While Ed can’t make #Nido2026, the lab is well-represented by Max Erdmann, and @rebee.bsky.social ! They will be sharing some of the labs findings on coronavirus replication! Catch Max’s talk tomorrow (Wed) at 3:25, and Rebee’s poster C-0036
Emmottlab
Emmottlab
@emmottlab.bsky.social
Lab news and updates for the Emmott lab, RNA virology & proteomics at the Centre for Proteome Research, University of Liverpool, UK Lab website: emmottlab.org
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Funded PhD opportunity! (UK students only due to funder restrictions). Investigating cellular heterogeneity in tendon homeostasis and ageing using single-cell proteomics. Deadline 31st July. Project is a collaboration between the Peffers, Emmott and Thorpe labs on equine tendons. Start Oct 2026.
MSCA Postdoctoral Fellowships call opening soon. If you are a strong candidate and interested in submitting a fellowship with us, we have opportunities in several areas of virology/proteomics. See emmottlab.org Call details/eligibility: marie-sklodowska-curie-actions.ec.europa.eu/funding/msca...
New preprint! Current T7-based MNV reverse genetics can be performed by co-transfecting plasmids encoding T7 RNA polymerase and vaccinia capping enzymes. We see a further 100-1000-fold boost in titres by incorporating CD300lf-expressing BSR-T7 cells into this system. www.biorxiv.org/content/10.6...
Led by Frazer, this was a fun side project for the lab, including our three MRes project students in 2025 – @biomarkella.bsky.social, Charlotte and Shu.
Funded PhD studentship (UK students only) available on clinical proteomics, application deadline 22nd March for Oct 2026 start! This project seeks to understand treatment responses to exacerbations experienced by people with CF using proteomics. www.findaphd.com/phds/project...
Congrats to Dr @stephenholmes.bsky.social on passing his PhD viva today! Thanks to examiners Al Darby and @mtrost.bsky.social!
For those who missed the British science festival in September, the recordings and mini documentary for antiviral roller skating are now out!
🚨 Big news! We’re thrilled to announce the release of both the Behind-the-Scenes Mini-Doc and the Full Recording of Antiviral Roller Skating! 🛼✨ Now you can watch the mini-doc to see how it all came together behind the scenes: youtu.be/0nevSD1wrdg And the full performance: youtu.be/mp995EBB3Bo
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
New preprint from the lab, and joint first authors @biomarkella.bsky.social and @stephenholmes.bsky.social! Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis www.biorxiv.org/content/10.6...
Markella introduces the preprint in her thread here: bsky.app/profile/biom...
I’m excited to share our preprint introducing scpImaging, a workflow we developed to improve data quality in single-cell proteomics (SCP) by repurposing the microscopy images generated during cell isolation with the cellenONE platform www.biorxiv.org/content/10.6...
New preprint: Viral protease-mediated polyprotein processing in human astroviruses Great collaboration with Lulla lab. And the first of @leandroxneves.bsky.social proteolysis stories. More coming soon! www.biorxiv.org/content/10.1...
New preprint: IFIT3 controls IFIT1 accumulation and specificity preventing self mRNA targeting during the innate immune response. www.biorxiv.org/content/10.1... Led by Renata Fleith from the Sweeney lab.
Funded PhD opportunity through the DiMeN DTP: studying HEV proteolysis. You’ll be primarily based in the Herod lab at Leeds, and work with us on the use of MS-based proteomics to study proteolysis! www.findaphd.com/phds/project...
Emmottlab reposted
We are still buzzing from our show! Here’s some snaps of what you missed… in case you were wondering…. Huge thank you to the whole production team and the people who made this happen! @microbiologysociety.org @britsciassoc.bsky.social @emmottlab.bsky.social @livuninews.bsky.social #BSF25
The lab is being represented at the IX International Calicivirus Conference in Banff by @tartanvirus.bsky.social! Catch Frazer to talk protease substrates and proteomics.
Led by @idb-virology.bsky.social, the lab is contributing to #BSF25 with a performance of antiviral roller skating! Working with Liverpool roller birds, and supported by the BSF and @microbiologysociety.org
📣 Introducing "Antiviral Roller Skating"! ✨️🦠🛼✨️ Debuting at the British Science Festival 2025 #BSF25 in Liverpool! Exploring viruses & antivirals through movement & play! Friday 12 Sep, 18.30 @unitytheatre.bsky.social FREE tickets: britishscienceassociation-tickets.ticketsolve.com/ticketbooth/...
Emmottlab reposted
Replying to @antiviral-rskating.bsky.social
👨🔬Scientific Advisors Drs. Max Edrmann & Ed Emmott @edemmott.bsky.social 🎭 Inspiration: "Bus Regulation: The Musical" by Ellie Harrison @ellieharrison.bsky.social 💷 Funded by @microbiologysociety.org & @britishscienceassociation.bsky.social #bsf25 #scicomm #sciencecommunication #skating #sciart
Emmottlab reposted
Replying to @antiviral-rskating.bsky.social
🤝 A collaboration between @liverpooluni.bsky.social & Liverpool Roller Birds ✍️🎬 Written, Directed & Produced by Dr. I'ah Donovan-Banfield @idb-virology.bsky.social 👯♀️Choreographed by Ani Bosco 📸 Director of Photography Dr. Rebee Penrice-Randal @rebee.bsky.social 📹 Videography by Paroketh Films
New paper: collaboration with Cambridge on EMCV 2B* now published journals.asm.org/doi/10.1128/...
Emmottlab reposted
Congratulations to Markella Loi from the @emmottlab.bsky.social on winning the Early Career Award for #BSPR2025 and congratulations to @hannahmayging.bsky.social on being the runner
We have projects available on single-cell proteomics, including methods development, and applications to antiviral development and resistance. If you have a strong background in proteomics and are considering an MSCA, get in touch! marie-sklodowska-curie-actions.ec.europa.eu/news/msca-op...
Emmottlab reposted
Emmottlab reposted
As we get ready for the British Society for Proteome Research annual meeting in Liverpool (July 7-9th), we will start highlighting our amazing speakers. First is @slavov-n.bsky.social who will talk to us about Biological and technological frontiers for single-cell proteomics.
Emmottlab reposted
First 2025 paper: delighted to have contributed to this paper on the emergence of a new subgenomic mRNA in SARS-CoV-2 from the Bauer lab journals.plos.org/plosbiology/...
Another PhD studentship is available for Oct 2025 start! In a collaboration between the @pirbrightinst.bsky.social and us, you will be investigating the role of novel avian coronavirus accessory genes. See here for more details! www.findaphd.com/phds/project... Deadline 17 Feb, funded for UK only.
The deadlines for our MRC-funded studentships have now passed, but a funded studentship through the BBSRC NWD DLA is now available for Oct 2025 start in single cell mass spectrometry. See findaphd for more details or drop Ed an email. www.findaphd.com/phds/project...
Emmottlab reposted
Loading a mass spec and a nanopore in the same day! Thrilled to be learning another omics method in the @emmottlab.bsky.social 🧬
The first is based primarily in our lab and builds on our work on coronavirus and norovirus replication in collaboration with Prof Al Darby and Dr Dom Byrne. More details here: www.findaphd.com/phds/project...
The second is primarily based with Dr Helen Wright, and alongside Dr Freddy Frost to study neutrophil NETs and bronchiectasis. We provide training in proteomics and this builds on some of the clinical proteomics we have done to study CF. More details here: www.findaphd.com/phds/project...
New paper: Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1. Work led by Ileana Georgana from the Goodfellow lab www.mdpi.com/1999-4915/16...
PhD 1 (Expanding single-cell proteomics to multiomics): www.findaphd.com/phds/project... (closing date Jan 15th, open to both home and international students)
PhD 2 (Rift Valley fever virus RdRP interactome): www.lstmed.ac.uk/study/resear... (led by Alain Kohl lab, closing date Jan 21st, open to both home and international students)
PDRA 1 (Viral proteolysis of cellular substrates): Click here to apply for the role of Postdoctoral Research Associate at University Of Liverpool: my.corehr.com/pls/ulivrecr... (closing date being adjusted to Jan 22nd)
PDRA 2 (Coronavirus reverse genetics): Click here to apply for the role of Postdoctoral Research Associate at University Of Liverpool: my.corehr.com/pls/ulivrecr... (closing date being adjusted to Jan 22nd)
A second funded PhD studentship is available for Oct 2024 start! - Investigating the interactions of Rift Valley fever virus RdRP. You will be primarily based with Alain Kohl at LSTM, working with us on the LC-MS/MS portions. Deadline Jan 24. www.lstmed.ac.uk/study/resear...
News is now out officially! Hugely grateful for this award which will let us study coronavirus replication, in particular the role of polyprotein precursors over the next 8 years! Adverts for two new PDRA positions are working through HR and will be up shortly. news.liverpool.ac.uk/2023/12/01/2...
Funded PhD student ship in the lab for Oct 2024 start - expanding single-cell proteomics to single-cell multi omics. This is a CASE project in collaboration with Cellenion and SwanseaUni. Deadline Jan 15. For details see: www.findaphd.com/phds/project...
Congrats to Dr Rosie Maher whose preprint on proteomic analysis of pulmonary aspiration from her PhD studies with Rob Benton and Paul McNamara is now available on @medrxivpreprint.bsky.social : www.medrxiv.org/content/10.1...
New paper: The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity www.cell.com/iscience/ful... Delighted to have contributed to this work, led by Hazel Stewart from the Firth Lab, and Yongxu Lu!
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