Flora Paldi

Flora Paldi

@fpaldi.bsky.social

Postdoc with @charleneboumendil.bsky.social and formerly with @Giacomo_Cavalli, former PhD student in the @marstonlab.bsky.social. HFSP Fellow, EMBO Fellow. 3D genome enthusiast!

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Flora Paldi
@fpaldi.bsky.social

Beyond honoured to receive the L'Oréal-UNESCO For Women in Science prize for my research on 3D genome organisation and cellular memory. Huge thanks to all my mentors, past and present @charleneboumendil.bsky.social, for helping me get here! #FWIS2026 #ForWomenInScience #FemmesEnScience

Flora Paldi
@fpaldi.bsky.social

Still spots available for this exciting workshop on Transcriptional Memory! 🧬 A unique meeting bridging chromatin epigenetics and gene regulatory networks, with an amazing lineup of speakers and great opportunities for discussions and networking. Oct 20-22 | Baeza, Spain 🇪🇸

Pablo Navarro@pablonavarrolab.bsky.social

Epigenetics means different things for different people. In this workshop we will discuss two major views anchored on transcriptional memory: chromatin vs networks. Come and share with us our excitement for the topic and the magnificent place, the Andalusian Baeza. urldefense.com/v3/__https:/...

urldefense.comWorkshop Transcriptional memory in health and diseaseThe idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...

Flora Paldi reposted

Pablo Navarro
@pablonavarrolab.bsky.social

The list of speakers is very nice, mixing the two fields in synergy. Many abstracts will be selected for oral presentation.

Pablo Navarro@pablonavarrolab.bsky.social

Epigenetics means different things for different people. In this workshop we will discuss two major views anchored on transcriptional memory: chromatin vs networks. Come and share with us our excitement for the topic and the magnificent place, the Andalusian Baeza. urldefense.com/v3/__https:/...

urldefense.comWorkshop Transcriptional memory in health and diseaseThe idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
Flora Paldi
@fpaldi.bsky.social

Our new review in @cp-trendscellbio.bsky.social is now online! We discuss the connection between the epigenome, 3D genome folding, gene expression and cellular memory, specifically in loop extrusion-independent contexts.

Trends in Cell Biology@cp-trendscellbio.bsky.social

3D genome folding in epigenetic regulation and cellular memory

dlvr.it3D genome folding in epigenetic regulation and cellular memoryThe 3D folding of the genome is tightly linked to its epigenetic state which maintains gene expression programmes. Although the relationship between gene expression and genome organisation is highly context dependent, 3D genome organisation is emerging as a novel epigenetic layer to reinforce and stabilise transcriptional states. Whether regulatory information carried in genome folding could be transmitted through mitosis is an area of active investigation. In this review, we discuss the relationship between epigenetic state and nuclear organisation, as well as the interplay between transcriptional regulation and epigenetic genome folding. We also consider the architectural remodelling of nuclei as cells enter and exit mitosis, and evaluate the potential of the 3D genome to contribute to cellular memory.

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