an 18-metre-long walking 'beach animal' propelled by the wind, created by Theo Jansen as a fusion of art and engineering. Original post

16 months after a young girl died in a gene-editing trial, the study's entry in clinicaltrial. gov has finally been updated to acknowledge the death. The move comes after @science.org and @retractionwatch.com revealed the fatality 1/ science.org/content/arti...

I really recommend the 2022 documentary “It’s Quieter in the Twilight,” which profiles the scientists working in relative obscurity to keep the Voyager spacecraft operating—many of them past retirement age, but unwilling to quit until the Voyagers do. It was very sweet and thought-provoking.

The US State Department acknowledged 'an unfortunate error' after the highly inaccurate African map caused a stir.

"In an extraordinary development all 55 Uefa members resolved not to participate in future World Cups or other Fifa-run events, saying in a statement that they “unanimously and unequivocally reject” the proposals" www.theguardian.com/football/202...

Just wow. Infantino's FIFA is the most corrupt organization associated with sports, and that's saying something. www.nytimes.com/athletic/747...

A vessel-based clotting switch reduced arterial clots and vascular blockages in mice without increasing bleeding risk. In 74 patients, higher S1P levels also tracked with lower clotting activity. doi.org/hccfsr

The death of a girl in an n-of-1 Chinese base-editing trial last year is disclosed for the first time. The family paid $860,000 for the trial, and were not told of serious side effects found in primate studies with the base editor. doi.org/rgzs

Some useful tips if you want to use AI to make a graphical abstract for a journal article. Useful for those (like me) who are artistically-challenged. www.nature.com/articles/d41...

I low-key wish this was actually a thing. xkcd.com/3275/

Five authors, including Harvard geneticist George Church, pulled their names from a recent commentary paper in Nature Methods, potentially due to a “potential U.S. government restriction” on collaborations with three blacklisted BGI units. No U.S. authors are in the final author list. doi.org/rf57

This is big. The first vaccine tested to PREVENT pancreatic cancer in high-risk individuals aacrjournals.org/cancerdiscov...

User-focused tips on scientific software evaluation. The "Ten tips" series is generally useful, but this is particularly good. doi.org/rfxp

Using germline genetic data and longitudinal electronic health records to find genetic signatures that are associated with pathogenic trajectories, which can span multiple diseases. doi.org/rfxn

An encyclopedia of human enhancer-gene regulatory interactions based on a predictive model trained on QTLs from GWAS and CRISPR perturbation experiments. doi.org/rfxk

A low-cost genome sequencing method combining 1-4x genome coverage with 30x exome coverage in a single sequencing run reduces sequencing costs by 75% and allows for accurate detection of disease-causing variants and structural variations. phys.org/news/2026-07... doi.org/hb96wp

Claudia Sheinbaum is navigating a complex term marked by cartel violence, shifting relations with the U.S., and the enduring political influence of her predecessor. resist47.news keeps you informed. #resist47 #ClaudiaSheinbaum #MexicoPolitics #USMexicoRelations #CartelViolence

🚨 MANUSCRIPT ALERT 🚨 The VGP Phase I manuscript pre-print is now live on bioRxiv! 🧬 doi.org/10.64898/202... Over 8 years, the VGP generated reference genomes for more than 800 vertebrate species, spanning ~95% of vertebrate orders and delivering some of the highest-quality genomes ever produced.

Three wrongs... is an average week in FIFA-world www.espn.com/soccer/story...

A new review summarizes advances in the treatment of multiple sclerosis, with emphasis on effective disease-modifying therapies for relapsing disease and the need for better treatments to prevent progression and rebuild myelin. Read the full review: https://nej.md/3SDJGcn

The most commonly used coffee plants do not tolerate higher temperatures (arabica) or drought (robusta) induced by climate change. Scientists are looking for ways to save coffee from climate change. www.nature.com/articles/d41...