The FEBS Journal

🎉 We are thrilled to share our newest collection: Biochemistry & beyond Explore our inaugural collections on: 🪴Plants & biotechnology, 🐁Organismal biology, 🫀Cardiobiology, 🔬 Developmental biology & Stem cells, 🧬RNA biology & epigenetics. Discover ➡️ buff.ly/MFwRpDl #BeyondBiochem

🔍 Featured as an Editor’s Choice article in our Issue 20, this outstanding study reveals a novel link between ER stress and AMPK signalling: Bip1 regulates AMPK signaling in response to endoplasmic reticulum stress ➡️ buff.ly/MJYtxnP Also, check out the Commentary ➡️ buff.ly/VSSJDFO #AMPK #ERstress

🎯 We invite you to read the Mini Review in Issue 20 of The FEBS Journal highlighting how targeting LRH-1's tissue-specific pathways could unlock selective, highly targeted therapies for leukemia and immunopathological diseases ➡️ buff.ly/I8gVqJV #LRH1 #leukemia #immunopathology #nuclearreceptors

🚀 Our Issue 20 is now online, packed with fascinating research from across the life sciences! From the effects of GLP-1 agonists and LRH-1 to the roles of Bip1 and Erd2 in ER stress, and new key players in the fungal bioluminescence pathway. Discover the full issue here ➡️ buff.ly/w2vS2ZJ #GLP1 #AMPK

Life relies on phosphate, but how did that dependency begin? Perhaps the answer lies deep underwater. Read more in "Hydrothermal origin of metabolic phosphorylation" @febsj.bsky.social @febspress.bsky.social #OriginOfLife #Evolution #Metabolism #MicroSky doi.org/10.1111/febs...

Delighted to share our latest publication on tumor - innate immune crosstalk in cancer cachexia out now in @febsj.bsky.social @febspress.bsky.social febs.onlinelibrary.wiley.com/doi/10.1111/... @biopatrika.bsky.social Congratulations to all the authors 🎉 #cancer #cachexia #Drosophila

🧬 We look forward to attending the EMBO-EMBL Symposium ‘The complex life of RNA’ in Heidelberg next week. 💬 Please come and meet The FEBS Journal Editor, Yeliz Yılmaz. We'd be delighted to connect and discuss great science with you! #EESRNA #FEBSPress #EMBLEvents

📣 Issue 19 is now online! 🔎 Discover our latest collection of Original Articles, Reviews, Viewpoints, and Commentaries featuring cutting-edge advances across molecular, cellular, and structural biology. ➡️ buff.ly/muOB4nI #mTOR #ALS #Rettsyndrome #PACS1syndrome #tubulin

✂️ Read this insightful Review in our Extracellular Matrix—Proteases Crosstalk Special Issue 📕 When proteases reshape barriers: Basement membrane remodelling in development, wound healing and tumour progression associated matrix instability in various pathological contexts ➡️ buff.ly/gO9XBwx #BM #ECM

📣 Call for Papers! We are excited to invite submissions for our Biochemistry & beyond collections: 🌱 Plants & Biotechnology, 🐟 Organismal Biology & Microbiology, 🫀 Cardiobiology, 🧫 Stem Cells & Development, 🧬 RNA Biology & Epigenetics. Discover more here ➡️ buff.ly/BW52kvd

🔬 Burkhard et al. discussed how pericytes contribute to the synthesis and remodelling of the ECM in different pathophysiological conditions, and shared an atlas of the pericyte matrisome: 📕 Proteolytic remodelling of the extracellular matrix by pericytes ➡️ buff.ly/NhJzFIi #pericyte #ECM #matrisome

⚠️ Final call for registration! Don't forget to register and complete your payment for The EACR Conference on 'Chromosomes in Crisis: From Chromosomal Instability to Catastrophes in Cancer Genomes' before 5 October. For further details 👉 buff.ly/KCJ2eyL #EACR #cancer #chromosomeinstability

Delighted to share our paper in @febsj.bsky.social establishing a live-cell platform for resolving autophagy dynamics in naked mole-rat cells. This work was led by our amazing MPhil student, Fangze Tong! @psalmotoxin.bsky.social @phar.cam.ac.uk doi.org/10.1111/febs...

The evolution and mechanistic versatility of the bacterial NADH dehydrogenases type II #NADH #evolution #MicroSky @febsj.bsky.social @febspress.bsky.social doi.org/10.1111/febs...

Read the review in our Extracellular Matrix—Proteases Crosstalk Special Issue, by Ricard-Blum and Fradette highlighting major bioactive collagen fragments in physiological and pathological contexts. 📕 An update on the landscape of collagen bioactive fragments ➡️ buff.ly/SUTJGV7 #ECM #collagen

✂️In an Invited Review for our Special Issue on Extracellular Matrix—Proteases Crosstalk, Solomonov and colleagues discuss the major ECM-degrading protease families: 📕 Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior➡️ buff.ly/sHKTyCY #ECM

✨ Today, we encourage you to read the State-of-the-Art Review, featured in our Special Issue on ‘Extracellular Matrix- Proteases Crosstalk’. 📕 Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease ➡️ buff.ly/rHlydpB #ECM #protease #proteolysis

✨ We’re thrilled to share ‘A Guide To…’ article, published in our latest Special Issue on ‘Extracellular Matrix- Proteases Crosstalk’. 📕 A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer ➡️ buff.ly/2OPm3sV #MMP #cancer #guide #ECM

We have been very impressed with the fast and professional handling of our manuscript by @febsj.bsky.social, with genuinely informed and insightful reviewers' comments.

✨ We invite you to explore the Editorial featured in our ‘Extracellular Matrix- Proteases Crosstalk’ Special Issue. 📕 Extracellular matrix cross-talk with proteases: A master switch for remodeling and cell regulation in health and disease ➡️ buff.ly/mAqM1kq #ECM #remodeling #proteases #ADAM #MMP

🎉 We are pleased to award The FEBS Journal Poster Prize to Daisy Bhatia for her poster presented at the FEBS Advanced Lecture Course 'MASLD: From novel liver model systems to organelle pathophysiology'. Warmest congratulations to Daisy and all of the presenters! 👏 👏"

🌟 We’re excited to share our Special Issue, ‘Extracellular Matrix—Proteases Crosstalk’, guest edited by Prof. Nikos Karamanos. ➡️ buff.ly/dtkc2Km ✂️ This issue features fifteen excellent review articles covering a broad range of topics at the intersection of proteases and extracellular matrix (ECM).

🧬 Don't miss this excellent EACR Conference on 'Chromosomes in Crisis: From Chromosomal Instability to Catastrophes in Cancer Genomes' that will take place in 3-5 November!📍Berlin 🔔Submit your abstract by 7 September! For further details 👉 buff.ly/KCJ2eyL #EACR #cancer #chromosomeinstability

🗓️Save the date! The EMBO-EMBL Symposium, ‘The complex life of RNA’, will take place this October, both virtually and in Heidelberg. ⏰ Please note that the registration deadline is 1st September (on-site) and 6th October (virtual). For details👉 buff.ly/XMYfCYA #EMBLevents #FEBSPress #EESRNA

🗓️Save the date! The EACR Conference on Cancer Metabolism will once again gather top experts in the field in Bilbao this October! Don't miss the registration and payment deadline on 7th September! For further details, please visit 👉 buff.ly/71hHRwY #EACR #cancermetabolism

⚖️ In their State-of-the-Art Review, Song and colleagues discuss how the Hippo signaling pathway has emerged as a key interorgan communication hub, translating systemic metabolic, hormonal, and microbial cues into coordinated organ responses. ➡️ buff.ly/JKe9M6X #Hippo #interorgan #YAP #TAZ #crosstalk

💉🦠Santos Dantas and colleagues recently published a review of 17 studies revealing that these medications reshape intestinal bacteria, boosting beneficial species, calming inflammation, and repairing the gut barrier to help drive better metabolic health ➡️ buff.ly/r7st54y #GLP1 #microbiota #diabetes

📢 Our Issue 16 is now live, featuring a vibrant selection of research from across the life sciences including a State-of-the-Art review, a mini review, an Editor's Choice article, Commentaries, and original research articles. Discover the full issue here ➡️ buff.ly/1N2vcFu #Hipposignaling #ADAM17

🔓 In their latest publication in the FEBS Journal, Kito et al. uncover a new player in how our bodies process Vitamin B6. A new branch of mammalian vitamin B6 metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone➡️https://buff.ly/2vT1WQe #vitaminB6 #salvage #AKR1C

🧩 In our latest issue, Veliova et al. uncover a new role for the malate–aspartate shuttle (MASh) in brown adipose tissue (BAT) energy metabolism. 📕 The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes ➡️ buff.ly/knouY86 #MASh #brownadipose #lipidmetabolism

⏰ New Issue alert! From metabolism to neurodegeneration, our latest issue is packed with cutting-edge research including review articles, an Editor's Choice, Commentaries, and a diverse collection of outstanding original research across the life sciences! Explore our Issue 15 ➡️ buff.ly/14oLm01

🧬The fourth article from our ‘RNA Biology & Epigenetics’ collection provides an extensive in vitro characterisation of the RNA binding properties of FASTK, offering valuable structural insights into the molecule. Discover the article, here ➡️ buff.ly/Gb7SrU1 #BeyondBiochem

🧬Next up in our ‘RNA Biology & Epigenetics’ collection is an intriguing study exploring how PHOX2B gene expression is regulated. Discover this outstanding article in our ‘RNA Biology & Epigenetics’ collection, here ➡️ buff.ly/qaswMen #BeyondBiochem

🧬The second article from our ‘RNA Biology & Epigenetics' collection focuses on SARS-CoV2 single-stranded RNA genome. Discover this outstanding article, here ➡️ buff.ly/fMYmfwT 🚀 At The FEBS Journal, biochemistry is the starting point – not the limit! #BeyondBiochem

🔎 Explore the outstanding research featured in our new ‘RNA Biology & Epigenetics’ collection! 🧬 This collection offers insights into the fascinating world of RNA biology and gene expression regulated by epigenetic factors. Discover our first article ➡️https://buff.ly/1KwThE3 #BeyondBiochem

🪴Delving further into our 'Plants & Biotechnology' collection, we feature another insightful study on the de novo synthesis of vitamin B6. Discover this outstanding article in our 'Plants & Biotechnology' collection, here ➡️ buff.ly/rdBodHP #BeyondBiochem

⚠️ Final call for registration! Don't miss the chance to register for the FEBS Advanced Course on ‘MASLD: From novel liver model systems to organelle pathophysiology' before 30 July. 📍Spetses, Greece 🗓️3-8 September 2026 For further details 👉 buff.ly/rOKdNPV #MASLD #liver #hepatocyte #fibrosis #HCC

🪴The second article from our 'Plants & Biotechnology' collection explores plant RNA editing and shows how S. cerevisiae serves as a valuable heterologous system for studying the intricacies of plant RNA editing. Discover it in our 'Plants & Biotechnology' collection, here ➡️ buff.ly/BFJCKzn

⏰ Our Issue 14 is online! 🧬 From targeted protein degradation to enzyme mechanisms and cancer biology, dive into our latest collection of molecular life sciences research: Discover our latest issue, here ➡️ buff.ly/DMkjMLk #E3ligase #enzyme #reversetranscriptase #tasmaniandevil #AuroraB

🔎 Explore the outstanding research featured in our new 'Plants & Biotechnology' collection! 🪴The articles in this collection cover a broad range of basic and applied studies in plant biology, genetics, ecology and biotechnology. Discover our first article in this collection, here ➡️ buff.ly/nZTiFzR

✨ Today, we invite you to read our ‘A Guide To…’ article, featured in our latest Special Issue on ‘Extracellular Matrix- Proteases Crosstalk’. 📕 A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer Read the complete guide, here ➡️ buff.ly/CAUZhe3 #MMP

Structural insights into θ‐type carbonic anhydrases 3 and 4: Tuning the directionality of CO2 hydration in a diatom febs.onlinelibrary.wiley.com/doi/10.1111/... @febsj.bsky.social

💦 Switching gears to feature this brilliant study which highlights lipid droplets as multifaceted regulators of ferroptosis in cancer. 📕 Opposing roles of DGAT-mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity ➡️ febs.onlinelibrary.wiley.com/doi/10.1111/...

🐝 Throughout the FEBS Congress, the poster sessions were buzzing with energy, our editors spent a fantastic few days discussing brilliant science. We congratulate all presenters, and extend our special congratulations to the poster prize winners Marta Kilichowska, Igor Živković and Elena Rakovoliou.

🚨 New Issue Alert!🚨 🌟 We’re excited to announce the publication of our new Special Issue, ‘Extracellular Matrix—Proteases Crosstalk’, guest edited by Prof. Nikos Karamanos (University of Patras). Explore this excellent selection of review articles here ➡️ buff.ly/L3DYFMK #ECM #protease #MMP

⌛ 48 hours and counting for the milestone 50th FEBS Congress in Maastricht! ☑️ The FEBS Journal's editors regularly attend this yearly event, and we have last-minute tips and tricks for you: '6 tips to make the 50th FEBS Congress your favourite conference' ➡️ buff.ly/G6uCRvu #FEBSCongress2026

📅 Please mark your calendars for the fourth day of the FEBS congress (July 7, 2026) for The FEBS Journal Perham Prize Lecture by Prof. Angela Gronenborn. Before the congress, get inspired by the recently published Editorial introducing Prof. Gronenborn➡️ buff.ly/fHMYdM5 #FEBSCongress #NMR

Glad to share this Viewpoint on Dual IRE1 targets, now out in @febsj.bsky.social. With @tonyavril.bsky.social, Eva Billat and Léane Legrand, from the PROSAC team @csignaling.bsky.social. febs.onlinelibrary.wiley.com/doi/10.1111/...

New publication from the PROSAC and @omics teams, on Ub and Ub-like in ER proteostasis, published @febsj.bsky.social

🧬 Street and colleagues delve into RNA-binding proteins and post-transcriptional regulatory networks in their State-of-the-Art Review published in our latest issue. 📕 Post-transcriptional regulatory networks: The dynamic interplay of RNA-binding proteins ➡️ buff.ly/xDWaTmw #RBP #RNA