Bioinformatics engineer at Seqera (seqera.io)
Genomics 🧬 | Spatial omics🔬 | technology 💻 | soccer ⚽
Working towards scalable and reproducible science with #Nextflow
Living in Montreal 🇨🇦
Christmas time is upon us 🎄🎅! What better way to count down the days till Christmas eve than with an Advent calender?
I am one day late, but here is little Nextflow advent calender I made for everyone. Check back every day at midnight EST to open a new door:
flowuenne.github.io/nextflow_adv...
🧑🏾💻 Need help with #nfcore#nextflow ( #bioinformatics ) pipelines, running or developing?
📅 We host regular helpdesks for different TZs
- 🌎 Americas: Tues. @ 14:00 ET (Today)
- 🌍 Eur/M.E./Afr: Thurs. @ 10:00-11:00 CEST
- 🌏 Asia-Pacific: Weds. @ 15:00 NZDT
Join the nf-core slack for more details!
Check out the blog post by Nextflow Ambassador Zohaib Anwar on VIRUS-MVP: a flexible and scalable workflow for genomic surveillance of priority viruses including SARS-CoV-2, Mpox, RSV, and influenza! 🦠
👉 Read now: hubs.la/Q03lM5KG0#NextflowAmbassador@nf-co.re
Check out this fantastic work on neighbourhood preference in spatial omics data from the Schapiro lab 🚀! Congratulations @chiaraschiller.bsky.social and team on a wonderful project! 👏🤩
1/
Ever wondered how to best quantify cell-cell neighbor preferences in tissues?
We compared 9+ neighbor preference (NEP) methods for analysing spatial omics data and propose a novel approach that combines the most relevant analysis features which we call COZI 🔬✨
Read more: doi.org/10.1101/2025...
You should definitely check out this amazing Nextflow podcast episode with my friend and collaborator @kbestak.bsky.social discussing microscopy and spatial omics workflows in nf-core and Nextflow! 🤩🔬🧪
🎉Episode 50 of the @nextflow.io Podcast is here!
Host @ewels.bsky.social sits down with @kbestak.bsky.social, a PhD student and active contributor to the @nf-co.re community, working at the cutting edge of #SpatialOmics and #microscopy.
🎧Catch it here: hubs.la/Q03fVPNx0
Running Nextflow pipelines on AWS ☁️? Check out the blogpost I wrote about using resource Labels with Nextflow and Seqera to get detailed pipeline run costs 💵.
Cost reporting of computational projects and workflows is critical for understanding and optimizing cloud spending
💡Our latest blog explores how resource labels can be used to tag AWS infrastructure resources for detailed cost reporting across your workflows and teams in Seqera
hubs.la/Q03bghM70
If you want to start learning #Nextflow or brush up on your basics of #Nextflow, now is the perfect time 🕑!
New training materials and support from ambassadors and experienced community members during training week help guide you through it, at your own pace!
community.seqera.io/t/nextflow-t...
The #Nextflow#Training week has begun! 🎉
New to Nextflow or need a guided intro? Watch the brand new on-demand walkthrough videos for the "Hello Nextflow" course, and learn at your own pace!
hubs.la/Q03b2-Rk0
Come and talk about your amazing projects at the #Nextflow summit in Boston 🎤!
I am very sad to miss this summit this year, but it will be a fantastic event, so make sure you to submit your abstract before the deadline 🤩!
📢 Reminder! The call for speakers at #NextflowSummit in Boston closes on Friday, Mar 14
Have groundbreaking research, novel workflows, or real-world success stories to share? This is your chance to take the stage!
⏳Submit your abstract now: hubs.la/Q039nrrG0
Great opportunity to get together with your colleagues and friends and watch the training videos to learn Nextflow together 👥.
💬 Discussing things not clear to you and sending questions to the community forum are all great ways to accelerate your learning experience and increase the fun 🚀 🤩!
🚀 Introducing #Nextflow Training Week!
A free, self-paced online training designed to help beginners get started with Nextflow.
📅 March 10-14, 2025
🎥 On-demand videos and real-time support
💬 Ask questions in our community forum
Learn more and join us: hubs.la/Q038kTQm0
Don't miss this chance to listen to my amazing colleagues Esha and Rob talk about how you can utilize Seqera Platform to help streamline your scientific data analysis! 🤩
📢 Last chance to register for our webinar happening tomorrow!
Join us to discover how Seqera is streamlining the entire data lifecycle, from pipeline runs through to downstream analysis and scientific insights.
Register now: hubs.la/Q034273k0
📣 We are hiring!
Join Yoshiji Lab at McGill University Dept of Human Genetics in Montreal, Canada!
yoshiji-lab.org/joinus
✅Fully Funded Positions
• 2 MSc Students
• 1 PhD Student
• 1 Postdoc
✅Goal: Using human genetics and multi-omics for drug target discovery and precision medicine
📣Excited to share our paper in Nature Genetics!
rdcu.be/d7mo0
Do plasma proteins mediate obesity’s effect on CAD risk?
→Using two-step proteome-wide MR, domain-aware MR, epigenomics & scRNA-seq, we prioritized endotrophin, cleaved from COL6A3, as a mediator & potential therapeutic target.
A 🧵↓
You can now use Seqera AI with MultiQC! 🤖
Get insights from your reports and chat about potential QC issues with Seqera AI, directly from inside your MultiQC reports! Fantastic new update by everyone involved at @seqera.io !
The gold standard in #bioinformatics reporting just got even better! #AI Summaries are now available in @multiqc.info🎉
Find out more: hubs.la/Q033Kjp30
Protein backbone diffusion models consistently undersample catalytically important motifs, and oversample idealized helices, raising questions about the appropriateness of these methods in designing starting points for enzyme design & evolution. From www.biorxiv.org/content/10.1...
I am organizing a local site in Montreal for this @nf-co.re hackathon 🇨🇦. Anyone in the area who is interested to help organize or join this hackathon and a potential #Nextflow training before, please DM me 😊!
Our next hackathon is rapidly approaching! 🚀
- March 24-26, 2025
- Online / local distributed sites
For the distributed sites, WE NEED YOU! 🎯
If you're able to book a meeting room and host a local site, fill in the local site registration form:
nf-co.re/events/2025/...
Do you want some AI guided help to write #Nextflow pipelines or convert your old legacy pipelines to #Nextflow? Go to seqera.io and try out Seqera AI now 🤩!
Write once, run anywhere: By wrapping your scripts to @nextflow.io, you can fully describe a computational pipeline with all of its dependencies and run it anywhere! 🧵
Nextflow4MS-DIAL: A Reproducible Nextflow-Based Workflow for Liquid Chromatography–Mass Spectrometry Metabolomics Data Processing #JASMSpubs.acs.org/doi/10.1021/...
For anyone that loves poker and card games, Balatro is such a great game! Just started playing it again on my tablet via Apple Arcade and having a blast 🎮🃏!
apps.apple.com/ca/app/balat...
Now that advent time and Christmas is over, I wanted to share the hidden easter eggs 🥚 in my #Nextflow advent calendar, for everyone that missed them. Head to flowuenne.github.io/nextflow_adv... to discover them yourself or find all cheat codes in this 🧵...
The entire Calender was developed with cursor.com using the Claude-3.5-sonnet model 🧑💻. The music 🎵 was also generated using AI with suno.com.
I didn't put a lot of emphasis on protecting the different secrets in the source code, mainly as a backup for people to proceed if getting stuck.
I hope you enjoyed this Advent calender experience and discovered some new aspects around Nextflow you might have not been aware of.
If you made it to the end of this thread and simply wanna play Nextflow snake 🐍, this is for you 🎁:
flowuenne.github.io/nextflow_adv...
Now that advent time and Christmas is over, I wanted to share the hidden easter eggs 🥚 in my #Nextflow advent calendar, for everyone that missed them. Head to flowuenne.github.io/nextflow_adv... to discover them yourself or find all cheat codes in this 🧵...
Santa's pipeline requires a specific parameter to be run, which you can reverse engineer or guess from the tip. It's of course: Rudolph.
Once you run the pipeline with:
nextflow run SantaFlowHoHoho.nf --reindeer Rudolph
You will get the next secret key: MerryNextChristmas
To use the final password, click on the reindeer and Santa emojis flying past on the final page for Day 24. This will reveal the final surprise, which I won't spoil for you here 😉
Now that advent time and Christmas is over, I wanted to share the hidden easter eggs 🥚 in my #Nextflow advent calendar, for everyone that missed them. Head to flowuenne.github.io/nextflow_adv... to discover them yourself or find all cheat codes in this 🧵...
After clicking the emojis in the correct order, you will see a success screen that will lead you to a new page, where you will be able to play Nextflow Snake. If you get a high score of at least 300 points, you will discover the next password "SantaFlowHoHoHo"...
Now that advent time and Christmas is over, I wanted to share the hidden easter eggs 🥚 in my #Nextflow advent calendar, for everyone that missed them. Head to flowuenne.github.io/nextflow_adv... to discover them yourself or find all cheat codes in this 🧵...
The first easter egg is a hidden Nextflow Snake game. To discover it, you need to click the emojis at the top in a specific order. Open the developer console of your browser and you will see a Nextflow pipeline run. The task hashes contain the code tree,tree,santa,tree,santa.
Today is the last day of my #Nextflow advent calender. It was fun doing this during December and I hope people discovered things they didn't know yet about the NF ecosystem ☺️!
flowuenne.github.io/nextflow_adv...
Merry Christmas and a Happy New Year to everyone 🎄❄️☃️🎁🎆
I hope we get many people together across Quebec (Canada) for a local site for this hackathon. If you are interested to join our local site in person, please contact me so we can plan ahead ☺️!
Excited to hack some Nextflow with many of you 👍💻
Our next hackathon is rapidly approaching! 🚀
- March 24-26, 2025
- Online / local distributed sites
For the distributed sites, WE NEED YOU! 🎯
If you're able to book a meeting room and host a local site, fill in the local site registration form:
nf-co.re/events/2025/...
An opportunity to work at an amazing place with amazing people! 🦠
“GeneLab is seeking a #Bioinformatics#ProgramDeveloper to drive research with #omics data from space biology experiments. Develop workflows and analyze data critical to human space exploration.
🔗 Apply now: tinyurl.com/8psb8uwn “
This map of Github is really cool:
anvaka.github.io/map-of-githu...
I feel right at home in Genomic Haven next to RWorld. Hope to visit some of these lands next year. Vuetopia and Vuestian look like cool places 😎.
Today is a special Nextflow advent calender entry, as you will need to have discovered the first hidden secret to solve this one.
🎅Santa needs help with his gift delivery Nextflow pipeline? Can you help him ☺️🦌🎁?!
Open door 15 on:
flowuenne.github.io/nextflow_adv...
It's exciting to see so much activity and enthusiasm in the protein folding and design space.
So many new tools available (Chai-1, Boltz-1, Protenix), can't wait to see many of them used in Nextflow pipelines like nf-core/proteinfold soon (github.com/nf-core/prot...) 🤩!
Over the weekend some busy elves have hidden a secret in my personal #Nextflow Advent calender 📆.
Would love to hear from people whether they can find it (but don't spoil the discovery for everyone else 😉).
flowuenne.github.io/nextflow_adv...
Tip: Best to discover and enjoy on 💻 versus 📱
Today's advent calender door has something for all of you that love open source software, that was recently announced at Nextflow Summit Barcelona 👀
Open the door here 🚪:
flowuenne.github.io/nextflow_adv...
We are looking for a Postdoc with a strong computational background to join our team. Want to work on the development and application of computational methods in the field of translational spatial biology? Apply now!
karriere.klinikum.uni-heidelberg.de/index.php?ac...
Anyone that tried to open door 4 of the Nextflow advent calender today but found it closed, just pushed a fix to reset cache so it should not happen again 😅☺️
flowuenne.github.io/nextflow_adv...
Today's door has something for you, if you want to learn #Nextflow!
If you are interested in spatial omics, bioinformatics, want to live in a beautiful city in Germany and work with an awesome team, you should absolutely apply for this opportunity! ☺️🚀🤩
We are looking for a Postdoc with a strong computational background to join our team. Want to work on the development and application of computational methods in the field of translational spatial biology? Apply now!
karriere.klinikum.uni-heidelberg.de/index.php?ac...